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Protein
Submitted name:

Programmed cell death 6 protein-like protein

Gene

LMJF_13_1460

Organism
Leishmania major
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi80 – 801Calcium 1Combined sources
Metal bindingi82 – 821Calcium 1Combined sources
Metal bindingi84 – 841Calcium 1Combined sources
Metal bindingi86 – 861Calcium 1; via carbonyl oxygenCombined sources
Metal bindingi91 – 911Calcium 1Combined sources
Metal bindingi116 – 1161Calcium 2Combined sources
Metal bindingi118 – 1181Calcium 2Combined sources
Metal bindingi120 – 1201Calcium 2Combined sources
Metal bindingi122 – 1221Calcium 2; via carbonyl oxygenCombined sources
Metal bindingi127 – 1271Calcium 2Combined sources

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

CalciumCombined sources, Metal-bindingCombined sources

Names & Taxonomyi

Protein namesi
Submitted name:
Programmed cell death 6 protein-like proteinImported
Gene namesi
ORF Names:LMJF_13_1460Imported
OrganismiLeishmania majorImported
Taxonomic identifieri5664 [NCBI]
Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeLeishmaniinaeLeishmania
Proteomesi
  • UP000000542 Componenti: Chromosome 13

Interactioni

Protein-protein interaction databases

STRINGi5664.LmjF.13.1460.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1Y1XX-ray1.95A/B53-234[»]
ProteinModelPortaliQ4QG08.
SMRiQ4QG08. Positions 53-234.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ4QG08.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini67 – 10236EF-handInterPro annotationAdd
BLAST
Domaini103 – 13836EF-handInterPro annotationAdd
BLAST
Domaini139 – 16830EF-handInterPro annotationAdd
BLAST
Domaini169 – 20436EF-handInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG0037. Eukaryota.
ENOG410YKQK. LUCA.
HOGENOMiHOG000256123.
InParanoidiQ4QG08.
OMAiIHHPGAY.

Family and domain databases

Gene3Di1.10.238.10. 1 hit.
InterProiIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
[Graphical view]
PfamiPF13499. EF-hand_7. 2 hits.
[Graphical view]
SMARTiSM00054. EFh. 3 hits.
[Graphical view]
SUPFAMiSSF47473. SSF47473. 1 hit.
PROSITEiPS00018. EF_HAND_1. 3 hits.
PS50222. EF_HAND_2. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4QG08-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAYPYNAYLG YTQPPTQYGQ PPVVAGAHGH LPVTTPLPYN AQSAYGGAQP
60 70 80 90 100
PMPTSTGVYA PSARHMNDNQ ELMEWFRAVD TDGSGAISVP ELNAALSSAG
110 120 130 140 150
VPFSLATTEK LLHMYDKNHS GEITFDEFKD LHHFILSMRE GFRKRDSSGD
160 170 180 190 200
GRLDSNEVRA ALLSSGYQVS EQTFQALMRK FDRQRRGSLG FDDYVELSIF
210 220 230
VCRVRNVFAF YDRERTGQVT FTFDTFIGGS VSIL
Length:234
Mass (Da):26,001
Last modified:July 19, 2005 - v1
Checksum:i156872D70DC6127A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FR796409 Genomic DNA. Translation: CAJ03147.1.
RefSeqiXP_001681890.1. XM_001681838.1.

Genome annotation databases

EnsemblProtistsiLmjF.13.1460:mRNA; LmjF.13.1460:pep; LmjF.13.1460.
GeneIDi5650175.
KEGGilma:LMJF_13_1460.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FR796409 Genomic DNA. Translation: CAJ03147.1.
RefSeqiXP_001681890.1. XM_001681838.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1Y1XX-ray1.95A/B53-234[»]
ProteinModelPortaliQ4QG08.
SMRiQ4QG08. Positions 53-234.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi5664.LmjF.13.1460.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiLmjF.13.1460:mRNA; LmjF.13.1460:pep; LmjF.13.1460.
GeneIDi5650175.
KEGGilma:LMJF_13_1460.

Phylogenomic databases

eggNOGiKOG0037. Eukaryota.
ENOG410YKQK. LUCA.
HOGENOMiHOG000256123.
InParanoidiQ4QG08.
OMAiIHHPGAY.

Miscellaneous databases

EvolutionaryTraceiQ4QG08.

Family and domain databases

Gene3Di1.10.238.10. 1 hit.
InterProiIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
[Graphical view]
PfamiPF13499. EF-hand_7. 2 hits.
[Graphical view]
SMARTiSM00054. EFh. 3 hits.
[Graphical view]
SUPFAMiSSF47473. SSF47473. 1 hit.
PROSITEiPS00018. EF_HAND_1. 3 hits.
PS50222. EF_HAND_2. 4 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Structural analysis of a homolog of programmed cell death 6 protein from Leishmania major Friedlin."
    Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
    Robien M.A., Hol W.G.J.
    Submitted (NOV-2004) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.95 ANGSTROMS) OF 53-234 IN COMPLEX WITH CALCIUM.
  2. "The genome of the kinetoplastid parasite, Leishmania major."
    Ivens A.C., Peacock C.S., Worthey E.A., Murphy L., Aggarwal G., Berriman M., Sisk E., Rajandream M.A., Adlem E., Aert R., Anupama A., Apostolou Z., Attipoe P., Bason N., Bauser C., Beck A., Beverley S.M., Bianchettin G.
    , Borzym K., Bothe G., Bruschi C.V., Collins M., Cadag E., Ciarloni L., Clayton C., Coulson R.M., Cronin A., Cruz A.K., Davies R.M., De Gaudenzi J., Dobson D.E., Duesterhoeft A., Fazelina G., Fosker N., Frasch A.C., Fraser A., Fuchs M., Gabel C., Goble A., Goffeau A., Harris D., Hertz-Fowler C., Hilbert H., Horn D., Huang Y., Klages S., Knights A., Kube M., Larke N., Litvin L., Lord A., Louie T., Marra M., Masuy D., Matthews K., Michaeli S., Mottram J.C., Muller-Auer S., Munden H., Nelson S., Norbertczak H., Oliver K., O'neil S., Pentony M., Pohl T.M., Price C., Purnelle B., Quail M.A., Rabbinowitsch E., Reinhardt R., Rieger M., Rinta J., Robben J., Robertson L., Ruiz J.C., Rutter S., Saunders D., Schafer M., Schein J., Schwartz D.C., Seeger K., Seyler A., Sharp S., Shin H., Sivam D., Squares R., Squares S., Tosato V., Vogt C., Volckaert G., Wambutt R., Warren T., Wedler H., Woodward J., Zhou S., Zimmermann W., Smith D.F., Blackwell J.M., Stuart K.D., Barrell B., Myler P.J.
    Science 309:436-442(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MHOM/IL/81/FriedlinImported.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MHOM/IL/81/FriedlinImported.

Entry informationi

Entry nameiQ4QG08_LEIMA
AccessioniPrimary (citable) accession number: Q4QG08
Entry historyi
Integrated into UniProtKB/TrEMBL: July 19, 2005
Last sequence update: July 19, 2005
Last modified: March 16, 2016
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.