ID   AGL61_ARATH             Reviewed;         264 AA.
AC   Q4PSU4; Q9SK48;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   16-JUN-2009, entry version 26.
DE   RecName: Full=Agamous-like MADS-box protein AGL61;
DE   AltName: Full=Protein DIANA;
GN   Name=AGL61; Synonyms=DIA; OrderedLocusNames=At2g24840;
GN   ORFNames=F27C12.24;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons;
OC   rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   MEDLINE=20083487; PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L.,
RA   Moffat K.S., Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L.,
RA   Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H.,
RA   Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D.,
RA   Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M.,
RA   Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis
RT   thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RA   Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W.,
RA   Redman J.C., Wu H.C., Utterback T., Town C.D.;
RL   Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 39-264, FUNCTION, SUBUNIT, SUBCELLULAR
RP   LOCATION, TISSUE SPECIFICITY, AND INTERACTION WITH AGL80.
RX   PubMed=18599653; DOI=10.1104/pp.108.119404;
RA   Steffen J.G., Kang I.-H., Portereiko M.F., Lloyd A., Drews G.N.;
RT   "AGL61 interacts with AGL80 and is required for central cell
RT   development in Arabidopsis.";
RL   Plant Physiol. 148:259-268(2008).
RN   [4]
RP   FUNCTION, INTERACTION WITH AGL80; AGL86; PHE1 AND PHE2, DEVELOPMENTAL
RP   STAGE, AND TISSUE SPECIFICITY.
RX   PubMed=18713950; DOI=10.1105/tpc.108.058958;
RA   Bemer M., Wolters-Arts M., Grossniklaus U., Angenent G.C.;
RT   "The MADS domain protein DIANA acts together with AGAMOUS-LIKE80 to
RT   specify the central cell in Arabidopsis ovules.";
RL   Plant Cell 20:2088-2101(2008).
CC   -!- FUNCTION: Probable transcription factor. Controls central cell
CC       differentiation during female gametophyte development.
CC   -!- SUBUNIT: Interacts with PHE1/AGL37, PHE2/AGL38, AGL80 and AGL86.
CC       Forms a heterodimer with AGL80.
CC   -!- INTERACTION:
CC       Q2V412:-; NbExp=1; IntAct=EBI-1237976, EBI-1238781;
CC       Q9FJK3:AGL80; NbExp=2; IntAct=EBI-1237976, EBI-622424;
CC       P62157:CALM (xeno); NbExp=1; IntAct=EBI-1237976, EBI-397403;
CC       P25854:CAM1; NbExp=1; IntAct=EBI-1237976, EBI-1235664;
CC       Q03509:CAM6; NbExp=1; IntAct=EBI-1237976, EBI-1236097;
CC       P59220:CAM7; NbExp=1; IntAct=EBI-1237976, EBI-1236031;
CC       P30187:CML10; NbExp=1; IntAct=EBI-1237976, EBI-1238722;
CC       O23320:CML8; NbExp=1; IntAct=EBI-1237976, EBI-1237764;
CC       Q9S744:CML9; NbExp=1; IntAct=EBI-1237976, EBI-1236048;
CC   -!- SUBCELLULAR LOCATION: Nucleus. Note=The transport to the nucleus
CC       is dependent on dimerization with AGL80.
CC   -!- TISSUE SPECIFICITY: Expressed exclusively in the central cell of
CC       the female gametophyte and in early endosperm.
CC   -!- DEVELOPMENTAL STAGE: Expressed in the final stages of embryo sac
CC       development.
CC   -!- MISCELLANEOUS: Plants lacking AGL61 show a reduced size of the
CC       central cell and a reduced or absent central cell vacuole. When
CC       fertilized, the central cell fails to give rise to endosperm and
CC       the embryo sac degenerates. However, mutated female gametophytesol
CC       are not defective in pollen tube guidance and the synergid
CC       function is not impaired.
CC   -!- MISCELLANEOUS: This protein was called 'DIANA' after the virginal
CC       Roman goddess of the hunt.
CC   -!- SIMILARITY: Contains 1 MADS-box domain.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAD23028.1; Type=Erroneous gene model prediction;
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DR   EMBL; AC006585; AAD23028.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; DQ056542; AAY78694.1; -; mRNA.
DR   EMBL; EU836691; ACF37253.1; ALT_INIT; mRNA.
DR   IPI; IPI00545091; -.
DR   PIR; B84641; B84641.
DR   RefSeq; NP_850058.1; -.
DR   UniGene; At.52900; -.
DR   IntAct; Q4PSU4; 12.
DR   GeneID; 817021; -.
DR   GenomeReviews; CT485783_GR; AT2G24840.
DR   KEGG; ath:AT2G24840; -.
DR   GeneFarm; 3717; 371.
DR   TAIR; At2g24840; -.
DR   GO; GO:0005634; C:nucleus; IDA:TAIR.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:transcription factor activity; IEA:InterPro.
DR   GO; GO:0009559; P:embryo sac central cell differentiation; IMP:TAIR.
DR   GO; GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
DR   GO; GO:0006350; P:transcription; IEA:UniProtKB-KW.
DR   InterPro; IPR002100; TF_MADSbox.
DR   Pfam; PF00319; SRF-TF; 1.
DR   PRINTS; PR00404; MADSDOMAIN.
DR   SMART; SM00432; MADS; 1.
DR   PROSITE; PS00350; MADS_BOX_1; FALSE_NEG.
DR   PROSITE; PS50066; MADS_BOX_2; 1.
PE   1: Evidence at protein level;
KW   Complete proteome; DNA-binding; Nucleus; Transcription;
KW   Transcription regulation.
FT   CHAIN         1    264       Agamous-like MADS-box protein AGL61.
FT                                /FTId=PRO_0000363649.
FT   DOMAIN       62    122       MADS-box.
SQ   SEQUENCE   264 AA;  30264 MW;  517BACA6BF7B4CDC CRC64;
     MYVTKYKNKL PTLQVDLIIM PHQTQACIYK QTLSLHQIFQ QRKATKTLHT KKTMMSKKKE
     SIGRQKIPMV KIKKESHRQV TFSKRRAGLF KKASELCTLC GAEIGIIVFS PAKKPFSFGH
     PSVESVLDRY VSRNNMSLAQ SQQLQGSPAA SCELNMQLTH ILSEVEEEKK KGQAMEEMRK
     ESVRRSMINW WEKPVEEMNM VQLQEMKYAL EELRKTVVTN MASFNEAKDD VFGFLDNKVT
     VPPYVNMPSG PSNIYNFANG NGCF
//