Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q4PBD6 (Q4PBD6_USTMA) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
6-phosphogluconate dehydrogenase, decarboxylating PIRNR PIRNR000109 RuleBase RU000485
EC=1.1.1.44 PIRNR PIRNR000109 RuleBase RU000485
Gene names
ORF Names:UM02577.1 EMBL EAK83747.1
OrganismUstilago maydis (strain 521 / FGSC 9021) (Smut fungus)
Taxonomic identifier237631 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Basidiomycota › Ustilaginomycotina › Ustilaginomycetes › Ustilaginales › Ustilaginaceae › Ustilago

Protein attributes

Sequence length492 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO2, with concomitant reduction of NADP to NADPH By similarity. PIRNR PIRNR000109

Catalytic activity

6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH. PIRNR PIRNR000109 RuleBase RU000485

Pathway

Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 3/3. PIRNR PIRNR000109 RuleBase RU004281

Subunit structure

Homodimer By similarity. PIRNR PIRNR000109

Sequence similarities

Belongs to the 6-phosphogluconate dehydrogenase family. PIRNR PIRNR000109 RuleBase RU000485

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding13 – 186NADP By similarity PIRSR PIRSR000109-3
Nucleotide binding36 – 383NADP By similarity PIRSR PIRSR000109-3
Nucleotide binding78 – 803NADP By similarity PIRSR PIRSR000109-3
Region132 – 1343Substrate binding By similarity PIRSR PIRSR000109-2
Region189 – 1902Substrate binding By similarity PIRSR PIRSR000109-2

Sites

Active site1861Proton acceptor By similarity PIRSR PIRSR000109-1
Active site1931Proton donor By similarity PIRSR PIRSR000109-1
Binding site1061NADP By similarity PIRSR PIRSR000109-3
Binding site1061Substrate By similarity PIRSR PIRSR000109-2
Binding site1941Substrate By similarity PIRSR PIRSR000109-2
Binding site2631Substrate; via amide nitrogen By similarity PIRSR PIRSR000109-2
Binding site2901Substrate By similarity PIRSR PIRSR000109-2
Binding site4491Substrate; shared with dimeric partner By similarity PIRSR PIRSR000109-2
Binding site4551Substrate; shared with dimeric partner By similarity PIRSR PIRSR000109-2

Sequences

Sequence LengthMass (Da)Tools
Q4PBD6 [UniParc].

Last modified July 19, 2005. Version 1.
Checksum: ED7ACA41267FA168

FASTA49253,947
        10         20         30         40         50         60 
MSSQAVADIG LIGLAVMGQN LILNMNDKGF TVCAYNRTTS KVDDFLANEA KGTNVVGAKS 

        70         80         90        100        110        120 
IEEFVAKLKR PRKMILLVKA GPAVDAFIEQ LLPHLEQGDI VIDGGNSHYP DSIRRCKELE 

       130        140        150        160        170        180 
AKGILFVGSG VSGGEEGARH GPSLMPGGSD AAWPHIKEIF QKTAAQSDGE PCCDWVGQTG 

       190        200        210        220        230        240 
AGHYVKMVHN GIEYGDMQLI CEAYDILKHG LGLKEGEIGD IFTKWNTGVL DSFLIEITRD 

       250        260        270        280        290        300 
ILKYNDEDGA PLLTKIMDSA GQKGTGKWTA INALDLGQPV TLIGEAVFAR CLSSLKGERT 

       310        320        330        340        350        360 
RASKILGGPQ IKPFEGNKEQ FIADLEQALY ASKIVSYAQG FMLMREAAKE YDWKLNNPSI 

       370        380        390        400        410        420 
ALMWRGGCII RSVFLKDITA AFRKNPELEN LLFDDFFNKA IHNAQEGWRR VVAQAILWGI 

       430        440        450        460        470        480 
PTPAFSTALA FFDGYRRELL PANLLQAQRD YFGAHTFRVL PQFASEKLPE GQDIHINWTG 

       490 
RGGNVSASTY QA

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AACP01000086 Genomic DNA. Translation: EAK83747.1.
RefSeqXP_758724.1. XM_753631.1.

3D structure databases

ProteinModelPortalQ4PBD6.
SMRQ4PBD6. Positions 7-479.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ4PBD6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiUM02577T0; UM02577P0; UM02577.
GeneID3630658.
KEGGuma:UM02577.1.

Phylogenomic databases

eggNOGfuNOG05795.
HOGENOMHBG286913.
OMAITKAYRE.
OrthoDBEOG4VDT6Z.

Family and domain databases

InterProIPR008927. 6-PGluconate_DH_C-like.
IPR006114. 6PGDH_C.
IPR006113. 6PGDH_decarbox.
IPR006115. 6PGDH_NADP-bd.
IPR006184. 6PGdom_BS.
IPR013328. DH_multihelical.
IPR012284. Fibritin/6PGD_C-extension.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:1.20.5.320. Fibritin/6PGD_C-extension. 1 hit.
G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
G3DSA:1.10.1040.10. Opine_DH. 1 hit.
KOK00033.
PfamPF00393. 6PGD. 1 hit.
PF03446. NAD_binding_2. 1 hit.
[Graphical view]
PIRSFPIRSF000109. 6PGD. 1 hit.
SUPFAMSSF48179. 6DGDH_C_like. 1 hit.
TIGRFAMsTIGR00873. Gnd. 1 hit.
PROSITEPS00461. 6PGD. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ4PBD6_USTMA
AccessionPrimary (citable) accession number: Q4PBD6
Entry history
Integrated into UniProtKB/TrEMBL: July 19, 2005
Last sequence update: July 19, 2005
Last modified: December 14, 2011
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info