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Q4LEZ3

- AARD_HUMAN

UniProt

Q4LEZ3 - AARD_HUMAN

Protein

Alanine and arginine-rich domain-containing protein

Gene

AARD

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 54 (01 Oct 2014)
      Sequence version 1 (02 Aug 2005)
      Previous versions | rss
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    Functioni

    GO - Biological processi

    1. lung development Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine and arginine-rich domain-containing protein
    Gene namesi
    Name:AARD
    Synonyms:C8orf85
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 8

    Organism-specific databases

    HGNCiHGNC:33842. AARD.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA164717502.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 155155Alanine and arginine-rich domain-containing proteinPRO_0000337036Add
    BLAST

    Proteomic databases

    PaxDbiQ4LEZ3.
    PRIDEiQ4LEZ3.

    Expressioni

    Gene expression databases

    BgeeiQ4LEZ3.
    GenevestigatoriQ4LEZ3.

    Interactioni

    Protein-protein interaction databases

    STRINGi9606.ENSP00000367528.

    Structurei

    3D structure databases

    ProteinModelPortaliQ4LEZ3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi60 – 10546Ala/Arg-richAdd
    BLAST

    Phylogenomic databases

    eggNOGiNOG133760.
    HOGENOMiHOG000033743.
    HOVERGENiHBG101169.
    InParanoidiQ4LEZ3.
    OMAiFQWAVQR.
    OrthoDBiEOG7XWPQ8.
    PhylomeDBiQ4LEZ3.
    TreeFamiTF339066.

    Sequencei

    Sequence statusi: Complete.

    Q4LEZ3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGPGDFRRCR ERISQGLQGL PGRAELWFPP RPACDFFGDG RSTDIQEEAL    50
    AASPLLEDLR RRLTRAFQWA VQRAISRRVQ EAAAAAAARE EQSWTGVEAT 100
    LARLRAELVE MHFQNHQLAR TLLDLNMKVQ QLKKEYELEI TSDSQSPKDD 150
    AANPE 155
    Length:155
    Mass (Da):17,575
    Last modified:August 2, 2005 - v1
    Checksum:i4D991ECA38D29531
    GO

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti96 – 961G → R.1 Publication
    Corresponds to variant rs16889283 [ dbSNP | Ensembl ].
    VAR_043570

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB181519 mRNA. Translation: BAE03184.1.
    BC142621 mRNA. Translation: AAI42622.1.
    CCDSiCCDS34935.1.
    RefSeqiNP_001020528.1. NM_001025357.2.
    UniGeneiHs.437551.

    Genome annotation databases

    EnsembliENST00000378279; ENSP00000367528; ENSG00000205002.
    GeneIDi441376.
    KEGGihsa:441376.
    UCSCiuc003yof.3. human.

    Polymorphism databases

    DMDMi121944377.

    Keywords - Coding sequence diversityi

    Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB181519 mRNA. Translation: BAE03184.1 .
    BC142621 mRNA. Translation: AAI42622.1 .
    CCDSi CCDS34935.1.
    RefSeqi NP_001020528.1. NM_001025357.2.
    UniGenei Hs.437551.

    3D structure databases

    ProteinModelPortali Q4LEZ3.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9606.ENSP00000367528.

    Polymorphism databases

    DMDMi 121944377.

    Proteomic databases

    PaxDbi Q4LEZ3.
    PRIDEi Q4LEZ3.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000378279 ; ENSP00000367528 ; ENSG00000205002 .
    GeneIDi 441376.
    KEGGi hsa:441376.
    UCSCi uc003yof.3. human.

    Organism-specific databases

    CTDi 441376.
    GeneCardsi GC08P117951.
    HGNCi HGNC:33842. AARD.
    neXtProti NX_Q4LEZ3.
    PharmGKBi PA164717502.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG133760.
    HOGENOMi HOG000033743.
    HOVERGENi HBG101169.
    InParanoidi Q4LEZ3.
    OMAi FQWAVQR.
    OrthoDBi EOG7XWPQ8.
    PhylomeDBi Q4LEZ3.
    TreeFami TF339066.

    Miscellaneous databases

    NextBioi 110120.
    PROi Q4LEZ3.

    Gene expression databases

    Bgeei Q4LEZ3.
    Genevestigatori Q4LEZ3.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "Novel gene containing alanine and arginine rich domain on human chromosome 8."
      Ishikawa S.K., Shimizu A., Yamazaki S., Asakawa S., Shimizu N.
      Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT ARG-96.

    Entry informationi

    Entry nameiAARD_HUMAN
    AccessioniPrimary (citable) accession number: Q4LEZ3
    Secondary accession number(s): A5PKU8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: August 2, 2005
    Last modified: October 1, 2014
    This is version 54 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 8
      Human chromosome 8: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations

    External Data

    Dasty 3