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Protein

Ubiquitin-fold modifier-conjugating enzyme 1

Gene

LMJF_15_1250

Organism
Leishmania major
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei115 – 1151Glycyl thioester intermediateUniRule annotation

Keywords - Biological processi

Ubl conjugation pathwayUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Ubiquitin-fold modifier-conjugating enzyme 1UniRule annotation
Gene namesi
ORF Names:LMJF_15_1250Imported
OrganismiLeishmania majorImported
Taxonomic identifieri5664 [NCBI]
Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeLeishmaniinaeLeishmania
Proteomesi
  • UP000000542 Componenti: Chromosome 15

Interactioni

Protein-protein interaction databases

STRINGi5664.LmjF.15.1250.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3KPAX-ray2.20A/B/C1-160[»]
ProteinModelPortaliQ4QF57.
SMRiQ4QF57. Positions 2-159.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ4QF57.

Family & Domainsi

Sequence similaritiesi

Belongs to the ubiquitin-conjugating enzyme family. UFC1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG3357. Eukaryota.
ENOG410ZBCX. LUCA.
HOGENOMiHOG000243361.
InParanoidiQ4QF57.
KOiK12165.
OMAiEHFKPLW.

Family and domain databases

Gene3Di3.10.110.10. 1 hit.
InterProiIPR016135. UBQ-conjugating_enzyme/RWD.
IPR014806. Ufc1.
[Graphical view]
PANTHERiPTHR12921. PTHR12921. 1 hit.
PfamiPF08694. UFC1. 1 hit.
[Graphical view]
PIRSFiPIRSF008716. DUF1782. 1 hit.
SUPFAMiSSF54495. SSF54495. 1 hit.

Sequencei

Sequence statusi: Complete.

Q4QF57-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEPSVKESVS RIPLLKTKAG PRDGDKWTAR LKEEYASLIT YVEHNKASDS
60 70 80 90 100
HWFHLESNPQ GTRWYGTCWT YYKNEKYEFE MNFDIPVTYP QAPPEIALPE
110 120 130 140 150
LEGKTVKMYR GGKICMTTHF FPLWARNVPY FGISHVLALG LGPWLSIEVP
160 170
AIVEEGYLKP ASAATVPTTG E
Length:171
Mass (Da):19,442
Last modified:July 19, 2005 - v1
Checksum:i49A962F64107B823
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FR796411 Genomic DNA. Translation: CAJ03353.1.
RefSeqiXP_001682041.1. XM_001681989.1.

Genome annotation databases

EnsemblProtistsiLmjF.15.1250:mRNA; LmjF.15.1250:pep; LmjF.15.1250.
GeneIDi5650508.
KEGGilma:LMJF_15_1250.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FR796411 Genomic DNA. Translation: CAJ03353.1.
RefSeqiXP_001682041.1. XM_001681989.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3KPAX-ray2.20A/B/C1-160[»]
ProteinModelPortaliQ4QF57.
SMRiQ4QF57. Positions 2-159.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi5664.LmjF.15.1250.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiLmjF.15.1250:mRNA; LmjF.15.1250:pep; LmjF.15.1250.
GeneIDi5650508.
KEGGilma:LMJF_15_1250.

Phylogenomic databases

eggNOGiKOG3357. Eukaryota.
ENOG410ZBCX. LUCA.
HOGENOMiHOG000243361.
InParanoidiQ4QF57.
KOiK12165.
OMAiEHFKPLW.

Miscellaneous databases

EvolutionaryTraceiQ4QF57.

Family and domain databases

Gene3Di3.10.110.10. 1 hit.
InterProiIPR016135. UBQ-conjugating_enzyme/RWD.
IPR014806. Ufc1.
[Graphical view]
PANTHERiPTHR12921. PTHR12921. 1 hit.
PfamiPF08694. UFC1. 1 hit.
[Graphical view]
PIRSFiPIRSF008716. DUF1782. 1 hit.
SUPFAMiSSF54495. SSF54495. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ4QF57_LEIMA
AccessioniPrimary (citable) accession number: Q4QF57
Entry historyi
Integrated into UniProtKB/TrEMBL: July 19, 2005
Last sequence update: July 19, 2005
Last modified: March 16, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.