Q4QE43 (Q4QE43_LEIMA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Ferrochelatase-like protein EMBL CAJ04190.1
EC=4.99.1.1 EMBL CAJ04190.1

Gene names

ORF Names:

LMJF_17_1460 EMBL CAJ04190.1

Organism

Leishmania major

Taxonomic identifier

5664 [NCBI]

Taxonomic lineage

Eukaryota › Euglenozoa › Kinetoplastida › Trypanosomatidae › Leishmania

Protein attributes

Sequence length	385 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the ferrochelatase family. RuleBase RU004185

Ontologies

Keywords
Molecular function	Lyase EMBL CAJ04190.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	heme biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	ferrochelatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q4QE43 [UniParc]. Last modified July 19, 2005. Version 1. Checksum: FA3A9FA52BC33495	FASTA	385	42,260
	10 20 30 40 50 60 MSCAPGPTKA ILLVNLGTTT APTAPAVRRF LREFLSDRRV IDVPRFLWYS ALYGFILPFR 70 80 90 100 110 120 PRRITPLYKG IWIKSDSGVV INGKTEGSPL TLYSESLVAK VQASVEKTSG GAVVARHAMR 130 140 150 160 170 180 YGVNNIPSTL KALHDEFATL RELVVLPLFP QYTSTTSASI YDEVFKFYTD TQRRSIPSLR 190 200 210 220 230 240 TIRDYAEHPV YVEALGSSLL SSIKAHVTAK AGAAKDWKSA LADQLPEIGI IITYHSIPVR 250 260 270 280 290 300 YVEEHDDYPQ RCEATTAAIK AYIEAESGIS LSDCLVHVYQ SQFGNQPWLG PTLNAAATAF 310 320 330 340 350 360 PLPPHDARKQ AFSDAHRNKA LLTKQATICF AMAPGFAVDC VETLSEIERE AGEVFKQSGG 370 380 HKLIYVPCLN DSDTHVKVLT SVVGA

References

[1]

"The genome of the kinetoplastid parasite, Leishmania major." Ivens A.C., Peacock C.S., Worthey E.A., Murphy L., Aggarwal G., Berriman M., Sisk E., Rajandream M.A., Adlem E., Aert R., Anupama A., Apostolou Z., Attipoe P., Bason N., Bauser C., Beck A., Beverley S.M., Bianchettin G. , Borzym K., Bothe G., Bruschi C.V., Collins M., Cadag E., Ciarloni L., Clayton C., Coulson R.M.R., Cronin A., Cruz A.K., Davies R.M., De Gaudenzi J., Dobson D.E., Duesterhoeft A., Fazelina G., Fosker N., Frasch A.C., Fraser A., Fuchs M., Gabel C., Goble A., Goffeau A., Harris D., Hertz-Fowler C., Hilbert H., Horn D., Huang Y., Klages S., Knights A., Kube M., Larke N., Litvin L., Lord A., Louie T., Marra M., Masuy D., Matthews K., Michaeli S., Mottram J.C., Mueller-Auer S., Munden H., Nelson S., Norbertczak H., Oliver K., O'neil S., Pentony M., Pohl T.M., Price C., Purnelle B., Quail M.A., Rabbinowitsch E., Reinhardt R., Rieger M., Rinta J., Robben J., Robertson L., Ruiz J.C., Rutter S., Saunders D., Schaefer M., Schein J., Schwartz D.C., Seeger K., Seyler A., Sharp S., Shin H., Sivam D., Squares R., Squares S., Tosato V., Vogt C., Volckaert G., Wambutt R., Warren T., Wedler H., Woodward J., Zhou S., Zimmermann W., Smith D.F., Blackwell J.M., Stuart K.D., Barrell B.G., Myler P.J. Science 309:436-442(2005) [PubMed: 16020728] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MHOM/IL/81/Friedlin.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FR796413 Genomic DNA. Translation: CAJ04190.1.
RefSeq	XP_001682405.1. XM_001682353.1.
3D structure databases
ProteinModelPortal	Q4QE43.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblProtists	LmjF.17.1460:mRNA; LmjF.17.1460:pep; LmjF.17.1460.
GeneID	5650879.
KEGG	lma:LmjF17.1460.
Organism-specific databases
EuPathDB	EupathDB:LmjF.17.1460.
Phylogenomic databases
HOGENOM	HBG697135.
OMA	TIEEIGM.
PhylomeDB	Q4QE43.
ProtClustDB	CLSZ2456097.
Family and domain databases
HAMAP	MF_00323. Ferrochelatase. [Tree]
InterPro	IPR001015. Ferrochelatase. [Graphical view]
KO	K01772.
PANTHER	PTHR11108. Ferrochelatase. 1 hit.
Pfam	PF00762. Ferrochelatase. 2 hits. [Graphical view]
TIGRFAMs	TIGR00109. HemH. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q4QE43_LEIMA

Accession

Primary (citable) accession number: Q4QE43

Entry history

Integrated into UniProtKB/TrEMBL:	July 19, 2005
Last sequence update:	July 19, 2005
Last modified:	December 14, 2011
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)