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Protein
Submitted name:

DSP variant protein

Gene

DSP variant protein

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
DSP variant proteinImported
Gene namesi
Name:DSP variant proteinImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PeptideAtlasiQ4LE79.
PRIDEiQ4LE79.

Expressioni

Gene expression databases

BgeeiENSG00000096696.

Interactioni

Protein-protein interaction databases

MINTiMINT-5005808.

Structurei

3D structure databases

ProteinModelPortaliQ4LE79.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili458 – 488Sequence analysisAdd BLAST31
Coiled coili1102 – 1143Sequence analysisAdd BLAST42
Coiled coili1151 – 1199Sequence analysisAdd BLAST49
Coiled coili1218 – 1367Sequence analysisAdd BLAST150

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

HOGENOMiHOG000112198.
HOVERGENiHBG081434.

Family and domain databases

Gene3Di3.90.1290.10. 5 hits.
InterProiIPR028462. Desmoplakin.
IPR001101. Plectin_repeat.
IPR018159. Spectrin/alpha-actinin.
[Graphical view]
PANTHERiPTHR11915:SF234. PTHR11915:SF234. 1 hit.
PfamiPF00681. Plectin. 8 hits.
[Graphical view]
SMARTiSM00250. PLEC. 18 hits.
SM00150. SPEC. 3 hits.
[Graphical view]
SUPFAMiSSF75399. SSF75399. 5 hits.

Sequencei

Sequence statusi: Fragment.

Q4LE79-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
RAATSRAFRT PARFPGRPPI LGPLRFLRAG PPRLCLGAEP LSRLPADMSC
60 70 80 90 100
NGGSHPRINT LGRMIRAESG PDLRYEVTSG GGGTSRMYYS RRGVITDQNS
110 120 130 140 150
DGYCQTGTMS RHQNQNTIQE LLQNCSDCLM RAELIVQPEL KYGDGIQLTR
160 170 180 190 200
SRELDECFAQ ANDQMEILDS LIREMRQMGQ PCDAYQKRLL QLQEQMRALY
210 220 230 240 250
KAISVPRVRR ASSKGGGGYT CQSGSGWDEF TKHVTSECLG WMRQQRAEMD
260 270 280 290 300
MVAWGVDLAS VEQHINSHRG IHNSIGDYRW QLDKIKADLR EKSAIYQLEE
310 320 330 340 350
EYENLLKASF ERMDHLRQLQ NIIQATSREI MWINDCEEEE LLYDWSDKNT
360 370 380 390 400
NIAQKQEAFS IRMSQLEVKE KELNKLKQES DQLVLNQHPA SDKIEAYMDT
410 420 430 440 450
LQTQWSWILQ ITKCIDVHLK ENAAYFQFFE EAQSTEAYLK GLQDSIRKKY
460 470 480 490 500
PCDKNMPLQH LLEQIKELEK EREKILEYKR QVQNLVNKSK KIVQLKPRNP
510 520 530 540 550
DYRSNKPIIL RALCDYKQDQ KIVHKGDECI LKDNNERSKW YVTGPGGVDM
560 570 580 590 600
LVPSVGLIIP PPNPLAVDLS CKIEQYYEAI LALWNQLYIN MKSLVSWHYC
610 620 630 640 650
MIDIEKIRAM TIAKLKTMRQ EDYMKTIADL ELHYQEFIRN SQGSEMFGDD
660 670 680 690 700
DKRKIQSQFT DAQKHYQTLV IQLPGYPQHQ TVTTTEITHH GTCQDVNHNK
710 720 730 740 750
VIETNRENDK QETWMLMELQ KIRRQIEHCE GRMTLKNLPL ADQGSSHHIT
760 770 780 790 800
VKINELKSVQ NDSQAIAEVL NQLKDMLANF RGSEKYCYLQ NEVFGLFQKL
810 820 830 840 850
ENINGVTDGY LNSLCTVRAL LQAILQTEDM LKVYEARLTE EETVCLDLDK
860 870 880 890 900
VEAYRCGLKK IKNDLNLKKS LLATMKTELQ KAQQIHSQTS QQYPLYDLDL
910 920 930 940 950
GKFGEKVTQL TDRWQRIDKQ IDFRLWDLEK QIKQLRNYRD NYQAFCKWLY
960 970 980 990 1000
DAKRRQDSLE SMKFGDSNTV MRFLNEQKNL HSEISGKRDK SEEVQKIAEL
1010 1020 1030 1040 1050
CANSIKDYEL QLASYTSGLE TLLNIPIKRT MIQSPSGVIL QEAADVHARY
1060 1070 1080 1090 1100
IELLTRSGDY YRFLSEMLKS LEDLKLKNTK IEVLEEELRL ARDANSENCN
1110 1120 1130 1140 1150
KNKFLDQNLQ KYQAECSQFK AKLASLEELK RQAELDGKSA KQNLDKCYGQ
1160 1170 1180 1190 1200
IKELNEKITR LTYEIEDEKR RRKSVEDRFD QQKNDYDQLQ KARQCEKENL
1210 1220 1230 1240 1250
GWQKLESEKA IKEKEYEIER LRVLLQEEGT RKREYENELA KASNRIQESK
1260 1270 1280 1290 1300
NQCTQVVQER ESLLVKIKVL EQDKARLQRL EDELNRAKST LEAETRVKQR
1310 1320 1330 1340 1350
LECEKQQIQN DLNQWKTQYS RKEEAIRKIE SEREKSEREK NSLRSEIERL
1360 1370 1380 1390 1400
QAEIKRIEER CRRKLEDSTR ETQSQLETER SRYQREIDKL RQRPYGSHRE
1410 1420 1430 1440 1450
TQTECEWTVD TSKLVFDGLR KKVTAMQLYE CQLIDKTTLD KLLKGKKSVE
1460 1470 1480 1490 1500
EVASEIQPFL RGAGSIAGAS ASPKEKYSLV EAKRKKLISP ESTVMLLEAQ
1510 1520 1530 1540 1550
AATGGIIDPH RNEKLTVDSA IARDLIDFDD RQQIYAAEKA ITGFDDPFSG
1560 1570 1580 1590 1600
KTVSVSEAIK KNLIDRETGM RLLEAQIASG GVVDPVNSVF LPKDVALARG
1610 1620 1630 1640 1650
LIDRDLYRSL NDPRDSQKNF VDPVTKKKVS YVQLKERCRI EPHTGLLLLS
1660 1670 1680 1690 1700
VQKRSMSFQG IRQPVTVTEL VDSGILRPST VNELESGQIS YDEVGERIKD
1710 1720 1730 1740 1750
FLQGSSCIAG IYNETTKQKL GIYEAMKIGL VRPGTALELL EAQAATGFIV
1760 1770 1780 1790 1800
DPVSNLRLPV EEAYKRGLVG IEFKEKLLSA ERAVTGYNDP ETGNIISLFQ
1810 1820 1830 1840 1850
AMNKELIEKG HGIRLLEAQI ATGGIIDPKE SHRLPVDIAY KRGYFNEELS
1860 1870 1880 1890 1900
EILSDPSDDT KGFFDPNTEE NLTYLQLKER CIKDEETGLC LLPLKEKKKQ
1910 1920 1930 1940 1950
VQTSQKNTLR KRRVVIVDPE TNKEMSVQEA YKKGLIDYET FKELCEQECE
1960 1970 1980 1990 2000
WEEITITGSD GSTRVVLVDR KTGSQYDIQD AIDKGLVDRK FFDQYRSGSL
2010 2020 2030 2040 2050
SLTQFADMIS LKNGVGTSSS MGSGVSDDVF SSSRHESVSK ISTISSVRNL
2060 2070 2080 2090 2100
TIRSSSFSDT LEESSPIAAI FDTENLEKIS ITEGIERGIV DSITGQRLLE
2110 2120 2130 2140 2150
AQACTGGIIH PTTGQKLSLQ DAVSQGVIDQ DMATRLKPAQ KAFIGFEGVK
2160 2170 2180 2190 2200
GKKKMSAAEA VKEKWLPYEA GQRFLEFQYL TGGLVDPEVH GRISTEEAIR
2210 2220 2230 2240 2250
KGFIDGRAAQ RLQDTSSYAK ILTCPKTKLK ISYKDAINRS MVEDITGLRL
2260 2270 2280 2290 2300
LEAASVSSKG LPSPYNMSSA PGSRSGSRSG SRSGSRSGSR SGSRRGSFDA
2310
TGNSSYSYSY SFSSSSIGH
Length:2,319
Mass (Da):265,195
Last modified:August 2, 2005 - v1
Checksum:iA226A8D19C52AF27
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB209992 mRNA. Translation: BAE06074.1.
RefSeqiNP_001008844.1. NM_001008844.2.
UniGeneiHs.519873.

