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Q4LEZ3 (AARD_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Alanine and arginine-rich domain-containing protein
Gene names
Name:AARD
Synonyms:C8orf85
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length155 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

Ontologies

Keywords
   Coding sequence diversityPolymorphism
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processlung development

Inferred from electronic annotation. Source: Ensembl

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 155155Alanine and arginine-rich domain-containing protein
PRO_0000337036

Regions

Compositional bias60 – 10546Ala/Arg-rich

Natural variations

Natural variant961G → R. Ref.2
Corresponds to variant rs16889283 [ dbSNP | Ensembl ].
VAR_043570

Sequences

Sequence LengthMass (Da)Tools
Q4LEZ3 [UniParc].

Last modified August 2, 2005. Version 1.
Checksum: 4D991ECA38D29531

FASTA15517,575
        10         20         30         40         50         60 
MGPGDFRRCR ERISQGLQGL PGRAELWFPP RPACDFFGDG RSTDIQEEAL AASPLLEDLR 

        70         80         90        100        110        120 
RRLTRAFQWA VQRAISRRVQ EAAAAAAARE EQSWTGVEAT LARLRAELVE MHFQNHQLAR 

       130        140        150 
TLLDLNMKVQ QLKKEYELEI TSDSQSPKDD AANPE 

« Hide

References

« Hide 'large scale' references
[1]"Novel gene containing alanine and arginine rich domain on human chromosome 8."
Ishikawa S.K., Shimizu A., Yamazaki S., Asakawa S., Shimizu N.
Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT ARG-96.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB181519 mRNA. Translation: BAE03184.1.
BC142621 mRNA. Translation: AAI42622.1.
CCDSCCDS34935.1.
RefSeqNP_001020528.1. NM_001025357.2.
UniGeneHs.437551.

3D structure databases

ProteinModelPortalQ4LEZ3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING9606.ENSP00000367528.

Polymorphism databases

DMDM121944377.

Proteomic databases

PaxDbQ4LEZ3.
PRIDEQ4LEZ3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000378279; ENSP00000367528; ENSG00000205002.
GeneID441376.
KEGGhsa:441376.
UCSCuc003yof.3. human.

Organism-specific databases

CTD441376.
GeneCardsGC08P117951.
HGNCHGNC:33842. AARD.
neXtProtNX_Q4LEZ3.
PharmGKBPA164717502.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG133760.
HOGENOMHOG000033743.
HOVERGENHBG101169.
InParanoidQ4LEZ3.
OMAFQWAVQR.
OrthoDBEOG7XWPQ8.
PhylomeDBQ4LEZ3.
TreeFamTF339066.

Gene expression databases

BgeeQ4LEZ3.
GenevestigatorQ4LEZ3.

Family and domain databases

ProtoNetSearch...

Other

NextBio110120.
PROQ4LEZ3.

Entry information

Entry nameAARD_HUMAN
AccessionPrimary (citable) accession number: Q4LEZ3
Secondary accession number(s): A5PKU8
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: August 2, 2005
Last modified: July 9, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human chromosome 8

Human chromosome 8: entries, gene names and cross-references to MIM