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Q4LDE5

- SVEP1_HUMAN

UniProt

Q4LDE5 - SVEP1_HUMAN

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Protein

Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1

Gene

SVEP1

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Functioni

May play a role in the cell attachment process.By similarity

GO - Molecular functioni

  1. calcium ion binding Source: InterPro
  2. chromatin binding Source: Ensembl

GO - Biological processi

  1. cell adhesion Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Cell adhesion

Keywords - Ligandi

Calcium

Names & Taxonomyi

Protein namesi
Recommended name:
Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1
Alternative name(s):
CCP module-containing protein 22
Polydom
Selectin-like osteoblast-derived protein
Short name:
SEL-OB
Serologically defined breast cancer antigen NY-BR-38
Gene namesi
Name:SVEP1
Synonyms:C9orf13, CCP22, SELOB
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 9

Organism-specific databases

HGNCiHGNC:15985. SVEP1.

Subcellular locationi

Secreted Curated. Cytoplasm 1 Publication. Membrane 1 Publication; Peripheral membrane protein 1 Publication

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
  2. extracellular region Source: UniProtKB-KW
  3. membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Membrane, Secreted

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA25971.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1717Sequence AnalysisAdd
BLAST
Chaini18 – 35713554Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1PRO_0000320179Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi186 – 1861N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi378 ↔ 420By similarity
Disulfide bondi406 ↔ 433By similarity
Disulfide bondi438 ↔ 480By similarity
Disulfide bondi466 ↔ 493By similarity
Disulfide bondi498 ↔ 544By similarity
Disulfide bondi529 ↔ 559By similarity
Disulfide bondi727 ↔ 769By similarity
Disulfide bondi753 ↔ 787By similarity
Glycosylationi847 – 8471N-linked (GlcNAc...)Sequence Analysis
Glycosylationi1102 – 11021N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi1197 ↔ 1208By similarity
Disulfide bondi1202 ↔ 1217By similarity
Disulfide bondi1219 ↔ 1228By similarity
Disulfide bondi1235 ↔ 1246By similarity
Disulfide bondi1240 ↔ 1255By similarity
Disulfide bondi1257 ↔ 1266By similarity
Disulfide bondi1273 ↔ 1284By similarity
Disulfide bondi1278 ↔ 1293By similarity
Disulfide bondi1295 ↔ 1304By similarity
Disulfide bondi1311 ↔ 1322By similarity
Disulfide bondi1316 ↔ 1331By similarity
Disulfide bondi1333 ↔ 1342By similarity
Disulfide bondi1349 ↔ 1360By similarity
Disulfide bondi1354 ↔ 1369By similarity
Disulfide bondi1371 ↔ 1380By similarity
Disulfide bondi1387 ↔ 1398By similarity
Disulfide bondi1392 ↔ 1407By similarity
Disulfide bondi1409 ↔ 1418By similarity
Disulfide bondi1631 ↔ 1672By similarity
Disulfide bondi1658 ↔ 1685By similarity
Disulfide bondi1690 ↔ 1730By similarity
Disulfide bondi1716 ↔ 1743By similarity
Disulfide bondi1749 ↔ 1761By similarity
Disulfide bondi1755 ↔ 1770By similarity
Disulfide bondi1772 ↔ 1783By similarity
Disulfide bondi1789 ↔ 1829By similarity
Disulfide bondi1815 ↔ 1842By similarity
Disulfide bondi1847 ↔ 1887By similarity
Disulfide bondi1873 ↔ 1900By similarity
Disulfide bondi1905 ↔ 1945By similarity
Disulfide bondi1931 ↔ 1958By similarity
Disulfide bondi1963 ↔ 2003By similarity
Disulfide bondi1989 ↔ 2016By similarity
Disulfide bondi2021 ↔ 2061By similarity
Disulfide bondi2047 ↔ 2078By similarity
Disulfide bondi2083 ↔ 2126By similarity
Disulfide bondi2112 ↔ 2141By similarity
Disulfide bondi2146 ↔ 2186By similarity
Disulfide bondi2172 ↔ 2199By similarity
Disulfide bondi2204 ↔ 2245By similarity
Disulfide bondi2231 ↔ 2259By similarity
Disulfide bondi2264 ↔ 2304By similarity
Disulfide bondi2290 ↔ 2318By similarity
Disulfide bondi2323 ↔ 2363By similarity
Disulfide bondi2349 ↔ 2376By similarity
Disulfide bondi2381 ↔ 2422By similarity
Disulfide bondi2408 ↔ 2435By similarity
Disulfide bondi2440 ↔ 2480By similarity
Disulfide bondi2466 ↔ 2493By similarity
Disulfide bondi2498 ↔ 2538By similarity
Disulfide bondi2524 ↔ 2551By similarity
Disulfide bondi2556 ↔ 2596By similarity
Disulfide bondi2582 ↔ 2608By similarity
Disulfide bondi2685 ↔ 2712By similarity
Disulfide bondi2717 ↔ 2757By similarity
Disulfide bondi2743 ↔ 2770By similarity
Disulfide bondi2775 ↔ 2815By similarity
Disulfide bondi2801 ↔ 2828By similarity
Disulfide bondi2833 ↔ 2873By similarity
Disulfide bondi2859 ↔ 2886By similarity
Disulfide bondi2891 ↔ 2931By similarity
Disulfide bondi2917 ↔ 2944By similarity
Disulfide bondi2949 ↔ 2989By similarity
Disulfide bondi2975 ↔ 3002By similarity
Disulfide bondi3007 ↔ 3046By similarity
Glycosylationi3018 – 30181N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi3032 ↔ 3059By similarity
Disulfide bondi3064 ↔ 3104By similarity
Disulfide bondi3090 ↔ 3117By similarity
Disulfide bondi3122 ↔ 3163By similarity
Disulfide bondi3148 ↔ 3176By similarity
Disulfide bondi3181 ↔ 3221By similarity
Glycosylationi3186 – 31861N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi3207 ↔ 3236By similarity
Disulfide bondi3241 ↔ 3281By similarity
Disulfide bondi3267 ↔ 3294By similarity
Disulfide bondi3299 ↔ 3339By similarity
Disulfide bondi3325 ↔ 3352By similarity
Disulfide bondi3384 ↔ 3411By similarity
Disulfide bondi3416 ↔ 3456By similarity
Disulfide bondi3442 ↔ 3468By similarity
Disulfide bondi3504 ↔ 3514By similarity
Disulfide bondi3508 ↔ 3520By similarity
Disulfide bondi3522 ↔ 3531By similarity
Disulfide bondi3536 ↔ 3546By similarity
Disulfide bondi3540 ↔ 3552By similarity
Disulfide bondi3554 ↔ 3563By similarity

