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Protein

Guanylate kinase

Gene

gmk

Organism
Haemophilus influenzae (strain 86-028NP)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.UniRule annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi11 – 18ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseUniRule annotation (EC:2.7.4.8UniRule annotation)
Alternative name(s):
GMP kinaseUniRule annotation
Gene namesi
Name:gmkUniRule annotation
Ordered Locus Names:NTHI2054
OrganismiHaemophilus influenzae (strain 86-028NP)
Taxonomic identifieri281310 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
Proteomesi
  • UP000002525 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002663321 – 208Guanylate kinaseAdd BLAST208

Structurei

3D structure databases

ProteinModelPortaliQ4QJK3.
SMRiQ4QJK3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 185Guanylate kinase-likeUniRule annotationAdd BLAST182

Sequence similaritiesi

Belongs to the guanylate kinase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000037638.
KOiK00942.
OMAiAGNYYGT.
OrthoDBiPOG091H01Q4.

Family and domain databases

HAMAPiMF_00328. Guanylate_kinase. 1 hit.
InterProiView protein in InterPro
IPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like_dom.
IPR017665. Guanylate_kinase.
IPR020590. Guanylate_kinase_CS.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00625. Guanylate_kin. 1 hit.
SMARTiView protein in SMART
SM00072. GuKc. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR03263. guanyl_kin. 1 hit.
PROSITEiView protein in PROSITE
PS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q4QJK3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQGNLYILS APSGAGKSSL ISALLASDSS TQKMVSVSHT TRAPRPGEVE
60 70 80 90 100
GVHYYFVSKE EFESLIEQDL FLEYAKVFGG NYYGTSLPAI EENLAKGIDV
110 120 130 140 150
FLDIDWQGAQ QIRKKVPSVK SIFILPPSLP ELERRLIGRG QDSEEVIAER
160 170 180 190 200
MSKAISEISH YDEYDYVIVN DDFEKTLKDL QSILQSERLT KDYQQKQNAM

LIQQLLAK
Length:208
Mass (Da):23,401
Last modified:July 19, 2005 - v1
Checksum:i76E7F92253BE757B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000057 Genomic DNA. Translation: AAX88794.1.
RefSeqiWP_005649899.1. NC_007146.2.

Genome annotation databases

EnsemblBacteriaiAAX88794; AAX88794; NTHI2054.
KEGGihit:NTHI2054.

Similar proteinsi

Entry informationi

Entry nameiKGUA_HAEI8
AccessioniPrimary (citable) accession number: Q4QJK3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: July 19, 2005
Last modified: March 28, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome