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Protein

Helicase SWR1

Gene

SWR1

Organism
Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.By similarity

Catalytic activityi

ATP + H2O = ADP + phosphate.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi1015 – 1022ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivator, Chromatin regulator, DNA-binding, Helicase, Hydrolase
Biological processTranscription, Transcription regulation
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Helicase SWR1 (EC:3.6.4.12)
Gene namesi
Name:SWR1
ORF Names:UMAG_05485
OrganismiUstilago maydis (strain 521 / FGSC 9021) (Corn smut fungus)
Taxonomic identifieri237631 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaUstilaginomycotinaUstilaginomycetesUstilaginalesUstilaginaceaeUstilago
Proteomesi
  • UP000000561 Componentsi: Chromosome 18, Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:UMAG_05485.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000743731 – 1830Helicase SWR1Add BLAST1830

Interactioni

Subunit structurei

Component of the SWR1 chromatin-remodeling complex.By similarity

Protein-protein interaction databases

STRINGi5270.UM05485P0.

Structurei

3D structure databases

ProteinModelPortaliQ4P328.
SMRiQ4P328.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini556 – 628HSAPROSITE-ProRule annotationAdd BLAST73
Domaini1002 – 1167Helicase ATP-bindingPROSITE-ProRule annotationAdd BLAST166
Domaini1537 – 1692Helicase C-terminalPROSITE-ProRule annotationAdd BLAST156

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili602 – 679Sequence analysisAdd BLAST78

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi1118 – 1121DEAH box4

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi687 – 719Asp-richAdd BLAST33

Sequence similaritiesi

Keywords - Domaini

Coiled coil

Phylogenomic databases

InParanoidiQ4P328.
KOiK11681.
OMAiYFLMPSS.
OrthoDBiEOG092C1YH4.

