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Q4N594

- CYC_THEPA

UniProt

Q4N594 - CYC_THEPA

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Protein

Cytochrome c

Gene

TP02_0396

Organism
Theileria parva (East coast fever infection agent)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity).By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei26 – 261Heme (covalent)PROSITE-ProRule annotation
Binding sitei29 – 291Heme (covalent)PROSITE-ProRule annotation
Metal bindingi30 – 301Iron (heme axial ligand)PROSITE-ProRule annotation
Metal bindingi91 – 911Iron (heme axial ligand)PROSITE-ProRule annotation

GO - Molecular functioni

  1. electron carrier activity Source: InterPro
  2. heme binding Source: InterPro
  3. iron ion binding Source: InterPro

GO - Biological processi

  1. oxidation-reduction process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Electron transport, Respiratory chain, Transport

Keywords - Ligandi

Heme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c
Gene namesi
Ordered Locus Names:TP02_0396
OrganismiTheileria parva (East coast fever infection agent)
Taxonomic identifieri5875 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaPiroplasmidaTheileriidaeTheileria
ProteomesiUP000001949: Unassembled WGS sequence

Organism-specific databases

EuPathDBiPiroplasmaDB:TP02_0396.

Subcellular locationi

Mitochondrion intermembrane space By similarity
Note: Loosely associated with the inner membrane.By similarity

GO - Cellular componenti

  1. mitochondrion Source: UniProtKB-KW
  2. respiratory chain Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 115115Cytochrome cPRO_0000273193Add
BLAST

Post-translational modificationi

Binds 1 heme group per subunit.By similarity

Proteomic databases

PRIDEiQ4N594.

Interactioni

Protein-protein interaction databases

STRINGi5875.TP02_0396.

Structurei

3D structure databases

ProteinModelPortaliQ4N594.
SMRiQ4N594. Positions 11-114.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome c family.Curated

Phylogenomic databases

eggNOGiCOG3474.
HOGENOMiHOG000009762.
InParanoidiQ4N594.
KOiK08738.

Family and domain databases

Gene3Di1.10.760.10. 1 hit.
InterProiIPR009056. Cyt_c-like_dom.
IPR002327. Cyt_c_1A/1B.
IPR003088. Cyt_c_dom.
[Graphical view]
PANTHERiPTHR11961. PTHR11961. 1 hit.
PfamiPF00034. Cytochrom_C. 1 hit.
[Graphical view]
PRINTSiPR00604. CYTCHRMECIAB.
SUPFAMiSSF46626. SSF46626. 1 hit.
PROSITEiPS51007. CYTC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4N594-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAKPEPDVVI PEGDSSKGAK LFKSKCAQCH TINKGGSVKQ GPNLYGFYGR
60 70 80 90 100
KSGASDYAYS DANKNSGIVW SDKHLFVYLV NPKQYIPGTK MVFAGLKKEQ
110
DRADLIAYLK EASSK
Length:115
Mass (Da):12,579
Last modified:August 2, 2005 - v1
Checksum:iD3E65A6FEB5448C0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAGK01000002 Genomic DNA. Translation: EAN32679.1.
RefSeqiXP_764962.1. XM_759869.1.

Genome annotation databases

GeneIDi3502047.
KEGGitpv:TP02_0396.

Cross-referencesi

Web resourcesi

Protein Spotlight

Life shuttle - Issue 76 of November 2006

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAGK01000002 Genomic DNA. Translation: EAN32679.1 .
RefSeqi XP_764962.1. XM_759869.1.

3D structure databases

ProteinModelPortali Q4N594.
SMRi Q4N594. Positions 11-114.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 5875.TP02_0396.

Proteomic databases

PRIDEi Q4N594.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3502047.
KEGGi tpv:TP02_0396.

Organism-specific databases

EuPathDBi PiroplasmaDB:TP02_0396.

Phylogenomic databases

eggNOGi COG3474.
HOGENOMi HOG000009762.
InParanoidi Q4N594.
KOi K08738.

Family and domain databases

Gene3Di 1.10.760.10. 1 hit.
InterProi IPR009056. Cyt_c-like_dom.
IPR002327. Cyt_c_1A/1B.
IPR003088. Cyt_c_dom.
[Graphical view ]
PANTHERi PTHR11961. PTHR11961. 1 hit.
Pfami PF00034. Cytochrom_C. 1 hit.
[Graphical view ]
PRINTSi PR00604. CYTCHRMECIAB.
SUPFAMi SSF46626. SSF46626. 1 hit.
PROSITEi PS51007. CYTC. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Muguga.

Entry informationi

Entry nameiCYC_THEPA
AccessioniPrimary (citable) accession number: Q4N594
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 23, 2007
Last sequence update: August 2, 2005
Last modified: October 29, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Protein Spotlight
    Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3