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Protein

Iron-sulfur clusters transporter ATM1, mitochondrial

Gene

ATM1

Organism
Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Performs an essential function in the generation of cytoplasmic iron-sulfur proteins by mediating the ATP-dependent export of Fe/S cluster precursors synthesized by NFS1 and other mitochondrial proteins. Hydrolyzes ATP. Binds glutathione and may function by transporting a glutathione-conjugated iron-sulfur compound (By similarity).By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei455Glutathione; via amide nitrogenBy similarity1
Binding sitei506ATPBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi530 – 541ATPPROSITE-ProRule annotationAdd BLAST12

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processIon transport, Iron transport, Transport
LigandATP-binding, Iron, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Iron-sulfur clusters transporter ATM1, mitochondrial
Gene namesi
Name:ATM1
ORF Names:UMAG_00597
OrganismiUstilago maydis (strain 521 / FGSC 9021) (Corn smut fungus)
Taxonomic identifieri237631 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaUstilaginomycotinaUstilaginomycetesUstilaginalesUstilaginaceaeUstilago
Proteomesi
  • UP000000561 Componentsi: Chromosome 1, Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:UMAG_00597.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini45 – 167Mitochondrial matrixBy similarityAdd BLAST123
Transmembranei168 – 189HelicalPROSITE-ProRule annotationAdd BLAST22
Topological domaini190 – 217Mitochondrial intermembraneBy similarityAdd BLAST28
Transmembranei218 – 241HelicalPROSITE-ProRule annotationAdd BLAST24
Topological domaini242 – 290Mitochondrial matrixBy similarityAdd BLAST49
Transmembranei291 – 314HelicalPROSITE-ProRule annotationAdd BLAST24
Topological domaini315Mitochondrial intermembraneBy similarity1
Transmembranei316 – 336HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini337 – 402Mitochondrial matrixBy similarityAdd BLAST66
Transmembranei403 – 421HelicalPROSITE-ProRule annotationAdd BLAST19
Topological domaini422 – 436Mitochondrial intermembraneBy similarityAdd BLAST15
Transmembranei437 – 458HelicalPROSITE-ProRule annotationAdd BLAST22
Topological domaini459 – 763Mitochondrial matrixBy similarityAdd BLAST305

GO - Cellular componenti

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 44MitochondrionSequence analysisAdd BLAST44
ChainiPRO_000025544945 – 763Iron-sulfur clusters transporter ATM1, mitochondrialAdd BLAST719

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

STRINGi5270.UM00597P0.

Structurei

3D structure databases

ProteinModelPortaliQ4PH16.
SMRiQ4PH16.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini168 – 463ABC transmembrane type-1PROSITE-ProRule annotationAdd BLAST296
Domaini497 – 733ABC transporterPROSITE-ProRule annotationAdd BLAST237

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni342 – 346Glutathione bindingBy similarity5
Regioni405 – 408Glutathione bindingBy similarity4

Sequence similaritiesi

Keywords - Domaini

Transit peptide, Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoidiQ4PH16.
KOiK05663.
OMAiYEAQRYD.
OrthoDBiEOG092C3H79.

Family and domain databases

InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00664. ABC_membrane. 1 hit.
PF00005. ABC_tran. 1 hit.
SMARTiView protein in SMART
SM00382. AAA. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF90123. SSF90123. 1 hit.
PROSITEiView protein in PROSITE
PS50929. ABC_TM1F. 1 hit.
PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q4PH16-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRVAIRRLPW QATDARHRTI GLVSTNRLPS RIQPRSISST SIAALVYHSR
60 70 80 90 100
NSLRTNIFDI AATPSSRYGS SQRFYQHMAA DRDGDHVPKH QAKMLPGSAS
110 120 130 140 150
DKIIAAASPA SKSASSPAQK KQPDGDDPLN LNSREKTVKE QRLVDWAIIK
160 170 180 190 200
KLIQYVWPKG DFGTKQRVVL ALALLIGGKL LNVQVPFFFK TIVDRLNDVV
210 220 230 240 250
NAPLDMSNPN TVWVVAGSAV LGYGLARVGA AAFSELRNAV FANVAQRSIR
260 270 280 290 300
RVAKSVFTHL LALDLGWHLT RQTGGLTRAI DRGTKGISFL LTSIVFHIVP
310 320 330 340 350
TALEISMVCG ILSYKCGPSF AAVTAITMAA YAWFTIRTTS WRTRFRKEAN
360 370 380 390 400
AADNRAATTS VDSLLNYEAV KYFNNEKHEI AKYDAALADY EKSSIKVATS
410 420 430 440 450
LAALNSGQNA IFSTSLTVMM LLAAQGVTNG TMTVGDLVMV NQLVFQLSLP
460 470 480 490 500
LNFLGTVYRE LRQSLVDMET MFNLENVNVA VKEDKNAPPL KVSGGEIRFE
510 520 530 540 550
NVTFGYHPDR PIFRNISFTV PAGYKTAFVG PSGCGKSTIF RLLFRFYEPQ
560 570 580 590 600
SGKIYIDGQD ITKVSLESLR RHIGVVPQDT PLFNDDIRHN IRYGRLDASD
610 620 630 640 650
EDVEKAARAA KVDQIVLNLP EGYSTKVGER GLMISGGEKQ RLAVARLLLK
660 670 680 690 700
NPSVLFFDEA TSALDSYTET ELMRNIHATL LADKKTAIFV AHRLRTISDS
710 720 730 740 750
DFIIVLQGGG VKEQGTHDQL MDSKGLYWDL WQAQSTVGVG HGAGANEHLQ
760
DLERDQNSST TPM
Length:763
Mass (Da):84,056
Last modified:July 19, 2005 - v1
Checksum:iE0C578C00130D258
GO

Sequence cautioni

The sequence KIS72179 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM003140 Genomic DNA. Translation: KIS72179.1. Different initiation.
RefSeqiXP_011386421.1. XM_011388119.1.

Genome annotation databases

EnsemblFungiiKIS72179; KIS72179; UMAG_00597.
GeneIDi23561854.
KEGGiuma:UMAG_00597.

Similar proteinsi

Entry informationi

Entry nameiATM1_USTMA
AccessioniPrimary (citable) accession number: Q4PH16
Secondary accession number(s): A0A0D1E8N7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: July 19, 2005
Last modified: July 5, 2017
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families