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Protein

Probable protein phosphatase 2C 71

Gene

At5g24940

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi69 – 691Manganese 1By similarity
Metal bindingi69 – 691Manganese 2By similarity
Metal bindingi70 – 701Manganese 1; via carbonyl oxygenBy similarity
Metal bindingi231 – 2311Manganese 2By similarity
Metal bindingi270 – 2701Manganese 2By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein serine/threonine phosphatase activity Source: InterPro

GO - Biological processi

  1. protein dephosphorylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Enzyme and pathway databases

BioCyciARA:AT5G24940-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 71 (EC:3.1.3.16)
Short name:
AtPP2C71
Gene namesi
Ordered Locus Names:At5g24940
ORF Names:F6A4.150
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 5

Organism-specific databases

TAIRiAT5G24940.

Subcellular locationi

GO - Cellular componenti

  1. apoplast Source: TAIR
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 447447Probable protein phosphatase 2C 71PRO_0000367991Add
BLAST

Proteomic databases

PaxDbiQ4PSE8.
PRIDEiQ4PSE8.

Expressioni

Gene expression databases

GenevestigatoriQ4PSE8.

Interactioni

Protein-protein interaction databases

BioGridi17839. 1 interaction.
IntActiQ4PSE8. 1 interaction.
MINTiMINT-8390648.
STRINGi3702.AT5G24940.1-P.

Structurei

3D structure databases

ProteinModelPortaliQ4PSE8.
SMRiQ4PSE8. Positions 34-277.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini60 – 272213PP2C-likeAdd
BLAST

Sequence similaritiesi

Belongs to the PP2C family.Curated
Contains 1 PP2C-like domain.Curated

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000233896.
InParanoidiQ4PSE8.
KOiK17506.
OMAiMRIVEAP.
PhylomeDBiQ4PSE8.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS01032. PP2C. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4PSE8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGYMDLALSY SNQMRIVEAP ASGGGLSQNG KFSYGYASSA GKRSSMEDFF
60 70 80 90 100
ETRIDGIDGE IVGLFGVFDG HGGSRAAEYV KRHLFSNLIT HPKFISDTKS
110 120 130 140 150
AIADAYTHTD SELLKSENSH TRDAGSTAST AILVGDRLLV ANVGDSRAVI
160 170 180 190 200
CRGGNAFAVS RDHKPDQSDE RERIENAGGF VMWAGTWRVG GVLAVSRAFG
210 220 230 240 250
DRLLKQYVVA DPEIQEEKID DSLEFLILAS DGLWDVFSNE EAVAVVKEVE
260 270 280 290 300
DPEESTKKLV GEAIKRGSAD NITCVVVRFL ESKSANNNGS SSSEEANQVP
310 320 330 340 350
TAVRNDSDHK ISAKETNQDH TTVNKDLDRN TDSQSLNQKP IAARSADNSN
360 370 380 390 400
QKPIATTATG HSVSSEQSGL TGEKSQMPIK IRSDSEPKSS AKVPNQTQST
410 420 430 440
VHNDLDSSTA KKPAATEQSG STGERNRKPI KVHSDSAARK TTPSIFN
Length:447
Mass (Da):48,120
Last modified:July 19, 2005 - v1
Checksum:iB3BB13D43A2A6939
GO

Sequence cautioni

The sequence BAC42678.1 differs from that shown.Intron retention.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF069716 Genomic DNA. No translation available.
CP002688 Genomic DNA. Translation: AED93380.1.
AK118047 mRNA. Translation: BAC42678.1. Sequence problems.
DQ056688 mRNA. Translation: AAY78834.1.
RefSeqiNP_197876.1. NM_122403.1.
UniGeneiAt.54985.

Genome annotation databases

EnsemblPlantsiAT5G24940.1; AT5G24940.1; AT5G24940.
GeneIDi832564.
KEGGiath:AT5G24940.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF069716 Genomic DNA. No translation available.
CP002688 Genomic DNA. Translation: AED93380.1.
AK118047 mRNA. Translation: BAC42678.1. Sequence problems.
DQ056688 mRNA. Translation: AAY78834.1.
RefSeqiNP_197876.1. NM_122403.1.
UniGeneiAt.54985.

3D structure databases

ProteinModelPortaliQ4PSE8.
SMRiQ4PSE8. Positions 34-277.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi17839. 1 interaction.
IntActiQ4PSE8. 1 interaction.
MINTiMINT-8390648.
STRINGi3702.AT5G24940.1-P.

Proteomic databases

PaxDbiQ4PSE8.
PRIDEiQ4PSE8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT5G24940.1; AT5G24940.1; AT5G24940.
GeneIDi832564.
KEGGiath:AT5G24940.

Organism-specific databases

TAIRiAT5G24940.

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000233896.
InParanoidiQ4PSE8.
KOiK17506.
OMAiMRIVEAP.
PhylomeDBiQ4PSE8.

Enzyme and pathway databases

BioCyciARA:AT5G24940-MONOMER.

Gene expression databases

GenevestigatoriQ4PSE8.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS01032. PP2C. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana."
    Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E., Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.
    , Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L., O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D., Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M., Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L., Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B., Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P., Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M., Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D., Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A., Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I., Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T., Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A., McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U., Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G., Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W., Bevan M., Fransz P.F.
    Nature 408:823-826(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  4. Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W., Redman J.C., Wu H.C., Utterback T., Town C.D.
    Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  5. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
    Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
    BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiP2C71_ARATH
AccessioniPrimary (citable) accession number: Q4PSE8
Secondary accession number(s): Q8GTR8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: July 19, 2005
Last modified: January 7, 2015
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.