Q4N594 (CYC_THEPA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytochrome c

Gene names

Ordered Locus Names:

TP02_0396

Organism

Theileria parva (East coast fever infection agent) [Reference proteome]

Taxonomic identifier

5875 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Alveolata › Apicomplexa › Aconoidasida › Piroplasmida › Theileriidae › Theileria

Protein attributes

Sequence length	115 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain By similarity.
Subcellular location	Mitochondrion intermembrane space By similarity. Note: Loosely associated with the inner membrane By similarity.
Post-translational modification	Binds 1 heme group per subunit By similarity.
Sequence similarities	Belongs to the cytochrome c family.

Ontologies

Keywords
Biological process	Electron transport Respiratory chain Transport
Cellular component	Mitochondrion
Ligand	Heme Iron Metal-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	mitochondrial intermembrane space Inferred from electronic annotation. Source: UniProtKB-SubCell respiratory chain Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	electron carrier activity Inferred from electronic annotation. Source: InterPro heme binding Inferred from electronic annotation. Source: InterPro iron ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 115	115	Cytochrome c		PRO_0000273193
Sites
	Metal binding	30	1	Iron (heme axial ligand) By similarity
	Metal binding	91	1	Iron (heme axial ligand) By similarity
	Binding site	26	1	Heme (covalent) By similarity
	Binding site	29	1	Heme (covalent) By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q4N594 [UniParc]. Last modified August 2, 2005. Version 1. Checksum: D3E65A6FEB5448C0	FASTA	115	12,579
	10 20 30 40 50 60 MAKPEPDVVI PEGDSSKGAK LFKSKCAQCH TINKGGSVKQ GPNLYGFYGR KSGASDYAYS 70 80 90 100 110 DANKNSGIVW SDKHLFVYLV NPKQYIPGTK MVFAGLKKEQ DRADLIAYLK EASSK

References

[1]

"Genome sequence of Theileria parva, a bovine pathogen that transforms lymphocytes." Gardner M.J., Bishop R., Shah T., de Villiers E.P., Carlton J.M., Hall N., Ren Q., Paulsen I.T., Pain A., Berriman M., Wilson R.J.M., Sato S., Ralph S.A., Mann D.J., Xiong Z., Shallom S.J., Weidman J., Jiang L. , Lynn J., Weaver B., Shoaibi A., Domingo A.R., Wasawo D., Crabtree J., Wortman J.R., Haas B., Angiuoli S.V., Creasy T.H., Lu C., Suh B., Silva J.C., Utterback T.R., Feldblyum T.V., Pertea M., Allen J., Nierman W.C., Taracha E.L.N., Salzberg S.L., White O.R., Fitzhugh H.A., Morzaria S., Venter J.C., Fraser C.M., Nene V. Science 309:134-137(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Muguga.

Web resources

Protein Spotlight

Life shuttle - Issue 76 of November 2006

Cross-references

Sequence databases
EMBL GenBank DDBJ	AAGK01000002 Genomic DNA. Translation: EAN32679.1.
RefSeq	XP_764962.1. XM_759869.1.
3D structure databases
ProteinModelPortal	Q4N594.
SMR	Q4N594. Positions 11-114.
ModBase	Search...
Protein-protein interaction databases
STRING	5875.TP02_0396.
Proteomic databases
PRIDE	Q4N594.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3502047.
KEGG	tpv:TP02_0396.
Organism-specific databases
EuPathDB	PiroplasmaDB:TP02_0396.
Phylogenomic databases
eggNOG	COG3474.
HOGENOM	HOG000009762.
KO	K08738.
ProtClustDB	PTZ00048.
Family and domain databases
InterPro	IPR002327. Cyt_c_1A/1B. IPR009056. Cyt_c_dom. IPR003088. Cyt_c_I. [Graphical view]
PANTHER	PTHR11961. PTHR11961. 1 hit.
Pfam	PF00034. Cytochrom_C. 1 hit. [Graphical view]
PRINTS	PR00604. CYTCHRMECIAB.
SUPFAM	SSF46626. Cytochrome_c. 1 hit.
PROSITE	PS51007. CYTC. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CYC_THEPA

Accession

Primary (citable) accession number: Q4N594

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 23, 2007
Last sequence update:	August 2, 2005
Last modified:	May 29, 2013
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)