Post-translational modificationi

O-glycosylated with core 1 or possibly core 8 glycans.1 Publication

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

MaxQBiQ4LDE5.
PaxDbiQ4LDE5.
PRIDEiQ4LDE5.

PTM databases

PhosphoSiteiQ4LDE5.

Expressioni

Tissue specificityi

Present in mesenchymal primary cultured cell lysates (at protein level). Highly expressed in placenta. Also expressed in marrow stromal cell. Weakly or not expressed in other tissues.2 Publications

Gene expression databases

BgeeiQ4LDE5.
GenevestigatoriQ4LDE5.

Organism-specific databases

HPAiHPA020610.
HPA021520.

Interactioni

Protein-protein interaction databases

BioGridi123051. 4 interactions.
IntActiQ4LDE5. 12 interactions.
MINTiMINT-1197821.

Structurei

3D structure databases

ProteinModelPortaliQ4LDE5.
SMRiQ4LDE5. Positions 79-255, 281-507, 1195-1422, 1445-3563.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini83 – 264182VWFAPROSITE-ProRule annotationAdd
BLAST
Domaini376 – 43560Sushi 1PROSITE-ProRule annotationAdd
BLAST
Domaini436 – 49560Sushi 2PROSITE-ProRule annotationAdd
BLAST
Domaini496 – 56166Sushi 3PROSITE-ProRule annotationAdd
BLAST
Domaini560 – 64283HYR 1PROSITE-ProRule annotationAdd
BLAST
Domaini643 – 72482HYR 2PROSITE-ProRule annotationAdd
BLAST
Domaini725 – 78965Sushi 4PROSITE-ProRule annotationAdd
BLAST
Domaini1193 – 122937EGF-like 1PROSITE-ProRule annotationAdd
BLAST
Domaini1231 – 126737EGF-like 2; calcium-bindingPROSITE-ProRule annotationAdd
BLAST
Domaini1269 – 130537EGF-like 3; calcium-bindingPROSITE-ProRule annotationAdd
BLAST
Domaini1307 – 134337EGF-like 4; calcium-bindingPROSITE-ProRule annotationAdd
BLAST
Domaini1345 – 138137EGF-like 5; calcium-bindingPROSITE-ProRule annotationAdd
BLAST
Domaini1383 – 141937EGF-like 6; calcium-bindingPROSITE-ProRule annotationAdd
BLAST
Domaini1430 – 1623194PentaxinAdd
BLAST
Domaini1629 – 168759Sushi 5PROSITE-ProRule annotationAdd
BLAST
Domaini1688 – 174558Sushi 6PROSITE-ProRule annotationAdd
BLAST
Domaini1745 – 178440EGF-like 7; calcium-bindingPROSITE-ProRule annotationAdd
BLAST
Domaini1787 – 184458Sushi 7PROSITE-ProRule annotationAdd
BLAST
Domaini1845 – 190258Sushi 8PROSITE-ProRule annotationAdd
BLAST
Domaini1903 – 196058Sushi 9PROSITE-ProRule annotationAdd
BLAST
Domaini1961 – 201858Sushi 10PROSITE-ProRule annotationAdd
BLAST
Domaini2019 – 208062Sushi 11PROSITE-ProRule annotationAdd
BLAST
Domaini2081 – 214363Sushi 12PROSITE-ProRule annotationAdd
BLAST
Domaini2144 – 220158Sushi 13PROSITE-ProRule annotationAdd
BLAST
Domaini2202 – 226160Sushi 14PROSITE-ProRule annotationAdd
BLAST
Domaini2262 – 232059Sushi 15PROSITE-ProRule annotationAdd
BLAST
Domaini2321 – 237858Sushi 16PROSITE-ProRule annotationAdd
BLAST
Domaini2379 – 243759Sushi 17PROSITE-ProRule annotationAdd
BLAST
Domaini2438 – 249558Sushi 18PROSITE-ProRule annotationAdd
BLAST
Domaini2496 – 255358Sushi 19PROSITE-ProRule annotationAdd
BLAST
Domaini2554 – 261057Sushi 20PROSITE-ProRule annotationAdd
BLAST
Domaini2663 – 271452Sushi 21PROSITE-ProRule annotationAdd
BLAST
Domaini2715 – 277258Sushi 22PROSITE-ProRule annotationAdd
BLAST
Domaini2773 – 283058Sushi 23PROSITE-ProRule annotationAdd
BLAST
Domaini2831 – 288858Sushi 24PROSITE-ProRule annotationAdd
BLAST
Domaini2889 – 294658Sushi 25PROSITE-ProRule annotationAdd
BLAST
Domaini2947 – 300458Sushi 26PROSITE-ProRule annotationAdd
BLAST
Domaini3005 – 306157Sushi 27PROSITE-ProRule annotationAdd
BLAST
Domaini3062 – 311958Sushi 28PROSITE-ProRule annotationAdd
BLAST
Domaini3120 – 317859Sushi 29PROSITE-ProRule annotationAdd
BLAST
Domaini3179 – 323860Sushi 30PROSITE-ProRule annotationAdd
BLAST
Domaini3239 – 329658Sushi 31PROSITE-ProRule annotationAdd
BLAST
Domaini3297 – 335458Sushi 32PROSITE-ProRule annotationAdd
BLAST
Domaini3355 – 341359Sushi 33PROSITE-ProRule annotationAdd
BLAST
Domaini3414 – 347057Sushi 34PROSITE-ProRule annotationAdd
BLAST
Domaini3500 – 353233EGF-like 8PROSITE-ProRule annotationAdd
BLAST
Domaini3533 – 356432EGF-like 9PROSITE-ProRule annotationAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni887 – 8948O-glycosylated at one site

