Q4P958 (TMEDA_USTMA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Endoplasmic reticulum vesicle protein 25

Gene names

Name:	ERV25
ORF Names:	UM03355

Organism

Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus) [Reference proteome]

Taxonomic identifier

237631 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Basidiomycota › Ustilaginomycotina › Ustilaginomycetes › Ustilaginales › Ustilaginaceae › Ustilago › Ustilago maydis

Protein attributes

Sequence length	224 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Constituent of COPII-coated endoplasmic reticulum-derived transport vesicles. Required for efficient transport of a subset of secretory proteins to the Golgi. Facilitates retrograde transport from the Golgi to the endoplasmic reticulum By similarity.
Subcellular location	Endoplasmic reticulum membrane; Single-pass type I membrane protein By similarity. Golgi apparatus membrane; Single-pass type I membrane protein By similarity. Note: Recycles between endoplasmic reticulum and Golgi By similarity.
Sequence similarities	Belongs to the EMP24/GP25L family. Contains 1 GOLD domain.

Ontologies

Keywords
Biological process	ER-Golgi transport Protein transport Transport
Cellular component	Endoplasmic reticulum Golgi apparatus Membrane
Domain	Signal Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	protein transport Inferred from electronic annotation. Source: UniProtKB-KW vesicle-mediated transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	Golgi membrane Inferred from electronic annotation. Source: UniProtKB-SubCell endoplasmic reticulum membrane Inferred from electronic annotation. Source: UniProtKB-SubCell integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 25	25	Potential
	Chain	26 – 224	199	Endoplasmic reticulum vesicle protein 25		PRO_0000237698
Regions
	Topological domain	26 – 190	165	Lumenal Potential
	Transmembrane	191 – 211	21	Helical; Potential
	Topological domain	212 – 224	13	Cytoplasmic Potential
	Domain	38 – 131	94	GOLD

Sequences

	Sequence		Length	Mass (Da)
	Q4P958 [UniParc]. Last modified July 19, 2005. Version 1. Checksum: 540216754977A8E4	FASTA	224	24,828
	10 20 30 40 50 60 MIPPRSLGST AALLLVLLFT TLASAIKFDL PSNAHPHTKC IWNYALSDSL VIVTASVVAK 70 80 90 100 110 120 EPFDFSHQRV DIEVVDGSQH NNVYLSKKAI KGETRLAINT HSHADLGVCF KNTLTSKSGN 130 140 150 160 170 180 QIPVVTIDLD VDIGADAVDY NAIANQESLS GLETEMRKLE AVANEIVNEM EYLKKRELRM 190 200 210 220 ADTNLSTNMR VTNFAILTLI ALIALGVWQV FHLRGFFKRK YLID

References

[1]

"Insights from the genome of the biotrophic fungal plant pathogen Ustilago maydis." Kaemper J., Kahmann R., Boelker M., Ma L.-J., Brefort T., Saville B.J., Banuett F., Kronstad J.W., Gold S.E., Mueller O., Perlin M.H., Woesten H.A.B., de Vries R., Ruiz-Herrera J., Reynaga-Pena C.G., Snetselaar K., McCann M., Perez-Martin J. , Feldbruegge M., Basse C.W., Steinberg G., Ibeas J.I., Holloman W., Guzman P., Farman M.L., Stajich J.E., Sentandreu R., Gonzalez-Prieto J.M., Kennell J.C., Molina L., Schirawski J., Mendoza-Mendoza A., Greilinger D., Muench K., Roessel N., Scherer M., Vranes M., Ladendorf O., Vincon V., Fuchs U., Sandrock B., Meng S., Ho E.C.H., Cahill M.J., Boyce K.J., Klose J., Klosterman S.J., Deelstra H.J., Ortiz-Castellanos L., Li W., Sanchez-Alonso P., Schreier P.H., Haeuser-Hahn I., Vaupel M., Koopmann E., Friedrich G., Voss H., Schlueter T., Margolis J., Platt D., Swimmer C., Gnirke A., Chen F., Vysotskaia V., Mannhaupt G., Gueldener U., Muensterkoetter M., Haase D., Oesterheld M., Mewes H.-W., Mauceli E.W., DeCaprio D., Wade C.M., Butler J., Young S.K., Jaffe D.B., Calvo S.E., Nusbaum C., Galagan J.E., Birren B.W. Nature 444:97-101(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 521 / FGSC 9021.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AACP01000114 Genomic DNA. Translation: EAK84223.1.
RefSeq	XP_759502.1. XM_754409.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	5270.UM03355.1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	UM03355T0; UM03355P0; UM03355.
GeneID	3631444.
KEGG	uma:UM03355.1.
Phylogenomic databases
eggNOG	NOG323830.
HOGENOM	HOG000160227.
OMA	DYNAIAN.
OrthoDB	EOG47H90K.
Family and domain databases
InterPro	IPR009038. GOLD. [Graphical view]
Pfam	PF01105. EMP24_GP25L. 1 hit. [Graphical view]
PROSITE	PS50866. GOLD. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TMEDA_USTMA

Accession

Primary (citable) accession number: Q4P958

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2006
Last sequence update:	July 19, 2005
Last modified:	April 3, 2013
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program