Reviewed, UniProtKB/Swiss-Prot Q4PD66 (CCPR2_USTMA)

Names and origin

Protein names

Recommended name:
    Putative heme-binding peroxidase
    EC=1.11.1.-

Gene names

Name:	CCP2
ORF Names:	UM01947

Organism

Ustilago maydis (Smut fungus) [Complete proteome]

Taxonomic identifier

5270 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Basidiomycota › Ustilaginomycotina › Ustilaginomycetes › Ustilaginales › Ustilaginaceae › Ustilago

Protein attributes

Sequence length	330 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Destroys radicals which are normally produced within the cells and which are toxic to biological systems By similarity.
Cofactor	Binds 1 heme B (iron-protoporphyrin IX) group per subunit By similarity.
Sequence similarities	Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.

Ontologies

Keywords
Ligand	Heme Iron Metal-binding
Molecular function	Oxidoreductase Peroxidase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW response to oxidative stress Inferred from electronic annotation. Source: InterPro
Molecular function	heme binding Inferred from electronic annotation. Source: InterPro peroxidase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 330	330	Putative heme-binding peroxidase		PRO_0000055589
Sites
	Active site	38	1	Proton acceptor By similarity
	Active site	178	1	Tryptophan radical intermediate By similarity
	Metal binding	162	1	Iron (heme axial ligand) By similarity
	Site	34	1	Transition state stabilizer By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q4PD66-1 [UniParc]. Last modified July 19, 2005. Version 1. Checksum: D8D51F57FD2F4ABF	FASTA	330	36,483
	10 20 30 40 50 60 MSKLGDYAAV KKDILAVLKQ PEYDDGSAGP VLVRLAWHAS GTYCARTDTG GSNGAGMRYE 70 80 90 100 110 120 AEGGDPANAG LQHARVFLEP IKEKHSWITY ADLWTLAGVV AIEAMGGPSI QWKPGRTDFA 130 140 150 160 170 180 DDSRLPPRGR LPDGAQGADH LRFIFNRMGF NDQEIVALSG AHNLGRCHSD RSGFEGPWVN 190 200 210 220 230 240 SPTRFSNQYY KLLLKLKWQP KKWDGPFQYV AKAPGADDDD EQLMMLPTDY ALIQDEKMRP 250 260 270 280 290 300 WVEKYAEDRD AFFNDFAKVF AKLIELGVYR DESGIARADK MKQFKGEYKS APQKSPVPGA 310 320 330 PGAGKDGEAN PLARQNERAH GQAQHALAKL

References

[1]

"Insights from the genome of the biotrophic fungal plant pathogen Ustilago maydis." Kaemper J., Kahmann R., Boelker M., Ma L.-J., Brefort T., Saville B.J., Banuett F., Kronstad J.W., Gold S.E., Mueller O., Perlin M.H., Woesten H.A.B., de Vries R., Ruiz-Herrera J., Reynaga-Pena C.G., Snetselaar K., McCann M., Perez-Martin J. , Feldbruegge M., Basse C.W., Steinberg G., Ibeas J.I., Holloman W., Guzman P., Farman M.L., Stajich J.E., Sentandreu R., Gonzalez-Prieto J.M., Kennell J.C., Molina L., Schirawski J., Mendoza-Mendoza A., Greilinger D., Muench K., Roessel N., Scherer M., Vranes M., Ladendorf O., Vincon V., Fuchs U., Sandrock B., Meng S., Ho E.C.H., Cahill M.J., Boyce K.J., Klose J., Klosterman S.J., Deelstra H.J., Ortiz-Castellanos L., Li W., Sanchez-Alonso P., Schreier P.H., Haeuser-Hahn I., Vaupel M., Koopmann E., Friedrich G., Voss H., Schlueter T., Margolis J., Platt D., Swimmer C., Gnirke A., Chen F., Vysotskaia V., Mannhaupt G., Gueldener U., Muensterkoetter M., Haase D., Oesterheld M., Mewes H.-W., Mauceli E.W., DeCaprio D., Wade C.M., Butler J., Young S.K., Jaffe D.B., Calvo S.E., Nusbaum C., Galagan J.E., Birren B.W. Nature 444:97-101(2006) [PubMed: 17080091] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 521.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AACP01000071 Genomic DNA. Translation: EAK82401.1.
RefSeq	XP_758094.1.
3D structure databases
ModBase	Search...
Protein family/group databases
PeroxiBase	2356. UmCcP01.
Genome annotation databases
GeneID	3630012.
KEGG	uma:UM01947.1.
Phylogenomic databases
OMA	Q4PD66. PTRFSNQ.
Family and domain databases
InterPro	IPR002207. Asc_perxdse. IPR002016. Haem_peroxidase_pln/fun/bac. IPR019794. Peroxidases_AS. IPR019793. Peroxidases_heam-ligand_BS. [Graphical view]
Pfam	PF00141. peroxidase. 1 hit. [Graphical view]
PRINTS	PR00459. ASPEROXIDASE. PR00458. PEROXIDASE.
PROSITE	PS00435. PEROXIDASE_1. False negative. PS00436. PEROXIDASE_2. 1 hit. PS50873. PEROXIDASE_4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CCPR2_USTMA

Accession

Primary (citable) accession number: Q4PD66

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 20, 2005
Last sequence update:	July 19, 2005
Last modified:	June 16, 2009
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)