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi2845 – 28473Cell attachment siteSequence Analysis

Sequence similaritiesi

Contains 9 EGF-like domains.PROSITE-ProRule annotation
Contains 2 HYR domains.PROSITE-ProRule annotation
Contains 1 pentaxin domain.Curated
Contains 34 Sushi (CCP/SCR) domains.PROSITE-ProRule annotation
Contains 1 VWFA domain.PROSITE-ProRule annotation

Keywords - Domaini

EGF-like domain, Repeat, Signal, Sushi

Phylogenomic databases

eggNOGiNOG12793.
GeneTreeiENSGT00760000118786.
HOVERGENiHBG108523.
InParanoidiQ4LDE5.
KOiK17495.
OMAiIDCRLED.
OrthoDBiEOG7BS48H.
PhylomeDBiQ4LDE5.
TreeFamiTF342247.

Family and domain databases

Gene3Di2.40.155.10. 1 hit.
2.60.120.200. 1 hit.
3.40.50.410. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR000742. EG-like_dom.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR023413. GFP_like.
IPR009030. Growth_fac_rcpt_N_dom.
IPR003410. Hyalin.
IPR001759. Pentaxin.
IPR000436. Sushi_SCR_CCP.
IPR011641. Tyr-kin_ephrin_A/B_rcpt-like.
IPR002035. VWF_A.
[Graphical view]
PfamiPF00008. EGF. 5 hits.
PF07645. EGF_CA. 1 hit.
PF07699. GCC2_GCC3. 4 hits.
PF12661. hEGF. 1 hit.
PF02494. HYR. 2 hits.
PF00354. Pentaxin. 1 hit.
PF00084. Sushi. 32 hits.
PF00092. VWA. 1 hit.
[Graphical view]
PRINTSiPR00895. PENTAXIN.
SMARTiSM00032. CCP. 34 hits.
SM00181. EGF. 4 hits.
SM00179. EGF_CA. 6 hits.
SM00327. VWA. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF53300. SSF53300. 1 hit.
SSF57184. SSF57184. 3 hits.
SSF57535. SSF57535. 33 hits.
PROSITEiPS00010. ASX_HYDROXYL. 6 hits.
PS00022. EGF_1. 9 hits.
PS01186. EGF_2. 11 hits.
PS50026. EGF_3. 9 hits.
PS01187. EGF_CA. 6 hits.
PS50825. HYR. 2 hits.
PS50923. SUSHI. 34 hits.
PS50234. VWFA. 1 hit.
[Graphical view]

