Q4LE27 (Q4LE27_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
ABCA3 variant protein EMBL BAE06126.1

Gene names

Name:

ABCA3 variant protein EMBL BAE06126.1

Organism

Homo sapiens (Human) EMBL BAE06126.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	1708 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the ABC transporter superfamily. RuleBase RU000684

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU000684 Nucleotide-binding
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL BAE06126.1

Sequences

	Sequence		Length	Mass (Da)
	Q4LE27 [UniParc]. Last modified August 2, 2005. Version 1. Checksum: E64C1D2ACEDA199B	FASTA	1,708	191,318
	10 20 30 40 50 60 TAPPPSPSLP LQDRAATSAH LALFTLSFQS TFLLFPAGCS AYLNLLRPPT SLAALGVPFS 70 80 90 100 110 120 KTMAVLRQLA LLLWKNYTLQ KRKVLVTVLE LFLPLLFSGI LIWLRLKIQS ENVPNATIYP 130 140 150 160 170 180 GQSIQELPLF FTFPPPGDTW ELAYIPSHSD AAKTVTETVR RALVINMRVR GFPSEKDFED 190 200 210 220 230 240 YIRYDNCSSS VLAAVVFEHP FNHSKEPLPL AVKYHLRFSY TRRNYMWTQT GSFFLKETEG 250 260 270 280 290 300 WHTTSLFPLF PNPGPREPTS PDGGEPGYIR EGFLAVQHAV DRAIMEYHAD AATRQLFQRL 310 320 330 340 350 360 TVTIKRFPYP PFIADPFLVA IQYQLPLLLL LSFTYTALTI ARAVVQEKER RLKEYMRMMG 370 380 390 400 410 420 LSSWLHWSAW FLLFFLFLLI AASFMTLLFC VKVKPNVAVL SRSDPSLVLA FLLCFAISTI 430 440 450 460 470 480 SFSFMVSTFF SKGMGIQWRD LLSPVNVDDD FCFGQVLGML LLDSVLYGLV TWYMEAVFPG 490 500 510 520 530 540 QFGVPQPWYF FIMPSYWCGK PRAVAGKEEE DSDPEKALRN EYFEAEPEDL VAGIKIKHLS 550 560 570 580 590 600 KVFRVGNKDR AAVRDLNLNL YEGQITVLLG HNGAGKTTTL SMLTGLFPPT SGRAYISGYE 610 620 630 640 650 660 ISQDMVQIRK SLGLCPQHDI LFDNLTVAEH LYFYAQLKGL SRQKCPEEVK QMLHIIGLED 670 680 690 700 710 720 KWNSRSRFLS GGMRRKLSIG IALIAGSKVL ILDEPTSGMD AISRRAIWDL LQRQKSDRTI 730 740 750 760 770 780 VLTTHFMDEA DLLGDRIAIM AKGELQCCGS SLFLKQKYGA GYHMTLVKEP HCNPEDISQL 790 800 810 820 830 840 VHHHVPNATL ESSAGAELSF ILPRESTHRF EGLFAKLEKK QKELGIASFG ASITTMEEVF 850 860 870 880 890 900 LRVGKLVDSS MDIQAIQLPA LQYQHERRAS DWAVDSNLCG AMDPSDGIGA LIEEERTAVK 910 920 930 940 950 960 LNTGLALHCQ QFWAMFLKKA AYSWREWKMV AAQVLVPLTC VTLALLAINY SSELFDDPML 970 980 990 1000 1010 1020 RLTLGEYGRT VVPFSVPGTS QLGQQLSEHL KDALQAEGQE PREVLGDLEE FLIFRASVEG 1030 1040 1050 1060 1070 1080 GGFNERCLVA ASFRDVGERT VVNALFNNQA YHSPATALAV VDNLLFKLLC GPHASIVVSN 1090 1100 1110 1120 1130 1140 FPQPRSALQA AKDQFNEGRK GFDIALNLLF AMAFLASTFS ILAVSERAVQ AKHVQFVSGV 1150 1160 1170 1180 1190 1200 HVASFWLSAL LWDLISFLIP SLLLLVVFKA FDVRAFTRDG HMADTLLLLL LYGWAIIPLM 1210 1220 1230 1240 1250 1260 YLMNFFFLGA ATAYTRLTIF NILSGIATFL MVTIMRIPAV KLEELSKTLD HVFLVLPNHC 1270 1280 1290 1300 1310 1320 LGMAVSSFYE NYETRRYCTS SEVAAHYCKK YNIQYQENFY AWSAPGVGRF VASMAASGCA 1330 1340 1350 1360 1370 1380 YLILLFLIET NLLQRLRGIL CALRRRRTLT ELYTRMPVLP EDQDVADERT RILAPSPDSL 1390 1400 1410 1420 1430 1440 LHTPLIIKEL SKVYEQRVPL LAVDRLSLAV QKGECFGLLG FNGAGKTTTF KMLTGEESLT 1450 1460 1470 1480 1490 1500 SGDAFVGGHR ISSDVGKVRQ RIGYCPQFDA LLDHMTGREM LVMYARLRGI PERHIGACVE 1510 1520 1530 1540 1550 1560 NTLRGLLLEP HANKLVRTYS GGNKRKLSTG IALIGEPAVI FLDEPSTGMD PVARRLLWDT 1570 1580 1590 1600 1610 1620 VARARESGKA IIITSHSMEE CEALCTRLAI MVQGQFKCLG SPQHLKSKFG SGYSLRAKVQ 1630 1640 1650 1660 1670 1680 SEGQQEALEE FKAFVDLTFP GSVLEDEHQG MVHYHLPGRD LSWAKVFGIL EKAKEKYGVD 1690 1700 DYSVSQISLE QVFLSFAHLQ PPTAEEGR

References

[1]	"Preparation of a set of expression-ready clones of mammalian long cDNAs encoding large proteins by the ORF trap cloning method." Nakajima D., Saito K., Yamakawa H., Kikuno R.F., Nakayama M., Ohara R., Okazaki N., Koga H., Nagase T., Ohara O. Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Brain EMBL BAE06126.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB210044 mRNA. Translation: BAE06126.1.
IPI	IPI00619902.
RefSeq	NP_001080.2. NM_001089.2.
UniGene	Hs.26630.
3D structure databases
ProteinModelPortal	Q4LE27.
ModBase	Search...
Protein-protein interaction databases
STRING	Q4LE27.
Proteomic databases
PRIDE	Q4LE27.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	21.
KEGG	hsa:21.
UCSC	uc010bsk.1. human.
Organism-specific databases
CTD	21.
PharmGKB	PA24378.
Phylogenomic databases
eggNOG	prNOG09946.
HOGENOM	HBG444243.
HOVERGEN	HBG050435.
OMA	NIQYQEN.
PhylomeDB	Q4LE27.
Gene expression databases
ArrayExpress	Q4LE27.
Bgee	Q4LE27.
Family and domain databases
InterPro	IPR003439. ABC_transporter-like. IPR017871. ABC_transporter_CS. IPR003593. ATPase_AAA+_core. [Graphical view]
KO	K05643.
Pfam	PF00005. ABC_tran. 2 hits. [Graphical view]
SMART	SM00382. AAA. 2 hits. [Graphical view]
PROSITE	PS00211. ABC_TRANSPORTER_1. 1 hit. PS50893. ABC_TRANSPORTER_2. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q4LE27_HUMAN

Accession

Primary (citable) accession number: Q4LE27

Entry history

Integrated into UniProtKB/TrEMBL:	August 2, 2005
Last sequence update:	August 2, 2005
Last modified:	December 14, 2011
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.