Q4LDE5 (SVEP1_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1

Alternative name(s):
CCP module-containing protein 22
Polydom
Selectin-like osteoblast-derived protein
Short name=SEL-OB
Serologically defined breast cancer antigen NY-BR-38

Gene names

Name:	SVEP1
Synonyms:	C9orf13, CCP22, SELOB

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	3571 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	May play a role in the cell attachment process By similarity.
Subcellular location	Secreted Potential. Cytoplasm. Membrane; Peripheral membrane protein Ref.1.
Tissue specificity	Present in mesenchymal primary cultured cell lysates (at protein level). Highly expressed in placenta. Also expressed in marrow stromal cell. Weakly or not expressed in other tissues. Ref.1 Ref.8
Post-translational modification	O-glycosylated with core 1 or possibly core 8 glycans. Ref.9
Sequence similarities	Contains 9 EGF-like domains. Contains 2 HYR domains. Contains 1 pentaxin domain. Contains 34 Sushi (CCP/SCR) domains. Contains 1 VWFA domain.
Sequence caution	The sequence AAG48257.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended. The sequence AAG48257.1 differs from that shown. Reason: Frameshift at positions 2630, 2638 and 2655. The sequence BAB14617.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended. The sequence BAB55420.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended. The sequence CAH73557.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended. The sequence CAH73558.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence CAH74138.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended. The sequence CAH74139.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence CAI14068.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
Biological process	Cell adhesion
Cellular component	Cytoplasm Membrane Secreted
Coding sequence diversity	Alternative splicing Polymorphism
Domain	EGF-like domain Repeat Signal Sushi
Ligand	Calcium
PTM	Disulfide bond Glycoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cell adhesion Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	calcium ion binding Inferred from electronic annotation. Source: InterPro chromatin binding Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Alternative products

This entry describes 4 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q4LDE5-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q4LDE5-2)

The sequence of this isoform differs from the canonical sequence as follows:
     868-868: P → N
     869-3571: Missing.

Isoform 3 (identifier: Q4LDE5-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1-2074: Missing.

Isoform 4 (identifier: Q4LDE5-4)

The sequence of this isoform differs from the canonical sequence as follows:
     1547-3571: Missing.