Sequences (4)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 4 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q4LDE5-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MWPRLAFCCW GLALVSGWAT FQQMSPSRNF SFRLFPETAP GAPGSIPAPP
60 70 80 90 100
APGDEAAGSR VERLGQAFRR RVRLLRELSE RLELVFLVDD SSSVGEVNFR
110 120 130 140 150
SELMFVRKLL SDFPVVPTAT RVAIVTFSSK NYVVPRVDYI STRRARQHKC
160 170 180 190 200
ALLLQEIPAI SYRGGGTYTK GAFQQAAQIL LHARENSTKV VFLITDGYSN
210 220 230 240 250
GGDPRPIAAS LRDSGVEIFT FGIWQGNIRE LNDMASTPKE EHCYLLHSFE
260 270 280 290 300
EFEALARRAL HEDLPSGSFI QDDMVHCSYL CDEGKDCCDR MGSCKCGTHT
310 320 330 340 350
GHFECICEKG YYGKGLQYEC TACPSGTYKP EGSPGGISSC IPCPDENHTS
360 370 380 390 400
PPGSTSPEDC VCREGYRASG QTCELVHCPA LKPPENGYFI QNTCNNHFNA
410 420 430 440 450
ACGVRCHPGF DLVGSSIILC LPNGLWSGSE SYCRVRTCPH LRQPKHGHIS
460 470 480 490 500
CSTREMLYKT TCLVACDEGY RLEGSDKLTC QGNSQWDGPE PRCVERHCST
510 520 530 540 550
FQMPKDVIIS PHNCGKQPAK FGTICYVSCR QGFILSGVKE MLRCTTSGKW
560 570 580 590 600
NVGVQAAVCK DVEAPQINCP KDIEAKTLEQ QDSANVTWQI PTAKDNSGEK
610 620 630 640 650
VSVHVHPAFT PPYLFPIGDV AIVYTATDLS GNQASCIFHI KVIDAEPPVI
660 670 680 690 700
DWCRSPPPVQ VSEKVHAASW DEPQFSDNSG AELVITRSHT QGDLFPQGET
710 720 730 740 750
IVQYTATDPS GNNRTCDIHI VIKGSPCEIP FTPVNGDFIC TPDNTGVNCT
760 770 780 790 800
LTCLEGYDFT EGSTDKYYCA YEDGVWKPTY TTEWPDCAKK RFANHGFKSF
810 820 830 840 850
EMFYKAARCD DTDLMKKFSE AFETTLGKMV PSFCSDAEDI DCRLEENLTK
860 870 880 890 900
KYCLEYNYDY ENGFAIGPGG WGAANRLDYS YDDFLDTVQE TATSIGNAKS
910 920 930 940 950
SRIKRSAPLS DYKIKLIFNI TASVPLPDER NDTLEWENQQ RLLQTLETIT
960 970 980 990 1000
NKLKRTLNKD PMYSFQLASE ILIADSNSLE TKKASPFCRP GSVLRGRMCV
1010 1020 1030 1040 1050
NCPLGTYYNL EHFTCESCRI GSYQDEEGQL ECKLCPSGMY TEYIHSRNIS
1060 1070 1080 1090 1100
DCKAQCKQGT YSYSGLETCE SCPLGTYQPK FGSRSCLSCP ENTSTVKRGA
1110 1120 1130 1140 1150
VNISACGVPC PEGKFSRSGL MPCHPCPRDY YQPNAGKAFC LACPFYGTTP
1160 1170 1180 1190 1200
FAGSRSITEC SSFSSTFSAA EESVVPPASL GHIKKRHEIS SQVFHECFFN
1210 1220 1230 1240 1250
PCHNSGTCQQ LGRGYVCLCP LGYTGLKCET DIDECSPLPC LNNGVCKDLV
1260 1270 1280 1290 1300
GEFICECPSG YTGQRCEENI NECSSSPCLN KGICVDGVAG YRCTCVKGFV
1310 1320 1330 1340 1350
GLHCETEVNE CQSNPCLNNA VCEDQVGGFL CKCPPGFLGT RCGKNVDECL
1360 1370 1380 1390 1400
SQPCKNGATC KDGANSFRCL CAAGFTGSHC ELNINECQSN PCRNQATCVD
1410 1420 1430 1440 1450
ELNSYSCKCQ PGFSGKRCET EQSTGFNLDF EVSGIYGYVM LDGMLPSLHA
1460 1470 1480 1490 1500
LTCTFWMKSS DDMNYGTPIS YAVDNGSDNT LLLTDYNGWV LYVNGREKIT
1510 1520 1530 1540 1550
NCPSVNDGRW HHIAITWTSA NGIWKVYIDG KLSDGGAGLS VGLPIPGGGA
1560 1570 1580 1590 1600
LVLGQEQDKK GEGFSPAESF VGSISQLNLW DYVLSPQQVK SLATSCPEEL
1610 1620 1630 1640 1650
SKGNVLAWPD FLSGIVGKVK IDSKSIFCSD CPRLGGSVPH LRTASEDLKP
1660 1670 1680 1690 1700
GSKVNLFCDP GFQLVGNPVQ YCLNQGQWTQ PLPHCERISC GVPPPLENGF
1710 1720 1730 1740 1750
HSADDFYAGS TVTYQCNNGY YLLGDSRMFC TDNGSWNGVS PSCLDVDECA
1760 1770 1780 1790 1800
VGSDCSEHAS CLNVDGSYIC SCVPPYTGDG KNCAEPIKCK APGNPENGHS
1810 1820 1830 1840 1850
SGEIYTVGAE VTFSCQEGYQ LMGVTKITCL ESGEWNHLIP YCKAVSCGKP
