Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Cytochrome c

Gene

LMJF_16_1310

Organism
Leishmania major
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei28Heme (covalent)Combined sources1
Metal bindingi29Iron (heme axial ligand); via tele nitrogenCombined sources1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processElectron transport, Respiratory chainUniRule annotation, Transport
LigandHemePROSITE-ProRule annotationCombined sources, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome cImported
Submitted name:
Putative cytochrome cImported
Gene namesi
ORF Names:LMJF_16_1310Imported, LMJF_16_1320Imported
OrganismiLeishmania majorImported
Taxonomic identifieri5664 [NCBI]
Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeLeishmaniinaeLeishmania
Proteomesi

Organism-specific databases

EuPathDBiTriTrypDB:LmjF.16.1310
TriTrypDB:LmjF.16.1320

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

MitochondrionUniRule annotation

PTM / Processingi

Post-translational modificationi

Binds 1 heme group per subunit.UniRule annotation

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
APXQ4Q3K22EBI-16019427,EBI-16019391

Protein-protein interaction databases

DIPiDIP-60329N
IntActiQ4QEN5, 1 interactor
STRINGi5664.LmjF.16.1320

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4DY9X-ray2.08A1-113[»]
4GEDX-ray1.84B1-113[»]
SMRiQ4QEN5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 113Cytochrome cInterPro annotationAdd BLAST102

Sequence similaritiesi

Belongs to the cytochrome c family.UniRule annotation

Phylogenomic databases

eggNOGiKOG3453 Eukaryota
COG3474 LUCA
HOGENOMiHOG000009762
KOiK08738
OMAiGLFKTRC

Family and domain databases

Gene3Di1.10.760.10, 1 hit
InterProiView protein in InterPro
IPR009056 Cyt_c-like_dom
IPR036909 Cyt_c-like_dom_sf
IPR002327 Cyt_c_1A/1B
PANTHERiPTHR11961 PTHR11961, 1 hit
PfamiView protein in Pfam
PF00034 Cytochrom_C, 1 hit
PRINTSiPR00604 CYTCHRMECIAB
SUPFAMiSSF46626 SSF46626, 1 hit
PROSITEiView protein in PROSITE
PS51007 CYTC, 1 hit

Sequencei

Sequence statusi: Complete.

Q4QEN5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPPKARAPLP PGDVERGEKL FKGRAAQCHT ATKGGSNGVG PNLFGIVNRP
60 70 80 90 100
SGKVEGFTYS KANAESGVIW TPEVLDVYLE NPKKFMPGTK MSFAGIKKPQ
110
ERADVIAYLE TLK
Length:113
Mass (Da):12,188
Last modified:July 19, 2005 - v1
Checksum:iBC43840926FF0405
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY971584 mRNA Translation: AAY40864.1
FR796412 Genomic DNA Translation: CAJ04011.1
FR796412 Genomic DNA Translation: CAJ04013.1
RefSeqiXP_001682212.1, XM_001682160.1
XP_001682213.1, XM_001682161.1

Genome annotation databases

EnsemblProtistsiLmjF.16.1310:mRNA; LmjF.16.1310:pep; LmjF.16.1310
LmjF.16.1320:mRNA; LmjF.16.1320:pep; LmjF.16.1320
GeneDBiLmjF.16.1310:pep
LmjF.16.1320:pep
GeneIDi5650682
5650683
KEGGilma:LMJF_16_1310
lma:LMJF_16_1320

Entry informationi

Entry nameiQ4QEN5_LEIMA
AccessioniPrimary (citable) accession number: Q4QEN5
Secondary accession number(s): A0PJ38
Entry historyiIntegrated into UniProtKB/TrEMBL: July 19, 2005
Last sequence update: July 19, 2005
Last modified: May 23, 2018
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health