Family and domain databases

CDDicd00079. HELICc. 1 hit.
InterProiView protein in InterPro
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR014012. HSA_dom.
IPR027417. P-loop_NTPase.
IPR000330. SNF2_N.
PfamiView protein in Pfam
PF00271. Helicase_C. 1 hit.
PF07529. HSA. 1 hit.
PF00176. SNF2_N. 1 hit.
SMARTiView protein in SMART
SM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
SM00573. HSA. 1 hit.
SUPFAMiSSF52540. SSF52540. 3 hits.
PROSITEiView protein in PROSITE
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS51204. HSA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q4P328-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSPGDSALDY AKRQAGNVSS QAPSRPSSEN DANGTVSTSN EHPSNEAGPS
60 70 80 90 100
RPRSMGSERS ASPQQGTTPK VPTKRRRLNA ELAFSSPGPA FQVEQHGSEA
110 120 130 140 150
QSDSNDSSGR ARRPRRSTTL TKSGSNESQD RRSSAHIPKR KEEAGESRNL
160 170 180 190 200
AESVPKNKLK LNNGKARASD EVELRESSLS LVLPSRSRSR SKSVVKLEPD
210 220 230 240 250
QDSAFPQEVA TPTLQPTRPK PQITPLTALN PQAALSEILA RRRSERIALA
260 270 280 290 300
QSDLEDVHDG HDMLVRELFH LTKFVTMVGY DPDVARTDQS DVFTTFKHAH
310 320 330 340 350
DLRFSLDDSG SGAEASTAAR VTRRRVNARL ESLSLKRPDP PSTPSTPSFS
360 370 380 390 400
KVKVDDDKKS APEGRRNRRF SSVTGAQPRV NGAHTLETGH SDDTDDSSEE
410 420 430 440 450
EDSEGSDLDA YSPDGREKGD AKDYNASRKG DAKRARLSST PHKRHRAKVQ
460 470 480 490 500
DASSNAPVKR TGPRKSKALD ELDAFILRQQ PRPLPDHPPP LHILAPHQIP
510 520 530 540 550
AHRRFGGDLD ALYESFNMLQ DDEGGLEDDD LETYIKLDQR WRAGLPIHPE
560 570 580 590 600
AGSTTRHAVQ KVPRNKSHHD HLLESVTSSY SQMRQYAKLK QQNSRKVARM
610 620 630 640 650
IAQHWERQLG TSEREKKAEE RRLRALAKWT LREVLKQWRL AVNVVRARKA
660 670 680 690 700
AAEKAEKEKS DKEQLNAILE QSTAMLKKQH EVMTRADSLD DSDDEGSDRT
710 720 730 740 750
NYGSDGSAES EISDIDDDDN QLIQIQDELP SVSPEQSLDM LTPVPEEADG
760 770 780 790 800
SKDRVSNTTD HEAATANGDP TVVVESESQP SRRPQRRTAR TKTFKARDSK
810 820 830 840 850
LDADDIEFND AGNDDEQEDA ELERQMLEED EEDDSEDAGL AADANIPIEE
860 870 880 890 900
LLKRYGYGQE ADQDAEDSDA GEDAVSNDDS LENSATKDGS EDVAAVASIK
910 920 930 940 950
IQEDAEVEEE RPVQEDSMPD EAMDLEDDAV STALNRPSDA LLVDDHSDAE
960 970 980 990 1000
SAATSGRRSS RRSMTRASSI VSSDRHATRL RQPFLLRGQL RPYQQIGFEW
1010 1020 1030 1040 1050
LCSLYANGVN GILADEMGLG KTIQTISLLA HLACDKGVWG PHLVVAPTSV
1060 1070 1080 1090 1100
MLNWEVEFKK FLPGFKILSY YGNQKERKEK RIGWNTENSF NVCITSYQLV
1110 1120 1130 1140 1150
LADQHIFRRK PWVYLVLDEA HHIKNFRSQR WQTLLGFNSQ RRLLLTGTPL
1160 1170 1180 1190 1200
QNNLMDLWSL MYFLMPNGAT ELPGGGAFAN MKDFQDWFSN PLDKAIEGGT
1210 1220 1230 1240 1250
SMNDETRAMV QKLHAVLRPY LLRRLKSEVE KELPSKYEHV ITCRLSKRQR
1260 1270 1280 1290 1300
FLYNDFMSRA KTRESLASGN YLSIINCLMQ LRKVCNHPDL FEVRPIVTSF
1310 1320 1330 1340 1350
AMSRSVVADY EIKDLLVRRR LLQENVWEKV DLDVTNLRIT DGEEHLTAIE
1360 1370 1380 1390 1400
SRDLRRLNAA KKLPHFREAV PEPRELDTWT LEGFERSREQ RKLVDRMEKW
1410 1420 1430 1440 1450
KHMAYLNQYR CTKRPIYGSG LIKMLTEAGE AARLEPLEQH ESDRRGFLTR
1460 1470 1480 1490 1500
CDSVLRIVQS RSTRRENMQA LIDRFAFVTP RAVAVDMPRW ALPGLEAHQR
1510 1520 1530 1540 1550
PDMVKREFDT VHPVAVKLHI AFPDASLLQY DCGKLQQLDI LMRRLKEGGH
1560 1570 1580 1590 1600
RILIFTQMTR VLDILESFLN YHGYRYLRLD GATKVESRQA LTEQFNRDAR
1610 1620 1630 1640 1650
ISAFILSTRS GGLGINLTGA DTVLFYDLDW NAAIEAQCMD RAHRIGQTRD
1660 1670 1680 1690 1700
VHIYRFVTEH TIEENMLRKA NQKRLLDNVV IQQGEFNTET LAKRLDWTDM
1710 1720 1730 1740 1750
LDESGKIGDV EVVVADQGVG ARDVESAFLQ AEDDEDRQAA LRARHEMFID
1760 1770 1780 1790 1800
DADFEEHQPS TSRPNTASAT PLAHTASDGA RPDNGAHAAD ALDAHEIENE
1810 1820 1830
HQEQEQEQEQ AASIDDYMLA FVESDWPFFA
Length:1,830
Mass (Da):206,325
Last modified:July 19, 2005 - v1
Checksum:i2FECC06A81803356
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM003157 Genomic DNA. Translation: KIS66492.1.
RefSeqiXP_011391816.1. XM_011393514.1.

Genome annotation databases

EnsemblFungiiKIS66492; KIS66492; UMAG_05485.
GeneIDi23565365.
KEGGiuma:UMAG_05485.

Similar proteinsi

Entry informationi

Entry nameiSWR1_USTMA
AccessioniPrimary (citable) accession number: Q4P328
Secondary accession number(s): A0A0D1BX16
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: July 19, 2005
Last modified: October 25, 2017
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families