1860 1870 1880 1890 1900
AIPENGCIEE LAFTFGSKVT YRCNKGYTLA GDKESSCLAN SSWSHSPPVC
1910 1920 1930 1940 1950
EPVKCSSPEN INNGKYILSG LTYLSTASYS CDTGYSLQGP SIIECTASGI
1960 1970 1980 1990 2000
WDRAPPACHL VFCGEPPAIK DAVITGNNFT FRNTVTYTCK EGYTLAGLDT
2010 2020 2030 2040 2050
IECLADGKWS RSDQQCLAVS CDEPPIVDHA SPETAHRLFG DIAFYYCSDG
2060 2070 2080 2090 2100
YSLADNSQLL CNAQGKWVPP EGQDMPRCIA HFCEKPPSVS YSILESVSKA
2110 2120 2130 2140 2150
KFAAGSVVSF KCMEGFVLNT SAKIECMRGG QWNPSPMSIQ CIPVRCGEPP
2160 2170 2180 2190 2200
SIMNGYASGS NYSFGAMVAY SCNKGFYIKG EKKSTCEATG QWSSPIPTCH
2210 2220 2230 2240 2250
PVSCGEPPKV ENGFLEHTTG RIFESEVRYQ CNPGYKSVGS PVFVCQANRH
2260 2270 2280 2290 2300
WHSESPLMCV PLDCGKPPPI QNGFMKGENF EVGSKVQFFC NEGYELVGDS
2310 2320 2330 2340 2350
SWTCQKSGKW NKKSNPKCMP AKCPEPPLLE NQLVLKELTT EVGVVTFSCK
2360 2370 2380 2390 2400
EGHVLQGPSV LKCLPSQQWN DSFPVCKIVL CTPPPLISFG VPIPSSALHF
2410 2420 2430 2440 2450
GSTVKYSCVG GFFLRGNSTT LCQPDGTWSS PLPECVPVEC PQPEEIPNGI
2460 2470 2480 2490 2500
IDVQGLAYLS TALYTCKPGF ELVGNTTTLC GENGHWLGGK PTCKAIECLK
2510 2520 2530 2540 2550
PKEILNGKFS YTDLHYGQTV TYSCNRGFRL EGPSALTCLE TGDWDVDAPS
2560 2570 2580 2590 2600
CNAIHCDSPQ PIENGFVEGA DYSYGAIIIY SCFPGFQVAG HAMQTCEESG
2610 2620 2630 2640 2650
WSSSIPTCMP IDCGLPPHID FGDCTKLKDD QGYFEQEDDM MEVPYVTPHP
2660 2670 2680 2690 2700
PYHLGAVAKT WENTKESPAT HSSNFLYGTM VSYTCNPGYE LLGNPVLICQ
2710 2720 2730 2740 2750
EDGTWNGSAP SCISIECDLP TAPENGFLRF TETSMGSAVQ YSCKPGHILA
2760 2770 2780 2790 2800
GSDLRLCLEN RKWSGASPRC EAISCKKPNP VMNGSIKGSN YTYLSTLYYE
2810 2820 2830 2840 2850
CDPGYVLNGT ERRTCQDDKN WDEDEPICIP VDCSSPPVSA NGQVRGDEYT
2860 2870 2880 2890 2900
FQKEIEYTCN EGFLLEGARS RVCLANGSWS GATPDCVPVR CATPPQLANG
2910 2920 2930 2940 2950
VTEGLDYGFM KEVTFHCHEG YILHGAPKLT CQSDGNWDAE IPLCKPVNCG
2960 2970 2980 2990 3000
PPEDLAHGFP NGFSFIHGGH IQYQCFPGYK LHGNSSRRCL SNGSWSGSSP
3010 3020 3030 3040 3050
SCLPCRCSTP VIEYGTVNGT DFDCGKAARI QCFKGFKLLG LSEITCEADG
3060 3070 3080 3090 3100
QWSSGFPHCE HTSCGSLPMI PNAFISETSS WKENVITYSC RSGYVIQGSS
3110 3120 3130 3140 3150
DLICTEKGVW SQPYPVCEPL SCGSPPSVAN AVATGEAHTY ESEVKLRCLE
3160 3170 3180 3190 3200
GYTMDTDTDT FTCQKDGRWF PERISCSPKK CPLPENITHI LVHGDDFSVN
3210 3220 3230 3240 3250
RQVSVSCAEG YTFEGVNISV CQLDGTWEPP FSDESCSPVS CGKPESPEHG
3260 3270 3280 3290 3300
FVVGSKYTFE STIIYQCEPG YELEGNRERV CQENRQWSGG VAICKETRCE
3310 3320 3330 3340 3350
TPLEFLNGKA DIENRTTGPN VVYSCNRGYS LEGPSEAHCT ENGTWSHPVP
3360 3370 3380 3390 3400
LCKPNPCPVP FVIPENALLS EKEFYVDQNV SIKCREGFLL QGHGIITCNP
3410 3420 3430 3440 3450
DETWTQTSAK CEKISCGPPA HVENAIARGV HYQYGDMITY SCYSGYMLEG
3460 3470 3480 3490 3500
FLRSVCLENG TWTSPPICRA VCRFPCQNGG ICQRPNACSC PEGWMGRLCE
3510 3520 3530 3540 3550
EPICILPCLN GGRCVAPYQC DCPPGWTGSR CHTAVCQSPC LNGGKCVRPN
3560 3570
RCHCLSSWTG HNCSRKRRTG F
Length:3,571
Mass (Da):390,170
Last modified:May 18, 2010 - v3
Checksum:i8F52DE456CED5DED
GO
Isoform 2 (identifier: Q4LDE5-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     868-868: P → N
     869-3571: Missing.

