Q4Q8W9 (Q4Q8W9_LEIMA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative GDP-mannose 4,6 dehydratase EMBL CAJ05556.1
EC=4.2.1.46 EMBL CAJ05556.1

Gene names

ORF Names:

LMJF_26_2230 EMBL CAJ05556.1

Organism

Leishmania major [Reference proteome]

Taxonomic identifier

5664 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Euglenozoa › Kinetoplastida › Trypanosomatidae › Leishmaniinae › Leishmania › Leishmania › Leishmania major species complex

Protein attributes

Sequence length	446 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Lyase EMBL CAJ05556.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	nucleotide-sugar metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	coenzyme binding Inferred from electronic annotation. Source: InterPro dTDP-glucose 4,6-dehydratase activity Inferred from electronic annotation. Source: EC nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q4Q8W9 [UniParc]. Last modified July 19, 2005. Version 1. Checksum: 2901C410E1A5BBA8	FASTA	446	47,856
	10 20 30 40 50 60 MPLNGTAGAG AGVPSPSAHP QAGIASCTRN GTTGLTEHPA VLTAHGDAHA RDLLQHLPGH 70 80 90 100 110 120 RILVTGGCGF IGSAFIRHLL MYAPASVHVF NLDTVEYCAG VDAVLGPLAA TRDDDRAAAC 130 140 150 160 170 180 SGASVSEDAN GTVASCSLSC DVSPVSRYHF IAGSILDATL VLHSLRTHHI DIIVHMAAQT 190 200 210 220 230 240 HVDHSFSRSV LFTQVNVVGT HTLLECARQY GQLTRFLHMS TDEVYGEVPA TARPANEAST 250 260 270 280 290 300 VLCPTNPYAA TKAAAEHLVS AYYHSFKLPV LISRGNNAFG PGQYPEKVIP SFIVHALRRE 310 320 330 340 350 360 RLPIHGDGHH QRRFIYVDDV ARALCTILVR GGVGEVYNVA SEREFSVHEV AQRVVACVAG 370 380 390 400 410 420 DDHDKVIAAS RADFDASYVR YVADRAYNDA RYCTESEKLA ALGWALEVSF EEGLRRTVAW 430 440 YRRHPLKAGG YWRGASEAGA TAPCSD

References

[1]

"The genome of the kinetoplastid parasite, Leishmania major." Ivens A.C., Peacock C.S., Worthey E.A., Murphy L., Aggarwal G., Berriman M., Sisk E., Rajandream M.A., Adlem E., Aert R., Anupama A., Apostolou Z., Attipoe P., Bason N., Bauser C., Beck A., Beverley S.M., Bianchettin G. , Borzym K., Bothe G., Bruschi C.V., Collins M., Cadag E., Ciarloni L., Clayton C., Coulson R.M.R., Cronin A., Cruz A.K., Davies R.M., De Gaudenzi J., Dobson D.E., Duesterhoeft A., Fazelina G., Fosker N., Frasch A.C., Fraser A., Fuchs M., Gabel C., Goble A., Goffeau A., Harris D., Hertz-Fowler C., Hilbert H., Horn D., Huang Y., Klages S., Knights A., Kube M., Larke N., Litvin L., Lord A., Louie T., Marra M., Masuy D., Matthews K., Michaeli S., Mottram J.C., Mueller-Auer S., Munden H., Nelson S., Norbertczak H., Oliver K., O'neil S., Pentony M., Pohl T.M., Price C., Purnelle B., Quail M.A., Rabbinowitsch E., Reinhardt R., Rieger M., Rinta J., Robben J., Robertson L., Ruiz J.C., Rutter S., Saunders D., Schaefer M., Schein J., Schwartz D.C., Seeger K., Seyler A., Sharp S., Shin H., Sivam D., Squares R., Squares S., Tosato V., Vogt C., Volckaert G., Wambutt R., Warren T., Wedler H., Woodward J., Zhou S., Zimmermann W., Smith D.F., Blackwell J.M., Stuart K.D., Barrell B.G., Myler P.J. Science 309:436-442(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MHOM/IL/81/Friedlin.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FR796422 Genomic DNA. Translation: CAJ05556.1.
RefSeq	XP_001684229.1. XM_001684177.1.
3D structure databases
ProteinModelPortal	Q4Q8W9.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblProtists	LmjF.26.2230:mRNA; LmjF.26.2230:pep; LmjF.26.2230.
GeneID	5653152.
KEGG	lma:LMJF_26_2230.
Phylogenomic databases
HOGENOM	HOG000168006.
KO	K01710.
OMA	AYNDARY.
ProtClustDB	CLSZ2430684.
Family and domain databases
Gene3D	3.40.50.720. 2 hits.
InterPro	IPR005888. dTDP_Gluc_deHydtase. IPR001509. Epimerase_deHydtase. IPR016040. NAD(P)-bd_dom. [Graphical view]
PANTHER	PTHR10366:SF41. PTHR10366:SF41. 1 hit.
Pfam	PF01370. Epimerase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q4Q8W9_LEIMA

Accession

Primary (citable) accession number: Q4Q8W9

Entry history

Integrated into UniProtKB/TrEMBL:	July 19, 2005
Last sequence update:	July 19, 2005
Last modified:	April 3, 2013
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)