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Protein
Submitted name:

Cytochrome c

Gene

LMJF_16_1310

Organism
Leishmania major
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei28 – 281Heme (covalent)Combined sources
Metal bindingi29 – 291Iron (heme axial ligand); via tele nitrogenCombined sources
Metal bindingi91 – 911Iron (heme axial ligand)Combined sources

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Electron transport, Respiratory chainUniRule annotation, Transport

Keywords - Ligandi

HemeUniRule annotationCombined sources, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome cImported
Submitted name:
Putative cytochrome cImported
Gene namesi
ORF Names:LMJF_16_1310Imported, LMJF_16_1320Imported
OrganismiLeishmania majorImported
Taxonomic identifieri5664 [NCBI]
Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeLeishmaniinaeLeishmania
Proteomesi
  • UP000000542 Componenti: Chromosome 16

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

MitochondrionUniRule annotation

PTM / Processingi

Post-translational modificationi

Binds 1 heme group per subunit.UniRule annotation

Interactioni

Protein-protein interaction databases

DIPiDIP-60329N.
STRINGi5664.LmjF.16.1320.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4DY9X-ray2.08A1-113[»]
4GEDX-ray1.84B1-113[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini12 – 113102Cytochrome cInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the cytochrome c family.UniRule annotation

Phylogenomic databases

eggNOGiKOG3453. Eukaryota.
COG3474. LUCA.
HOGENOMiHOG000009762.
KOiK08738.
OMAiWNEETLM.

Family and domain databases

Gene3Di1.10.760.10. 1 hit.
InterProiIPR009056. Cyt_c-like_dom.
IPR002327. Cyt_c_1A/1B.
[Graphical view]
PANTHERiPTHR11961. PTHR11961. 1 hit.
PfamiPF00034. Cytochrom_C. 1 hit.
[Graphical view]
PRINTSiPR00604. CYTCHRMECIAB.
SUPFAMiSSF46626. SSF46626. 1 hit.
PROSITEiPS51007. CYTC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4QEN5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPPKARAPLP PGDVERGEKL FKGRAAQCHT ATKGGSNGVG PNLFGIVNRP
60 70 80 90 100
SGKVEGFTYS KANAESGVIW TPEVLDVYLE NPKKFMPGTK MSFAGIKKPQ
110
ERADVIAYLE TLK
Length:113
Mass (Da):12,188
Last modified:July 19, 2005 - v1
Checksum:iBC43840926FF0405
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY971584 mRNA. Translation: AAY40864.1.
FR796412 Genomic DNA. Translation: CAJ04011.1.
FR796412 Genomic DNA. Translation: CAJ04013.1.
RefSeqiXP_001682212.1. XM_001682160.1.
XP_001682213.1. XM_001682161.1.

Genome annotation databases

EnsemblProtistsiLmjF.16.1310:mRNA; LmjF.16.1310:pep; LmjF.16.1310.
LmjF.16.1320:mRNA; LmjF.16.1320:pep; LmjF.16.1320.
GeneIDi5650682.
5650683.
KEGGilma:LMJF_16_1310.
lma:LMJF_16_1320.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY971584 mRNA. Translation: AAY40864.1.
FR796412 Genomic DNA. Translation: CAJ04011.1.
FR796412 Genomic DNA. Translation: CAJ04013.1.
RefSeqiXP_001682212.1. XM_001682160.1.
XP_001682213.1. XM_001682161.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4DY9X-ray2.08A1-113[»]
4GEDX-ray1.84B1-113[»]
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-60329N.
STRINGi5664.LmjF.16.1320.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiLmjF.16.1310:mRNA; LmjF.16.1310:pep; LmjF.16.1310.
LmjF.16.1320:mRNA; LmjF.16.1320:pep; LmjF.16.1320.
GeneIDi5650682.
5650683.
KEGGilma:LMJF_16_1310.
lma:LMJF_16_1320.

Phylogenomic databases

eggNOGiKOG3453. Eukaryota.
COG3474. LUCA.
HOGENOMiHOG000009762.
KOiK08738.
OMAiWNEETLM.

Family and domain databases

Gene3Di1.10.760.10. 1 hit.
InterProiIPR009056. Cyt_c-like_dom.
IPR002327. Cyt_c_1A/1B.
[Graphical view]
PANTHERiPTHR11961. PTHR11961. 1 hit.
PfamiPF00034. Cytochrom_C. 1 hit.
[Graphical view]
PRINTSiPR00604. CYTCHRMECIAB.
SUPFAMiSSF46626. SSF46626. 1 hit.
PROSITEiPS51007. CYTC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ4QEN5_LEIMA
AccessioniPrimary (citable) accession number: Q4QEN5
Secondary accession number(s): A0PJ38
Entry historyi
Integrated into UniProtKB/TrEMBL: July 19, 2005
Last sequence update: July 19, 2005
Last modified: September 7, 2016
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.