Show »
Length:868
Mass (Da):96,134
Checksum:i516974CD450855FD
GO
Isoform 3 (identifier: Q4LDE5-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-2074: Missing.

Show »
Length:1,497
Mass (Da):163,559
Checksum:i98D8650DB3B69DD4
GO
Isoform 4 (identifier: Q4LDE5-4) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1547-3571: Missing.

Note: No experimental confirmation available.

Show »
Length:1,546
Mass (Da):170,093
Checksum:iB304C96189C62CD1
GO

Sequence cautioni

The sequence AAG48257.1 differs from that shown. Reason: Frameshift at positions 2630, 2638 and 2655.
The sequence AAG48257.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
The sequence BAB14617.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
The sequence BAB55420.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
The sequence CAH73557.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
The sequence CAH74138.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
The sequence CAH73558.1 differs from that shown. Reason: Erroneous gene model prediction.
The sequence CAH74139.1 differs from that shown. Reason: Erroneous gene model prediction.
The sequence CAI14068.1 differs from that shown. Reason: Erroneous gene model prediction.

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti429 – 4291S → L in CAF04067. (PubMed:16206243)Curated
Sequence conflicti429 – 4291S → L in BAB55420. (PubMed:14702039)Curated
Sequence conflicti604 – 6041H → R in BAB14617. (PubMed:14702039)Curated
Sequence conflicti822 – 8221F → L in BAB14617. (PubMed:14702039)Curated
Sequence conflicti842 – 8421C → W in CAF04067. (PubMed:16206243)Curated
Sequence conflicti842 – 8421C → W in BAB55420. (PubMed:14702039)Curated
Sequence conflicti980 – 9801E → G in CAF04067. (PubMed:16206243)Curated
Sequence conflicti980 – 9801E → G in BAB55420. (PubMed:14702039)Curated
Sequence conflicti1063 – 10631Y → C in CAF04067. (PubMed:16206243)Curated
Sequence conflicti1063 – 10631Y → C in BAB55420. (PubMed:14702039)Curated
Sequence conflicti1442 – 14421D → V in CAF04067. (PubMed:16206243)Curated
Sequence conflicti1442 – 14421D → V in BAB55420. (PubMed:14702039)Curated
Sequence conflicti1546 – 15461P → PGMF in CAF04067. (PubMed:16206243)Curated
Sequence conflicti1775 – 17751P → S in CAF04067. (PubMed:16206243)Curated
Sequence conflicti2179 – 21791K → E in CAD97901. (PubMed:17974005)Curated
Sequence conflicti2189 – 21891T → S in BAC11489. (PubMed:14702039)Curated
Sequence conflicti2237 – 22371S → P in BAC11489. (PubMed:14702039)Curated
Sequence conflicti2246 – 22461Q → H in BAC11489. (PubMed:14702039)Curated
Sequence conflicti2259 – 22591C → W in BAC11489. (PubMed:14702039)Curated
Sequence conflicti2299 – 22991D → G in CAD97988. (PubMed:17974005)Curated
Sequence conflicti2454 – 24541Q → R in BAC11489. (PubMed:14702039)Curated
Sequence conflicti2519 – 25191T → I in CAD97901. (PubMed:17974005)Curated
Sequence conflicti2623 – 26231D → A in AAG48257. (PubMed:12747765)Curated
Sequence conflicti2705 – 27051W → R in BAC11489. (PubMed:14702039)Curated
Sequence conflicti2753 – 27531D → G in BAC11489. (PubMed:14702039)Curated
Sequence conflicti2833 – 28331C → R in BAC11489. (PubMed:14702039)Curated
Sequence conflicti2857 – 28571Y → H in CAD97901. (PubMed:17974005)Curated
Sequence conflicti3005 – 30051C → F in BAC11489. (PubMed:14702039)Curated
Sequence conflicti3186 – 31861N → S in CAD97988. (PubMed:17974005)Curated
Sequence conflicti3302 – 33021P → Q in CAF04067. (PubMed:16206243)Curated
Sequence conflicti3302 – 33021P → Q in BAC11489. (PubMed:14702039)Curated
Sequence conflicti3398 – 33981C → Y in CAF04067. (PubMed:16206243)Curated
Sequence conflicti3398 – 33981C → Y in BAC11489. (PubMed:14702039)Curated
Sequence conflicti3565 – 35651R → G in CAD97988. (PubMed:17974005)Curated
Sequence conflicti3567 – 35671R → G in CAD97988. (PubMed:17974005)Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti332 – 3321G → A.1 Publication
Corresponds to variant rs3818764 [ dbSNP | Ensembl ].
VAR_039153
Natural varianti428 – 4281G → S.
Corresponds to variant rs10980419 [ dbSNP | Ensembl ].
VAR_039154
Natural varianti507 – 5071V → I.
Corresponds to variant rs872665 [ dbSNP | Ensembl ].
VAR_039155
Natural varianti581 – 5811Q → H.
Corresponds to variant rs10817033 [ dbSNP | Ensembl ].
VAR_039156
Natural varianti637 – 6371I → V.
Corresponds to variant rs13286541 [ dbSNP | Ensembl ].
VAR_039157
Natural varianti899 – 8991K → R.
Corresponds to variant rs10817025 [ dbSNP | Ensembl ].
VAR_039158
Natural varianti1157 – 11571I → V.
Corresponds to variant rs7038903 [ dbSNP | Ensembl ].
VAR_039159
Natural varianti1330 – 13301L → M.
Corresponds to variant rs10817021 [ dbSNP | Ensembl ].
VAR_039160
Natural varianti1416 – 14161K → Q.
Corresponds to variant rs1889323 [ dbSNP | Ensembl ].
VAR_039161
Natural varianti1444 – 14441M → L.
Corresponds to variant rs7863519 [ dbSNP | Ensembl ].
VAR_039162
Natural varianti1648 – 16481L → V.
Corresponds to variant rs7852962 [ dbSNP | Ensembl ].
VAR_039163
Natural varianti1810 – 18101E → A.
Corresponds to variant rs2986671 [ dbSNP | Ensembl ].
VAR_039164
Natural varianti1953 – 19531R → K.
Corresponds to variant rs17204832 [ dbSNP | Ensembl ].
VAR_039165
Natural varianti2607 – 26071T → A.
Corresponds to variant rs3802433 [ dbSNP | Ensembl ].
VAR_039166
Natural varianti2750 – 27501A → V.1 Publication
Corresponds to variant rs7030192 [ dbSNP | Ensembl ].
VAR_039167
Natural varianti2922 – 29221I → V.
Corresponds to variant rs16914996 [ dbSNP | Ensembl ].
VAR_039168
Natural varianti3161 – 31611F → I.1 Publication
Corresponds to variant rs3739451 [ dbSNP | Ensembl ].
VAR_039169
Natural varianti3230 – 32301P → T.
Corresponds to variant rs16914992 [ dbSNP | Ensembl ].
VAR_039170
Natural varianti3559 – 35591T → M.
Corresponds to variant rs17204533 [ dbSNP | Ensembl ].
VAR_039171

