Q4Q6Y2 (Q4Q6Y2_LEIMA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative homoserine kinase EMBL CAJ06720.1
EC=2.7.1.39 EMBL CAJ06720.1

Gene names

ORF Names:

LMJF_30_3080 EMBL CAJ06720.1

Organism

Leishmania major

Taxonomic identifier

5664 [NCBI]

Taxonomic lineage

Eukaryota › Euglenozoa › Kinetoplastida › Trypanosomatidae › Leishmania

Protein attributes

Sequence length	341 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the GHMP kinase family. RuleBase RU004209

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU003563 Nucleotide-binding
Molecular function	Kinase RuleBase RU003563 EMBL CAJ06720.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	threonine metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW homoserine kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q4Q6Y2 [UniParc]. Last modified July 19, 2005. Version 1. Checksum: DD2ED93221FDD265	FASTA	341	36,396
	10 20 30 40 50 60 MSDEAAKPLP EKVSLRVPAT TANIGPAYDT LGMALSIFME LTVELAEAFS MTVTGEGQEH 70 80 90 100 110 120 ISTGEDNMVV QTCRIAFEEY AHKSMPPLKF TMHNNIPYKC GCGSSSAAAV AGFVAGMMLS 130 140 150 160 170 180 GLTLETHNSE SLLSAISKIE GHSDNAAPAI YGGIQLVYKK DDGRTMTYHV PTPPNLSIVL 190 200 210 220 230 240 FVPHKLMKAS THVTRELVPT AVSLRDAVHN ISGTAILTLA LSTGDLRMLK DASDCLHEQQ 250 260 270 280 290 300 RSRKLYPHYS ACAKAAREAG AEYAFLSGAG PSVCAMVSGR HGDLLTQPME ERKAEMVAEA 310 320 330 340 MVKAAEAVGV QGRVIITMPS DVGVHLSGTT CIRPNIQYTS I

References

[1]

"The genome of the kinetoplastid parasite, Leishmania major." Ivens A.C., Peacock C.S., Worthey E.A., Murphy L., Aggarwal G., Berriman M., Sisk E., Rajandream M.A., Adlem E., Aert R., Anupama A., Apostolou Z., Attipoe P., Bason N., Bauser C., Beck A., Beverley S.M., Bianchettin G. , Borzym K., Bothe G., Bruschi C.V., Collins M., Cadag E., Ciarloni L., Clayton C., Coulson R.M.R., Cronin A., Cruz A.K., Davies R.M., De Gaudenzi J., Dobson D.E., Duesterhoeft A., Fazelina G., Fosker N., Frasch A.C., Fraser A., Fuchs M., Gabel C., Goble A., Goffeau A., Harris D., Hertz-Fowler C., Hilbert H., Horn D., Huang Y., Klages S., Knights A., Kube M., Larke N., Litvin L., Lord A., Louie T., Marra M., Masuy D., Matthews K., Michaeli S., Mottram J.C., Mueller-Auer S., Munden H., Nelson S., Norbertczak H., Oliver K., O'neil S., Pentony M., Pohl T.M., Price C., Purnelle B., Quail M.A., Rabbinowitsch E., Reinhardt R., Rieger M., Rinta J., Robben J., Robertson L., Ruiz J.C., Rutter S., Saunders D., Schaefer M., Schein J., Schwartz D.C., Seeger K., Seyler A., Sharp S., Shin H., Sivam D., Squares R., Squares S., Tosato V., Vogt C., Volckaert G., Wambutt R., Warren T., Wedler H., Woodward J., Zhou S., Zimmermann W., Smith D.F., Blackwell J.M., Stuart K.D., Barrell B.G., Myler P.J. Science 309:436-442(2005) [PubMed: 16020728] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MHOM/IL/81/Friedlin.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FR796426 Genomic DNA. Translation: CAJ06720.1.
RefSeq	XP_001684916.1. XM_001684864.1.
3D structure databases
ProteinModelPortal	Q4Q6Y2.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblProtists	LmjF.30.3080:mRNA; LmjF.30.3080:pep; LmjF.30.3080.
GeneID	5653857.
KEGG	lma:LmjF30.3080.
Organism-specific databases
EuPathDB	EupathDB:LmjF.30.3080.
Phylogenomic databases
HOGENOM	HBG646290.
OMA	RSYDPLE.
PhylomeDB	Q4Q6Y2.
ProtClustDB	PTZ00299.
Family and domain databases
InterPro	IPR006204. GHMP_kinase. IPR013750. GHMP_kinase_C. IPR000870. Homoserine_kinase. IPR020568. Ribosomal_S5_D2-typ_fold. IPR014721. Ribosomal_S5_D2-typ_fold_subgr. [Graphical view]
Gene3D	G3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit.
KO	K00872.
Pfam	PF08544. GHMP_kinases_C. 1 hit. PF00288. GHMP_kinases_N. 1 hit. [Graphical view]
PIRSF	PIRSF000676. Homoser_kin. 1 hit.
PRINTS	PR00958. HOMSERKINASE.
SUPFAM	SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit.
TIGRFAMs	TIGR00191. ThrB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q4Q6Y2_LEIMA

Accession

Primary (citable) accession number: Q4Q6Y2

Entry history

Integrated into UniProtKB/TrEMBL:	July 19, 2005
Last sequence update:	July 19, 2005
Last modified:	November 16, 2011
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)