Reviewed, UniProtKB/Swiss-Prot Q4LEZ3 (AARD_HUMAN)

Names and origin

Protein names

Recommended name:
    Alanine and arginine-rich domain-containing protein

Gene names

Name:	AARD
Synonyms:	C8orf85

Organism

Homo sapiens (Human) [Complete proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	155 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

Ontologies

Keywords
Coding sequence diversity	Polymorphism
Technical term	Complete proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 155	155	Alanine and arginine-rich domain-containing protein		PRO_0000337036
Regions
	Compositional bias	60 – 105	46	Ala/Arg-rich
Natural variations
	Natural variant	96	1	G → R: dbSNP rs16889283. Ref.2		VAR_043570

Sequences

	Sequence		Length	Mass (Da)
	Q4LEZ3-1 [UniParc]. Last modified August 2, 2005. Version 1. Checksum: 4D991ECA38D29531	FASTA	155	17,575
	10 20 30 40 50 60 MGPGDFRRCR ERISQGLQGL PGRAELWFPP RPACDFFGDG RSTDIQEEAL AASPLLEDLR 70 80 90 100 110 120 RRLTRAFQWA VQRAISRRVQ EAAAAAAARE EQSWTGVEAT LARLRAELVE MHFQNHQLAR 130 140 150 TLLDLNMKVQ QLKKEYELEI TSDSQSPKDD AANPE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Novel gene containing alanine and arginine rich domain on human chromosome 8." Ishikawa S.K., Shimizu A., Yamazaki S., Asakawa S., Shimizu N. Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT ARG-96.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AB181519 mRNA. Translation: BAE03184.1. BC142621 mRNA. Translation: AAI42622.1.
IPI	IPI00455846.
RefSeq	NP_001020528.1.
UniGene	Hs.437551
3D structure databases
ModBase	Search...
Proteomic databases
PRIDE	Q4LEZ3.
Genome annotation databases
Ensembl	ENST00000378279; ENSP00000367528; ENSG00000205002; Homo sapiens. [Genome view]
GeneID	441376.
KEGG	hsa:441376.
UCSC	uc003yof.1. human.
Organism-specific databases
CTD	441376.
GeneCards	GC08P118019.
HGNC	HGNC:33842. C8orf85.
GenAtlas	Search...
Phylogenomic databases
HOGENOM	Q4LEZ3.
HOVERGEN	Q4LEZ3.
OMA	FPPRPAC
OrthoDB	EOG922D4J
Gene expression databases
Bgee	Q4LEZ3.
Genevestigator	Q4LEZ3.
Family and domain databases
ProtoNet	Search...
Other Resources
NextBio	110120.

Entry information

Entry name

AARD_HUMAN

Accession

Primary (citable) accession number: Q4LEZ3
Secondary accession number(s): A5PKU8

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	August 2, 2005
Last modified:	November 24, 2009
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.