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 20742074Missing in isoform 3. 2 PublicationsVSP_031625Add
BLAST
Alternative sequencei868 – 8681P → N in isoform 2. 2 PublicationsVSP_031626
Alternative sequencei869 – 35712703Missing in isoform 2. 2 PublicationsVSP_031627Add
BLAST
Alternative sequencei1547 – 35712025Missing in isoform 4. 1 PublicationVSP_031628Add
BLAST

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ619977 mRNA. Translation: CAF04067.1.
AY916667 mRNA. Translation: AAX12481.1.
AK023591 mRNA. Translation: BAB14617.1. Different initiation.
AK075235 mRNA. Translation: BAC11489.1.
AK027870 mRNA. Translation: BAB55420.1. Different initiation.
AL158158 Genomic DNA. Translation: CAI14071.1.
AL592463, AL354982 Genomic DNA. Translation: CAH73557.1. Different initiation.
AL592463, AL158158, AL354982 Genomic DNA. Translation: CAH73558.1. Sequence problems.
AL354982, AL592463 Genomic DNA. Translation: CAH74138.1. Different initiation.
AL354982, AL158158, AL592463 Genomic DNA. Translation: CAH74139.1. Sequence problems.
AL158158, AL354982, AL592463 Genomic DNA. Translation: CAI14068.1. Sequence problems.
BC030816 mRNA. Translation: AAH30816.1.
BX537918 mRNA. Translation: CAD97901.1.
BX538049 mRNA. Translation: CAD97988.1.
AF308289 mRNA. Translation: AAG48257.1. Sequence problems.
RefSeqiNP_699197.3. NM_153366.3. [Q4LDE5-1]
UniGeneiHs.522334.
Hs.726867.

Genome annotation databases

EnsembliENST00000297826; ENSP00000297826; ENSG00000165124. [Q4LDE5-3]
GeneIDi79987.
KEGGihsa:79987.
UCSCiuc004beu.2. human. [Q4LDE5-2]
uc010mty.3. human. [Q4LDE5-3]
uc010mtz.3. human. [Q4LDE5-1]
uc010mua.1. human. [Q4LDE5-4]

Polymorphism databases

DMDMi296452942.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ619977 mRNA. Translation: CAF04067.1 .
AY916667 mRNA. Translation: AAX12481.1 .
AK023591 mRNA. Translation: BAB14617.1 . Different initiation.
AK075235 mRNA. Translation: BAC11489.1 .
AK027870 mRNA. Translation: BAB55420.1 . Different initiation.
AL158158 Genomic DNA. Translation: CAI14071.1 .
AL592463 , AL354982 Genomic DNA. Translation: CAH73557.1 . Different initiation.
AL592463 , AL158158 , AL354982 Genomic DNA. Translation: CAH73558.1 . Sequence problems.
AL354982 , AL592463 Genomic DNA. Translation: CAH74138.1 . Different initiation.
AL354982 , AL158158 , AL592463 Genomic DNA. Translation: CAH74139.1 . Sequence problems.
AL158158 , AL354982 , AL592463 Genomic DNA. Translation: CAI14068.1 . Sequence problems.
BC030816 mRNA. Translation: AAH30816.1 .
BX537918 mRNA. Translation: CAD97901.1 .
BX538049 mRNA. Translation: CAD97988.1 .
AF308289 mRNA. Translation: AAG48257.1 . Sequence problems.
RefSeqi NP_699197.3. NM_153366.3. [Q4LDE5-1 ]
UniGenei Hs.522334.
Hs.726867.

3D structure databases

ProteinModelPortali Q4LDE5.
SMRi Q4LDE5. Positions 79-255, 281-507, 1195-1422, 1445-3563.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 123051. 4 interactions.
IntActi Q4LDE5. 12 interactions.
MINTi MINT-1197821.

PTM databases

PhosphoSitei Q4LDE5.

Polymorphism databases

DMDMi 296452942.