Genome annotation databases

GeneIDi1832.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB209992 mRNA. Translation: BAE06074.1.
RefSeqiNP_001008844.1. NM_001008844.2.
UniGeneiHs.519873.

3D structure databases

ProteinModelPortaliQ4LE79.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-5005808.

Proteomic databases

PeptideAtlasiQ4LE79.
PRIDEiQ4LE79.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1832.

Organism-specific databases

CTDi1832.

Phylogenomic databases

HOGENOMiHOG000112198.
HOVERGENiHBG081434.

Miscellaneous databases

ChiTaRSiDSP. human.
GenomeRNAii1832.

Gene expression databases

BgeeiENSG00000096696.

Family and domain databases

Gene3Di3.90.1290.10. 5 hits.
InterProiIPR028462. Desmoplakin.
IPR001101. Plectin_repeat.
IPR018159. Spectrin/alpha-actinin.
[Graphical view]
PANTHERiPTHR11915:SF234. PTHR11915:SF234. 1 hit.
PfamiPF00681. Plectin. 8 hits.
[Graphical view]
SMARTiSM00250. PLEC. 18 hits.
SM00150. SPEC. 3 hits.
[Graphical view]
SUPFAMiSSF75399. SSF75399. 5 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiQ4LE79_HUMAN
AccessioniPrimary (citable) accession number: Q4LE79
Entry historyi
Integrated into UniProtKB/TrEMBL: August 2, 2005
Last sequence update: August 2, 2005
Last modified: September 7, 2016
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.