Q4QJK7 (MURI_HAEI8) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glutamate racemase
EC=5.1.1.3

Gene names

Name:	murI
Ordered Locus Names:	NTHI2050

Organism

Haemophilus influenzae (strain 86-028NP) [Complete proteome] [HAMAP]

Taxonomic identifier

281310 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus

Protein attributes

Sequence length	269 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Provides the (R)-glutamate required for cell wall biosynthesis By similarity. HAMAP MF_00258
Catalytic activity	L-glutamate = D-glutamate. HAMAP MF_00258
Pathway	Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00258
Sequence similarities	Belongs to the aspartate/glutamate racemases family.

Ontologies

Keywords
Biological process	Cell shape Cell wall biogenesis/degradation Peptidoglycan synthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cellular cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	glutamate racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 269	269	Glutamate racemase HAMAP MF_00258		PRO_1000047568

Sequences

	Sequence		Length	Mass (Da)
	Q4QJK7 [UniParc]. Last modified July 19, 2005. Version 1. Checksum: C136B54C694540E1	FASTA	269	30,545
	10 20 30 40 50 60 MDKKEKRPTV LFFDSGVGGF SVYREAKKLL PNWHYLYCFD NAGFPYSERE EESIIHRTLA 70 80 90 100 110 120 ACQLINQRYP LDAIVIACNT ASTVVLPPLR AAFEIPIIGT VPAIKPASEI TKTKHIGLLA 130 140 150 160 170 180 TKGTVKRHYI DELIDKFAQD CIVERLGTTK LVEIAEQKIR GHSVDLISLK DELSSWAGMA 190 200 210 220 230 240 DLDTLVLGCT HFPLIKDEIQ LCLPQVKYFM DPSAAIAKRI KYLLDDKNLQ VQNEKYNQMF 250 260 CTAHFPEESQ FKKALHLWGF ESLEVIKID

References

[1]

"Genomic sequence of an otitis media isolate of nontypeable Haemophilus influenzae: comparative study with H. influenzae serotype d, strain KW20." Harrison A., Dyer D.W., Gillaspy A., Ray W.C., Mungur R., Carson M.B., Zhong H., Gipson J., Gipson M., Johnson L.S., Lewis L., Bakaletz L.O., Munson R.S. Jr. J. Bacteriol. 187:4627-4636(2005) [PubMed: 15968074] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 86-028NP.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000057 Genomic DNA. Translation: AAX88790.1.
RefSeq	YP_249450.1. NC_007146.2.
3D structure databases
ProteinModelPortal	Q4QJK7.
ModBase	Search...
Protein-protein interaction databases
STRING	Q4QJK7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3431299.
GenomeReviews	Gene locus NTHI2050 in contig CP000057_GR.
KEGG	hit:NTHI2050.
PATRIC	20184124. VBIHaeInf100748_1890.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0796.
HOGENOM	HBG645102.
OMA	PQEDTIY.
PhylomeDB	Q4QJK7.
ProtClustDB	PRK00865.
Enzyme and pathway databases
BioCyc	HINF281310:NTHI2050-MONOMER.
Family and domain databases
HAMAP	MF_00258. Glu_racemase. [Tree]
InterPro	IPR015942. Asp/Glu/hydantoin_racemase. IPR001920. Asp/Glu_race. IPR018187. Asp/Glu_racemase_AS. IPR004391. Glu_race. [Graphical view]
Gene3D	G3DSA:3.40.50.1860. Asp/Glu_race. 1 hit.
KO	K01776.
PANTHER	PTHR21198. PTHR21198. 1 hit.
Pfam	PF01177. Asp_Glu_race. 1 hit. [Graphical view]
SUPFAM	SSF53681. Asp/Glu_race. 2 hits.
TIGRFAMs	TIGR00067. Glut_race. 1 hit.
PROSITE	PS00923. ASP_GLU_RACEMASE_1. 1 hit. PS00924. ASP_GLU_RACEMASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MURI_HAEI8

Accession

Primary (citable) accession number: Q4QJK7

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	July 19, 2005
Last modified:	January 25, 2012
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program