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Protein

Solute carrier family 25 member 38 homolog

Gene

UMAG_10880

Organism
Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Mitochondrial carrier required for the biosynthesis of heme, possibly by facilitating 5-aminolevulinate (ALA) production. May act by importing glycine into mitochondria or by exchanging glycine for ALA across the mitochondrial inner membrane.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransport

Names & Taxonomyi

Protein namesi
Recommended name:
Solute carrier family 25 member 38 homologUniRule annotation
Gene namesi
ORF Names:UMAG_10880
OrganismiUstilago maydis (strain 521 / FGSC 9021) (Corn smut fungus)
Taxonomic identifieri237631 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaUstilaginomycotinaUstilaginomycetesUstilaginalesUstilaginaceaeUstilago
Proteomesi
  • UP000000561 Componentsi: Chromosome 3, Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:UMAG_10880.

Subcellular locationi

  • Mitochondrion inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei41 – 66Helical; Name=1UniRule annotationAdd BLAST26
Transmembranei112 – 138Helical; Name=2UniRule annotationAdd BLAST27
Transmembranei170 – 195Helical; Name=3UniRule annotationAdd BLAST26
Transmembranei226 – 249Helical; Name=4UniRule annotationAdd BLAST24
Transmembranei270 – 296Helical; Name=5UniRule annotationAdd BLAST27
Transmembranei349 – 367Helical; Name=6UniRule annotationAdd BLAST19

GO - Cellular componenti

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004252671 – 399Solute carrier family 25 member 38 homologAdd BLAST399

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati35 – 137Solcar 1Add BLAST103
Repeati164 – 251Solcar 2Add BLAST88
Repeati266 – 374Solcar 3Add BLAST109

Sequence similaritiesi

Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. [View classification]UniRule annotation

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoidiQ4PDL5.
KOiK15118.
OrthoDBiEOG092C3NVU.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
HAMAPiMF_03064. SLC25A38. 1 hit.
InterProiView protein in InterPro
IPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
IPR030847. SLC25A38.
PfamiView protein in Pfam
PF00153. Mito_carr. 3 hits.
PRINTSiPR00926. MITOCARRIER.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiView protein in PROSITE
PS50920. SOLCAR. 2 hits.

Sequencei

Sequence statusi: Complete.

Q4PDL5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATASSSDDA GAAMSISIAN SSKRPIATTK TAASIPPYAT LAFGALSGFA
60 70 80 90 100
SCVLLQPFDL LKTRLQQLDH RPLSPVSNKS ISKPQYASRT QKLVAITKDI
110 120 130 140 150
VHTHGYQGLW RGTAPTVIRN VPGVALYFYS VSHLRSVASQ RQIPLISVAI
160 170 180 190 200
PSDASSNTST LAKLSTTGNL LTGAVARVTV GFILSPVTVV KARFESSNFS
210 220 230 240 250
AATERTLLSS MREIRAQSGF RGFFQGFTAT ALRDAPYAGL YLALYEACKT
260 270 280 290 300
NLAGLSRSMD GGLGTGNWMV VSASGLLAGT LATLLTHPFD IIKTRMQTTP
310 320 330 340 350
ADTLHQIALA HDPKSTLSPS VLRDSLKPSV WGMTKHLWAS SGPRALLDGL
360 370 380 390
GLRCARKAAS SAIGWSIFER GRSWYTEREA SSSAQEAGTG TRLLDHKQV
Length:399
Mass (Da):42,473
Last modified:February 19, 2014 - v2
Checksum:i10741CB2DE8A3AE6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM003142 Genomic DNA. Translation: KIS70633.1.
RefSeqiXP_011388010.1. XM_011389708.1.

Genome annotation databases

EnsemblFungiiKIS70633; KIS70633; UMAG_10880.
GeneIDi23566850.
KEGGiuma:UMAG_10880.

Similar proteinsi

Entry informationi

Entry nameiS2538_USTMA
AccessioniPrimary (citable) accession number: Q4PDL5
Secondary accession number(s): A0A0D1CW78
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 19, 2014
Last sequence update: February 19, 2014
Last modified: March 15, 2017
This is version 73 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families