Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q4N698

- Q4N698_THEPA

UniProt

Q4N698 - Q4N698_THEPA

Protein

Histone deacetylase

Gene

TP02_0039

Organism
Theileria parva (East coast fever infection agent)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 49 (01 Oct 2014)
      Sequence version 1 (02 Aug 2005)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone.UniRule annotation

    GO - Molecular functioni

    1. NAD-dependent histone deacetylase activity (H3-K14 specific) Source: UniProtKB-EC
    2. NAD-dependent histone deacetylase activity (H3-K18 specific) Source: UniProtKB-EC
    3. NAD-dependent histone deacetylase activity (H3-K9 specific) Source: UniProtKB-EC
    4. NAD-dependent histone deacetylase activity (H4-K16 specific) Source: UniProtKB-EC

    GO - Biological processi

    1. regulation of transcription, DNA-templated Source: UniProtKB-KW
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Chromatin regulatorUniRule annotation, HydrolaseUniRule annotationSAAS annotation

    Keywords - Biological processi

    Transcription, Transcription regulationUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Histone deacetylaseUniRule annotation (EC:3.5.1.98UniRule annotation)
    Gene namesi
    Ordered Locus Names:TP02_0039Imported
    OrganismiTheileria parva (East coast fever infection agent)Imported
    Taxonomic identifieri5875 [NCBI]
    Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaPiroplasmidaTheileriidaeTheileria
    ProteomesiUP000001949: Unassembled WGS sequence

    Organism-specific databases

    EuPathDBiPiroplasmaDB:TP02_0039.

    Subcellular locationi

    Nucleus UniRule annotation

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    NucleusUniRule annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi5875.TP02_0039.

    Structurei

    3D structure databases

    ProteinModelPortaliQ4N698.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the histone deacetylase family. HD Type 1 subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0123.
    HOGENOMiHOG000225180.
    KOiK06067.

    Family and domain databases

    Gene3Di3.40.800.20. 1 hit.
    InterProiIPR000286. His_deacetylse.
    IPR003084. His_deacetylse_1.
    IPR023801. His_deacetylse_dom.
    [Graphical view]
    PANTHERiPTHR10625. PTHR10625. 1 hit.
    PfamiPF00850. Hist_deacetyl. 1 hit.
    [Graphical view]
    PIRSFiPIRSF037913. His_deacetylse_1. 1 hit.
    PRINTSiPR01270. HDASUPER.
    PR01271. HISDACETLASE.

    Sequencei

    Sequence statusi: Complete.

    Q4N698-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDKRVSYFYD PDVGSFYYGP GHPMKPQRIR MAHALVLSYD LYRHMEIFRP    50
    HKAVEPELLS FHDSEYVHFL SGVSPENYRD FTYQLKRFNV GEATDCPVFD 100
    GLYVFQQSCS GASIDAAHRL NNQQADICVN WSGGLHHAKR SEASGFCYLN 150
    DIVLGILELL KYHARVMYID IDVHHGDGVE EAFYVTHRVM TISFHKFGNF 200
    FPGTGDVTDV GVSSGKYYSV NVPLNDGIDD ESFVDLFKVV VGKCVEVYCP 250
    GAIVLQCGAD SLTGDRLGRF NLTIKGHAAC VQYVRSLNIP LLVLGGGGYT 300
    IRNVARCWAY ETGVILNKHT DMSNQISLND YYDYYAPDFQ LHLTPSQMTN 350
    YNTKEHLDKI KVKILDNLRY VEKSPGVQFA HVPPDFLTRD DDVDDDLQKQ 400
    VFDEGGGRTS LSTRKRISLI TSSHKLRRRD YKGELYDLPD RDDQIPI 447
    Length:447
    Mass (Da):50,781
    Last modified:August 2, 2005 - v1
    Checksum:i3C88C204C274BDB7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAGK01000002 Genomic DNA. Translation: EAN32325.1.
    RefSeqiXP_764608.1. XM_759515.1.

    Genome annotation databases

    GeneIDi3501619.
    KEGGitpv:TP02_0039.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAGK01000002 Genomic DNA. Translation: EAN32325.1 .
    RefSeqi XP_764608.1. XM_759515.1.

    3D structure databases

    ProteinModelPortali Q4N698.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 5875.TP02_0039.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 3501619.
    KEGGi tpv:TP02_0039.

    Organism-specific databases

    EuPathDBi PiroplasmaDB:TP02_0039.

    Phylogenomic databases

    eggNOGi COG0123.
    HOGENOMi HOG000225180.
    KOi K06067.

    Family and domain databases

    Gene3Di 3.40.800.20. 1 hit.
    InterProi IPR000286. His_deacetylse.
    IPR003084. His_deacetylse_1.
    IPR023801. His_deacetylse_dom.
    [Graphical view ]
    PANTHERi PTHR10625. PTHR10625. 1 hit.
    Pfami PF00850. Hist_deacetyl. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF037913. His_deacetylse_1. 1 hit.
    PRINTSi PR01270. HDASUPER.
    PR01271. HISDACETLASE.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: MugugaImported.

    Entry informationi

    Entry nameiQ4N698_THEPA
    AccessioniPrimary (citable) accession number: Q4N698
    Entry historyi
    Integrated into UniProtKB/TrEMBL: August 2, 2005
    Last sequence update: August 2, 2005
    Last modified: October 1, 2014
    This is version 49 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3