Proteomic databases

MaxQBi Q4LDE5.
PaxDbi Q4LDE5.
PRIDEi Q4LDE5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000297826 ; ENSP00000297826 ; ENSG00000165124 . [Q4LDE5-3 ]
GeneIDi 79987.
KEGGi hsa:79987.
UCSCi uc004beu.2. human. [Q4LDE5-2 ]
uc010mty.3. human. [Q4LDE5-3 ]
uc010mtz.3. human. [Q4LDE5-1 ]
uc010mua.1. human. [Q4LDE5-4 ]

Organism-specific databases

CTDi 79987.
GeneCardsi GC09M113127.
H-InvDB HIX0008277.
HIX0035094.
HGNCi HGNC:15985. SVEP1.
HPAi HPA020610.
HPA021520.
MIMi 611691. gene.
neXtProti NX_Q4LDE5.
PharmGKBi PA25971.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG12793.
GeneTreei ENSGT00760000118786.
HOVERGENi HBG108523.
InParanoidi Q4LDE5.
KOi K17495.
OMAi IDCRLED.
OrthoDBi EOG7BS48H.
PhylomeDBi Q4LDE5.
TreeFami TF342247.

Miscellaneous databases

GenomeRNAii 79987.
NextBioi 70034.
PROi Q4LDE5.
SOURCEi Search...

Gene expression databases

Bgeei Q4LDE5.
Genevestigatori Q4LDE5.

Family and domain databases

Gene3Di 2.40.155.10. 1 hit.
2.60.120.200. 1 hit.
3.40.50.410. 1 hit.
InterProi IPR013320. ConA-like_dom.
IPR000742. EG-like_dom.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR023413. GFP_like.
IPR009030. Growth_fac_rcpt_N_dom.
IPR003410. Hyalin.
IPR001759. Pentaxin.
IPR000436. Sushi_SCR_CCP.
IPR011641. Tyr-kin_ephrin_A/B_rcpt-like.
IPR002035. VWF_A.
[Graphical view ]
Pfami PF00008. EGF. 5 hits.
PF07645. EGF_CA. 1 hit.
PF07699. GCC2_GCC3. 4 hits.
PF12661. hEGF. 1 hit.
PF02494. HYR. 2 hits.
PF00354. Pentaxin. 1 hit.
PF00084. Sushi. 32 hits.
PF00092. VWA. 1 hit.
[Graphical view ]
PRINTSi PR00895. PENTAXIN.
SMARTi SM00032. CCP. 34 hits.
SM00181. EGF. 4 hits.
SM00179. EGF_CA. 6 hits.
SM00327. VWA. 1 hit.
[Graphical view ]
SUPFAMi SSF49899. SSF49899. 1 hit.
SSF53300. SSF53300. 1 hit.
SSF57184. SSF57184. 3 hits.
SSF57535. SSF57535. 33 hits.
PROSITEi PS00010. ASX_HYDROXYL. 6 hits.
PS00022. EGF_1. 9 hits.
PS01186. EGF_2. 11 hits.
PS50026. EGF_3. 9 hits.
PS01187. EGF_CA. 6 hits.
PS50825. HYR. 2 hits.
PS50923. SUSHI. 34 hits.
PS50234. VWFA. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Molecular and cellular characterization of SEL-OB/SVEP1 in osteogenic cells in vivo and in vitro."
    Shur I., Socher R., Hameiri M., Fried A., Benayahu D.
    J. Cell. Physiol. 206:420-427(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
  2. Han J., Fang Y., Yan J., Ye Q.
    Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3).
    Tissue: Mammary gland.
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 195-3571 (ISOFORM 4), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 318-868 (ISOFORM 2), VARIANTS ALA-332 AND VAL-2750.
    Tissue: Placenta.
  4. "DNA sequence and analysis of human chromosome 9."
    Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L.
    , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I.
    Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Tissue: Placenta.
  6. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 2131-3571, VARIANT ILE-3161.
    Tissue: Colon endothelium.
  7. "Humoral immunity to human breast cancer: antigen definition and quantitative analysis of mRNA expression."
    Scanlan M.J., Gout I., Gordon C.M., Williamson B., Stockert E., Gure A.O., Jaeger D., Chen Y.-T., Mackay A., O'Hare M.J., Old L.J.
    Cancer Immun. 1:4-4(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 2269-2756.
    Tissue: Mammary gland.
  8. "Polydom: a secreted protein with pentraxin, complement control protein, epidermal growth factor and von Willebrand factor A domains."
    Gilges D., Vinit M.-A., Callebaut I., Coulombel L., Cacheux V., Romeo P.-H., Vigon I.
    Biochem. J. 352:49-59(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: TISSUE SPECIFICITY.
  9. "Human urinary glycoproteomics; attachment site specific analysis of N-and O-linked glycosylations by CID and ECD."
    Halim A., Nilsson J., Ruetschi U., Hesse C., Larson G.
    Mol. Cell. Proteomics 0:0-0(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: GLYCOSYLATION, STRUCTURE OF CARBOHYDRATES, IDENTIFICATION BY MASS SPECTROMETRY.

Entry informationi

Entry nameiSVEP1_HUMAN
AccessioniPrimary (citable) accession number: Q4LDE5
Secondary accession number(s): Q0P675
, Q5D213, Q5T938, Q5VTE4, Q5VTE5, Q7Z387, Q7Z3G3, Q8NBT9, Q96JU7, Q9H284, Q9H8J9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: May 18, 2010
Last modified: October 29, 2014
This is version 95 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3