Q4QJI5 (Q4QJI5_LEIMA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative dihydrolipoamide branched chain transacylase EMBL CAJ01934.1
EC=2.3.1.- EMBL CAJ01934.1

Gene names

ORF Names:

LMJF_05_0180 EMBL CAJ01934.1

Organism

Leishmania major

Taxonomic identifier

5664 [NCBI]

Taxonomic lineage

Eukaryota › Euglenozoa › Kinetoplastida › Trypanosomatidae › Leishmania

Protein attributes

Sequence length	477 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the 2-oxoacid dehydrogenase family. RuleBase RU003423 Contains 1 lipoyl-binding domain. RuleBase RU000447

Ontologies

Keywords
Domain	Lipoyl RuleBase RU000447
Molecular function	Acyltransferase RuleBase RU003765 EMBL CAJ01934.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	fatty-acyl-CoA biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	cofactor binding Inferred from electronic annotation. Source: InterPro dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q4QJI5 [UniParc]. Last modified July 19, 2005. Version 1. Checksum: 6BDA43D1D3D257D4	FASTA	477	50,189
	10 20 30 40 50 60 MRSARCMVRR CIGAAAGAAT VAHASGWPYT ASRRHLFATT CAPLGRCIPY RLADIGEGIT 70 80 90 100 110 120 EVQVLGVCVK AGDTINEFDP ICEVQSDKAT VDITSRYTGV VKAVYLQPGA TAKVGSVMLD 130 140 150 160 170 180 IVPEGADDAP EAASPSRSAP PPSSAPDSAP QATYSASKPS SDASAGKVLA TPATRYLARE 190 200 210 220 230 240 HKLDLAHVPA TGKGGRVTKE DVLQFMDAGM SAAAAPSPPS TASSAATAPP GTVVSGLQTE 250 260 270 280 290 300 AGDTVMPITG VRRGMVKTMS QAASIPTFTF SEECELTRLM EVRGSLKDVV KERSKGKAKL 310 320 330 340 350 360 SFMPFFLKAA SIALQHHPDI NAHCPVDCSA LVRKAAHNIG FAMDTPNGLI VPVVKHVERK 370 380 390 400 410 420 SILDIANDMQ VLIERGKSNK LTTQDMTGGT FTLSNIGVIG ATVTTPVLLP PQVAIGAIGR 430 440 450 460 470 LQKLPRFDAN GSLYAANLIC VSFTADHRVI DGASMVRFAN TYKQLLEHPE NMLVDLR

References

[1]

"The genome of the kinetoplastid parasite, Leishmania major." Ivens A.C., Peacock C.S., Worthey E.A., Murphy L., Aggarwal G., Berriman M., Sisk E., Rajandream M.A., Adlem E., Aert R., Anupama A., Apostolou Z., Attipoe P., Bason N., Bauser C., Beck A., Beverley S.M., Bianchettin G. , Borzym K., Bothe G., Bruschi C.V., Collins M., Cadag E., Ciarloni L., Clayton C., Coulson R.M.R., Cronin A., Cruz A.K., Davies R.M., De Gaudenzi J., Dobson D.E., Duesterhoeft A., Fazelina G., Fosker N., Frasch A.C., Fraser A., Fuchs M., Gabel C., Goble A., Goffeau A., Harris D., Hertz-Fowler C., Hilbert H., Horn D., Huang Y., Klages S., Knights A., Kube M., Larke N., Litvin L., Lord A., Louie T., Marra M., Masuy D., Matthews K., Michaeli S., Mottram J.C., Mueller-Auer S., Munden H., Nelson S., Norbertczak H., Oliver K., O'neil S., Pentony M., Pohl T.M., Price C., Purnelle B., Quail M.A., Rabbinowitsch E., Reinhardt R., Rieger M., Rinta J., Robben J., Robertson L., Ruiz J.C., Rutter S., Saunders D., Schaefer M., Schein J., Schwartz D.C., Seeger K., Seyler A., Sharp S., Shin H., Sivam D., Squares R., Squares S., Tosato V., Vogt C., Volckaert G., Wambutt R., Warren T., Wedler H., Woodward J., Zhou S., Zimmermann W., Smith D.F., Blackwell J.M., Stuart K.D., Barrell B.G., Myler P.J. Science 309:436-442(2005) [PubMed: 16020728] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MHOM/IL/81/Friedlin.

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Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FR796401 Genomic DNA. Translation: CAJ01934.1.
RefSeq	XP_001687494.1. XM_001687442.1.
3D structure databases
ProteinModelPortal	Q4QJI5.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblProtists	LmjF.05.0180:mRNA; LmjF.05.0180:pep; LmjF.05.0180.
GeneID	5648879.
KEGG	lma:LmjF05.0180.
Organism-specific databases
EuPathDB	EupathDB:LmjF.05.0180.
Phylogenomic databases
HOGENOM	HBG630916.
OMA	SNIGPIG.
PhylomeDB	Q4QJI5.
ProtClustDB	CLSZ2457496.
Family and domain databases
InterPro	IPR003016. 2-oxoA_DH_lipoyl-BS. IPR001078. 2-oxoacid_DH_actylTfrase. IPR000089. Biotin_lipoyl. IPR023213. CAT-like_dom. IPR004167. E3-bd. IPR015761. Lip_Acyl_TA. IPR011053. Single_hybrid_motif. [Graphical view]
Gene3D	G3DSA:3.30.559.10. CAT-like_dom. 1 hit. G3DSA:4.10.320.10. E3_bd. 1 hit.
KO	K09699.
PANTHER	PTHR23151:SF11. Lip_Acyl_TA. 1 hit.
Pfam	PF00198. 2-oxoacid_dh. 1 hit. PF00364. Biotin_lipoyl. 1 hit. PF02817. E3_binding. 1 hit. [Graphical view]
SUPFAM	SSF47005. E3_bd. 1 hit. SSF51230. Hybrid_motif. 1 hit.
PROSITE	PS50968. BIOTINYL_LIPOYL. 1 hit. PS00189. LIPOYL. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q4QJI5_LEIMA

Accession

Primary (citable) accession number: Q4QJI5

Entry history

Integrated into UniProtKB/TrEMBL:	July 19, 2005
Last sequence update:	July 19, 2005
Last modified:	November 16, 2011
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)