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Protein

Serine/threonine-protein phosphatase 2A activator 2

Gene

RRD2

Organism
Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg2+ by dissociating the inactive form from the complex (By similarity).By similarity

Catalytic activityi

Peptidylproline (omega=180) = peptidylproline (omega=0).

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase, Rotamase

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphatase 2A activator 2 (EC:5.2.1.8)
Alternative name(s):
Peptidyl-prolyl cis-trans isomerase PTPA-2
Short name:
PPIase PTPA-2
Short name:
Rotamase PTPA-2
Phosphotyrosyl phosphatase activator 2
Gene namesi
Name:RRD2
ORF Names:UMAG_02103
OrganismiUstilago maydis (strain 521 / FGSC 9021) (Corn smut fungus)
Taxonomic identifieri237631 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaUstilaginomycotinaUstilaginomycetesUstilaginalesUstilaginaceaeUstilago
Proteomesi
  • UP000000561 Componentsi: Chromosome 5, Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 457457Serine/threonine-protein phosphatase 2A activator 2PRO_0000226118Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ4PCR0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PTPA-type PPIase family.Curated

Phylogenomic databases

HOGENOMiHOG000205736.
InParanoidiQ4PCR0.
KOiK17605.
OMAiYMYLGCI.
OrthoDBiEOG092C3CMG.

Family and domain databases

InterProiIPR004327. Phstyr_phstse_ac.
[Graphical view]
PANTHERiPTHR10012. PTHR10012. 1 hit.
PfamiPF03095. PTPA. 1 hit.
[Graphical view]
PIRSFiPIRSF016325. Phstyr_phstse_ac. 1 hit.

Sequencei

Sequence statusi: Complete.

Q4PCR0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPPAALQATV SESVKDAIIS KLRQPPSAVP SREWSAETRT SLTPADAGIA
60 70 80 90 100
EARASAEDIE LVDLQHHNFS EPRKRIVSPA SLSRFEHSQA FAEILAFICV
110 120 130 140 150
CNTRVVGKTL TEEIQISSAC RTILEMLDQV AALRESTPPD ASIGSSRFGN
160 170 180 190 200
PAFRTFYAKI RENTDRLHRM IPGLETDSEW SRAARAELSV YFQECWGNEK
210 220 230 240 250
RIDYGSGMEL NMACWLLCLC KLRILRLPED GACIVLRIFW TYVQVMRDIQ
260 270 280 290 300
SSYWLEPAGS HGVWGLDDYH FLPFLWGAGQ LSSHRHLRPK AIHDAEIVDE
310 320 330 340 350
FAPKYMYLAC IQFINSVKTA SLRWHSPMLD DISGAKSWSK VNQGMIKMYR
360 370 380 390 400
AEVLKKLPIA QHIFFGSLLR FPEPATGELE EEDVEEDAHG HIHPAGKPHA
410 420 430 440 450
HGTGEGQAAG WGDCCGIPIP SAFAAAEQEK KRQQGNFSST MLGEKPFGTG

VRRIPFD
Length:457
Mass (Da):51,009
Last modified:July 19, 2005 - v1
Checksum:i91D8CD064DD173AD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM003144 Genomic DNA. Translation: KIS69567.1.
RefSeqiXP_011388468.1. XM_011390166.1.

Genome annotation databases

EnsemblFungiiUM02103T0; UM02103P0; UM02103.
GeneIDi23562927.
KEGGiuma:UMAG_02103.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM003144 Genomic DNA. Translation: KIS69567.1.
RefSeqiXP_011388468.1. XM_011390166.1.

3D structure databases

ProteinModelPortaliQ4PCR0.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiUM02103T0; UM02103P0; UM02103.
GeneIDi23562927.
KEGGiuma:UMAG_02103.

Phylogenomic databases

HOGENOMiHOG000205736.
InParanoidiQ4PCR0.
KOiK17605.
OMAiYMYLGCI.
OrthoDBiEOG092C3CMG.

Family and domain databases

InterProiIPR004327. Phstyr_phstse_ac.
[Graphical view]
PANTHERiPTHR10012. PTHR10012. 1 hit.
PfamiPF03095. PTPA. 1 hit.
[Graphical view]
PIRSFiPIRSF016325. Phstyr_phstse_ac. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiPTPA2_USTMA
AccessioniPrimary (citable) accession number: Q4PCR0
Secondary accession number(s): A0A0D1C800
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 7, 2006
Last sequence update: July 19, 2005
Last modified: September 7, 2016
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.