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Unreviewed, UniProtKB/TrEMBL Q4LE51 (Q4LE51_HUMAN)

Last modified January 19, 2010. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information

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Names and origin

Protein namesSubmitted name:
    PIK3CA variant protein EMBL BAE06102.1
Gene names
Name: PIK3CA variant protein EMBL BAE06102.1
OrganismHomo sapiens (Human) EMBL BAE06102.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

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Protein attributes

Sequence length1069 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level.

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General annotation (Comments)

Sequence similarities

Contains 1 PI3K/PI4K domain.

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL BAE06102.1

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Sequences

Sequence LengthMass (Da)Tools
Q4LE51-1 [UniParc].

Last modified August 2, 2005. Version 1.
Checksum: 68624049DF9E4352

FASTA1,069124,385
        10         20         30         40         50         60 
TMPPRPSSGE LWGIHLMPPR ILVECLLPNG MIVTLECLRE ATLITIKHEL FKEARKYPLH 

        70         80         90        100        110        120 
QLLQDESSYI FVSVTQEAER EEFFDETRRL CDLRLFQPFL KVIEPVGNRE EKILNREIGF 

       130        140        150        160        170        180 
AIGMPVCEFD MVKDPEVQDF RRNILNVCKE AVDLRDLNSP HSRAMYVYPP NVESSPELPK 

       190        200        210        220        230        240 
HIYNKLDKGQ IIVVIWVIVS PNNDKQKYTL KINHDCVPEQ VIAEAIRKKT RSMLLSSEQL 

       250        260        270        280        290        300 
KLCVLEYQGK YILKVCGCDE YFLEKYPLSQ YKYIRSCIML GRMPNLMLMA KESLYSQLPM 

       310        320        330        340        350        360 
DCFTMPSYSR RISTATPYMN GETSTKSLWV INSALRIKIL CATYVNVNIR DIDKIYVRTG 

       370        380        390        400        410        420 
IYHGGEPLCD NVNTQRVPCS NPRWNEWLNY DIYIPDLPRA ARLCLSICSV KGRKGAKEEH 

       430        440        450        460        470        480 
CPLAWGNINL FDYTDTLVSG KMALNLWPVP HGLEDLLNPI GVTGSNPNKE TPCLELEFDW 

       490        500        510        520        530        540 
FSSVVKFPDM SVIEEHANWS VSREAGFSYS HAGLSNRLAR DNELRENDKE QLKAISTRDP 

       550        560        570        580        590        600 
LSEITEQEKD FLWSHRHYCV TIPEILPKLL LSVKWNSRDE VAQMYCLVKD WPPIKPEQAM 

       610        620        630        640        650        660 
ELLDCNYPDP MVRGFAVRCL EKYLTDDKLS QYLIQLVQVL KYEQYLDNLL VRFLLKKALT 

       670        680        690        700        710        720 
NQRIGHFFFW HLKSEMHNKT VSQRFGLLLE SYCRACGMYL KHLNRQVEAM EKLINLTDIL 

       730        740        750        760        770        780 
KQEKKDETQK VQMKFLVEQM RRPDFMDALQ GFLSPLNPAH QLGNLRLEEC RIMSSAKRPL 

       790        800        810        820        830        840 
WLNWENPDIM SELLFQNNEI IFKNGDDLRQ DMLTLQIIRI MENIWQNQGL DLRMLPYGCL 

       850        860        870        880        890        900 
SIGDCVGLIE VVRNSHTIMQ IQCKGGLKGA LQFNSHTLHQ WLKDKNKGEI YDAAIDLFTR 

       910        920        930        940        950        960 
SCAGYCVATF ILGIGDRHNS NIMVKDDGQL FHIDFGHFLD HKKKKFGYKR ERVPFVLTQD 

       970        980        990       1000       1010       1020 
FLIVISKGAQ ECTKTREFER FQEMCYKAYL AIRQHANLFI NLFSMMLGSG MPELQSFDDI 

      1030       1040       1050       1060 
AYIRKTLALD KTEQEALEYF MKQMNDAHHG GWTTKMDWIF HTIKQHALN

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References

[1]"Preparation of a set of expression-ready clones of mammalian long cDNAs encoding large proteins by the ORF trap cloning method."
Nakajima D., Saito K., Yamakawa H., Kikuno R.F., Nakayama M., Ohara R., Okazaki N., Koga H., Nagase T., Ohara O.
Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Brain EMBL BAE06102.1.
+Additional computationally mapped references.

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AB210020 mRNA. Translation: BAE06102.1.
IPIIPI00031386.
UniGeneHs.553498
Hs.85701

3D structure databases

SMRQ4LE51. Positions 17-106, 334-482.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ4LE51.

Proteomic databases

PRIDEQ4LE51.

Genome annotation databases

EnsemblENST00000263967; ENSP00000263967; ENSG00000121879; Homo sapiens. [Genome view]

Organism-specific databases

HGNCHGNC:8975. PIK3CA.
GenAtlasSearch...

Phylogenomic databases

HOGENOMHBG445499.
HOVERGENQ4LE51.
OrthoDBEOG9DFS7D.

Gene expression databases

ArrayExpressQ4LE51.
BgeeQ4LE51.

Family and domain databases

InterProIPR016024. ARM-type_fold.
IPR000008. C2_Ca-dep.
IPR008973. C2_Ca/lipid-bd_dom_CaLB.
IPR011009. Kinase-like_dom.
IPR000403. PI3/4_kinase_cat.
IPR018936. PI3/4_kinase_CS.
IPR002420. PI3K_C2.
IPR003113. PI3K_p85_bd.
IPR000341. PI3K_ras_bd.
IPR015433. PI_Kinase.
IPR001263. PInositide-3_kin_accessory_dom.
[Graphical view]
Gene3DG3DSA:1.10.1070.11. PI3/4_kinase_cat. 1 hit.
G3DSA:1.25.40.70. PI3Ka. 1 hit.
PANTHERPTHR10048. PI_Kinase. 1 hit.
PfamPF00454. PI3_PI4_kinase. 1 hit.
PF00792. PI3K_C2. 1 hit.
PF02192. PI3K_p85B. 1 hit.
PF00794. PI3K_rbd. 1 hit.
PF00613. PI3Ka. 1 hit.
[Graphical view]
SMARTSM00239. C2. 1 hit.
SM00142. PI3K_C2. 1 hit.
SM00143. PI3K_p85B. 1 hit.
SM00144. PI3K_rbd. 1 hit.
SM00145. PI3Ka. 1 hit.
SM00146. PI3Kc. 1 hit.
[Graphical view]
PROSITEPS00915. PI3_4_KINASE_1. 1 hit.
PS00916. PI3_4_KINASE_2. 1 hit.
PS50290. PI3_4_KINASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameQ4LE51_HUMAN
AccessionPrimary (citable) accession number: Q4LE51
Entry history
Integrated into UniProtKB/TrEMBL: August 2, 2005
Last sequence update: August 2, 2005
Last modified: January 19, 2010
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information