ID   GLND_HAEI8              Reviewed;         863 AA.
AC   Q4QJM6;
DT   08-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   16-JUN-2009, entry version 26.
DE   RecName: Full=[Protein-PII] uridylyltransferase;
DE            Short=PII uridylyl-transferase;
DE            EC=2.7.7.59;
DE   AltName: Full=Uridylyl-removing enzyme;
DE   AltName: Full=UTase;
GN   Name=glnD; OrderedLocusNames=NTHI2026;
OS   Haemophilus influenzae (strain 86-028NP).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=281310;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15968074; DOI=10.1128/JB.187.13.4627-4636.2005;
RA   Harrison A., Dyer D.W., Gillaspy A., Ray W.C., Mungur R., Carson M.B.,
RA   Zhong H., Gipson J., Gipson M., Johnson L.S., Lewis L., Bakaletz L.O.,
RA   Munson R.S. Jr.;
RT   "Genomic sequence of an otitis media isolate of nontypeable
RT   Haemophilus influenzae: comparative study with H. influenzae serotype
RT   d, strain KW20.";
RL   J. Bacteriol. 187:4627-4636(2005).
CC   -!- FUNCTION: Modifies, by uridylylation or deuridylylation the PII
CC       (glnB) regulatory protein (By similarity).
CC   -!- CATALYTIC ACTIVITY: UTP + [protein-PII] = diphosphate + uridylyl-
CC       [protein-PII].
CC   -!- SIMILARITY: Belongs to the glnD family.
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DR   EMBL; CP000057; AAX88771.1; -; Genomic_DNA.
DR   RefSeq; YP_249431.1; -.
DR   GeneID; 3431275; -.
DR   GenomeReviews; CP000057_GR; NTHI2026.
DR   KEGG; hit:NTHI2026; -.
DR   HOGENOM; Q4QJM6; -.
DR   OMA; Q4QJM6; MQHDLFH.
DR   BioCyc; HINF281310:NTHI2026-MON; -.
DR   GO; GO:0008773; F:[protein-PII] uridylyltransferase activity; IEA:HAMAP.
DR   GO; GO:0016597; F:amino acid binding; IEA:InterPro.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_00277; -; 1.
DR   InterPro; IPR002912; ACT_bd.
DR   InterPro; IPR005105; DUF294_Ntrans.
DR   InterPro; IPR010043; GlnD_Uridyltrans.
DR   InterPro; IPR003607; Met-dep_phosphohydro_HD.
DR   InterPro; IPR006674; Met-dep_phosphohydro_HD_sub.
DR   InterPro; IPR013546; PII_UdlTrfase/GS_AdlTrfase.
DR   PANTHER; PTHR13734:SF1; GlnD_Uridyltrans; 1.
DR   Pfam; PF01842; ACT; 2.
DR   Pfam; PF03445; DUF294; 1.
DR   Pfam; PF08335; GlnD_UR_UTase; 1.
DR   Pfam; PF01966; HD; 1.
DR   PIRSF; PIRSF006288; PII_uridyltransf; 1.
DR   SMART; SM00471; HDc; 1.
DR   TIGRFAMs; TIGR01693; UTase_glnD; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Nucleotidyltransferase; Transferase.
FT   CHAIN         1    863       [Protein-PII] uridylyltransferase.
FT                                /FTId=PRO_0000192737.
SQ   SEQUENCE   863 AA;  100122 MW;  A3281DCB51B17273 CRC64;
     MLFSPTLSSP LTPSAVKIER ENLKQFELEN FSRYSIFELI ENRCDFYDAL LIQLWQEIEL
     SEQLGIALIA VGGYGRREMF PLSDLDFLIL VEQTPSPEIE EKITQFIQFL WDCGFEVGNS
     VRTLEQCESE GKQDITIATN LLEARFLAGN RPHFDALNEL VKRADFWSKE DFFNAKVQEQ
     IERYQRYHNT AYNLEPDIKY SPGGLRDLHL LYWVALRHSG ALTLEAILQS GFIYPQEYQQ
     LQESRAFLFK VRFALHLILK RYDNRLLFDR QIKVSELLGF RGEGNPAVEK MMKCFFQALH
     RISLISNLLI QHYRENVLPS NQDTVIDQLD DDFQLINQCL CLRNSFVFQE KPARILDLFF
     YLTQYEHANI HSDTLRQLQI SLDQLSQKLC EIPAAREKFL RLFNQPNAIK RAFMPMHQYG
     VLTAYLPQWQ AIEGLMQFDL FHIYTVDEHT LRVMLKLESF LSQESAQEHP IAHRIFSQLS
     DRTLLYIAAL FHDIAKGRGG DHAELGAVDI ADFAQLHGLD RREIDTLAWL VKSHLLMSIT
     AQRRDIHDPE VVMNFAEAVQ NQVRLDYLTC LTVADICATN GNLWNSWKRS LFASLYEFTG
     RQFSQGMKEL LDYSEKSAEN RKLAQQILMR DYSDITPISI EQLWARCPED YFVRNTPKQI
     AWHTSLLVDF VEALLVKISN RFSLGGTEVF IYCQDQPHLF NKVVSTIGAK KFSIHDAQII
     TTQDGYVFDS FIITELNGEL VEFDRRRELE QALTLALQSE KLPALSIVPN RQLQHFTVQT
     DVRFLQENKK EHTQMELVAL DKAGLLAQVS QIFTELNLNL LNAKITTVGE KAEDFFILTN
     QFGQALDSQQ REILRNVLYR NIG
//