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 17	17	Potential
	Chain	18 – 3571	3554	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1		PRO_0000320179
Regions
	Domain	83 – 264	182	VWFA
	Domain	376 – 435	60	Sushi 1
	Domain	436 – 495	60	Sushi 2
	Domain	496 – 561	66	Sushi 3
	Domain	560 – 642	83	HYR 1
	Domain	643 – 724	82	HYR 2
	Domain	725 – 789	65	Sushi 4
	Domain	1193 – 1229	37	EGF-like 1
	Domain	1231 – 1267	37	EGF-like 2; calcium-binding Potential
	Domain	1269 – 1305	37	EGF-like 3; calcium-binding Potential
	Domain	1307 – 1343	37	EGF-like 4; calcium-binding Potential
	Domain	1345 – 1381	37	EGF-like 5; calcium-binding Potential
	Domain	1383 – 1419	37	EGF-like 6; calcium-binding Potential
	Domain	1430 – 1623	194	Pentaxin
	Domain	1629 – 1687	59	Sushi 5
	Domain	1688 – 1745	58	Sushi 6
	Domain	1745 – 1784	40	EGF-like 7; calcium-binding Potential
	Domain	1787 – 1844	58	Sushi 7
	Domain	1845 – 1902	58	Sushi 8
	Domain	1903 – 1960	58	Sushi 9
	Domain	1961 – 2018	58	Sushi 10
	Domain	2019 – 2080	62	Sushi 11
	Domain	2081 – 2143	63	Sushi 12
	Domain	2144 – 2201	58	Sushi 13
	Domain	2202 – 2261	60	Sushi 14
	Domain	2262 – 2320	59	Sushi 15
	Domain	2321 – 2378	58	Sushi 16
	Domain	2379 – 2437	59	Sushi 17
	Domain	2438 – 2495	58	Sushi 18
	Domain	2496 – 2553	58	Sushi 19
	Domain	2554 – 2610	57	Sushi 20
	Domain	2663 – 2714	52	Sushi 21
	Domain	2715 – 2772	58	Sushi 22
	Domain	2773 – 2830	58	Sushi 23
	Domain	2831 – 2888	58	Sushi 24
	Domain	2889 – 2946	58	Sushi 25
	Domain	2947 – 3004	58	Sushi 26
	Domain	3005 – 3061	57	Sushi 27
	Domain	3062 – 3119	58	Sushi 28
	Domain	3120 – 3178	59	Sushi 29
	Domain	3179 – 3238	60	Sushi 30
	Domain	3239 – 3296	58	Sushi 31
	Domain	3297 – 3354	58	Sushi 32
	Domain	3355 – 3413	59	Sushi 33
	Domain	3414 – 3470	57	Sushi 34
	Domain	3500 – 3532	33	EGF-like 8
	Domain	3533 – 3564	32	EGF-like 9
	Region	887 – 894	8	O-glycosylated at one site
	Motif	2845 – 2847	3	Cell attachment site Potential
Amino acid modifications
	Glycosylation	186	1	N-linked (GlcNAc...) Potential
	Glycosylation	847	1	N-linked (GlcNAc...) Potential
	Glycosylation	1102	1	N-linked (GlcNAc...) Potential
	Glycosylation	3018	1	N-linked (GlcNAc...) Potential
	Glycosylation	3186	1	N-linked (GlcNAc...) Potential
	Disulfide bond	378 ↔ 420		By similarity
	Disulfide bond	406 ↔ 433		By similarity
	Disulfide bond	438 ↔ 480		By similarity
	Disulfide bond	466 ↔ 493		By similarity
	Disulfide bond	498 ↔ 544		By similarity
	Disulfide bond	529 ↔ 559		By similarity
	Disulfide bond	727 ↔ 769		By similarity
	Disulfide bond	753 ↔ 787		By similarity
	Disulfide bond	1197 ↔ 1208		By similarity
	Disulfide bond	1202 ↔ 1217		By similarity
	Disulfide bond	1219 ↔ 1228		By similarity
	Disulfide bond	1235 ↔ 1246		By similarity
	Disulfide bond	1240 ↔ 1255		By similarity
	Disulfide bond	1257 ↔ 1266		By similarity
	Disulfide bond	1273 ↔ 1284		By similarity
	Disulfide bond	1278 ↔ 1293		By similarity
	Disulfide bond	1295 ↔ 1304		By similarity
	Disulfide bond	1311 ↔ 1322		By similarity
	Disulfide bond	1316 ↔ 1331		By similarity
	Disulfide bond	1333 ↔ 1342		By similarity
	Disulfide bond	1349 ↔ 1360		By similarity
	Disulfide bond	1354 ↔ 1369		By similarity
	Disulfide bond	1371 ↔ 1380		By similarity
	Disulfide bond	1387 ↔ 1398		By similarity
	Disulfide bond	1392 ↔ 1407		By similarity
	Disulfide bond	1409 ↔ 1418		By similarity
	Disulfide bond	1631 ↔ 1672		By similarity
	Disulfide bond	1658 ↔ 1685		By similarity
	Disulfide bond	1690 ↔ 1730		By similarity
	Disulfide bond	1716 ↔ 1743		By similarity
	Disulfide bond	1749 ↔ 1761		By similarity
	Disulfide bond	1755 ↔ 1770		By similarity
	Disulfide bond	1772 ↔ 1783		By similarity
	Disulfide bond	1789 ↔ 1829		By similarity
	Disulfide bond	1815 ↔ 1842		By similarity
	Disulfide bond	1847 ↔ 1887		By similarity
	Disulfide bond	1873 ↔ 1900		By similarity
	Disulfide bond	1905 ↔ 1945		By similarity
	Disulfide bond	1931 ↔ 1958		By similarity
	Disulfide bond	1963 ↔ 2003		By similarity
	Disulfide bond	1989 ↔ 2016		By similarity
	Disulfide bond	2021 ↔ 2061		By similarity
	Disulfide bond	2047 ↔ 2078		By similarity
	Disulfide bond	2083 ↔ 2126		By similarity
	Disulfide bond	2112 ↔ 2141		By similarity
	Disulfide bond	2146 ↔ 2186		By similarity
	Disulfide bond	2172 ↔ 2199		By similarity
	Disulfide bond	2204 ↔ 2245		By similarity
	Disulfide bond	2231 ↔ 2259		By similarity
	Disulfide bond	2264 ↔ 2304		By similarity
	Disulfide bond	2290 ↔ 2318		By similarity
	Disulfide bond	2323 ↔ 2363		By similarity
	Disulfide bond	2349 ↔ 2376		By similarity
	Disulfide bond	2381 ↔ 2422		By similarity
	Disulfide bond	2408 ↔ 2435		By similarity
	Disulfide bond	2440 ↔ 2480		By similarity
	Disulfide bond	2466 ↔ 2493		By similarity
	Disulfide bond	2498 ↔ 2538		By similarity
	Disulfide bond	2524 ↔ 2551		By similarity
	Disulfide bond	2556 ↔ 2596		By similarity
	Disulfide bond	2582 ↔ 2608		By similarity
	Disulfide bond	2685 ↔ 2712		By similarity
	Disulfide bond	2717 ↔ 2757		By similarity
	Disulfide bond	2743 ↔ 2770		By similarity
	Disulfide bond	2775 ↔ 2815		By similarity
	Disulfide bond	2801 ↔ 2828		By similarity
	Disulfide bond	2833 ↔ 2873		By similarity
	Disulfide bond	2859 ↔ 2886		By similarity
	Disulfide bond	2891 ↔ 2931		By similarity
	Disulfide bond	2917 ↔ 2944		By similarity
	Disulfide bond	2949 ↔ 2989		By similarity
	Disulfide bond	2975 ↔ 3002		By similarity
	Disulfide bond	3007 ↔ 3046		By similarity
	Disulfide bond	3032 ↔ 3059		By similarity
	Disulfide bond	3064 ↔ 3104		By similarity
	Disulfide bond	3090 ↔ 3117		By similarity
	Disulfide bond	3122 ↔ 3163		By similarity
	Disulfide bond	3148 ↔ 3176		By similarity
	Disulfide bond	3181 ↔ 3221		By similarity
	Disulfide bond	3207 ↔ 3236		By similarity
	Disulfide bond	3241 ↔ 3281		By similarity
	Disulfide bond	3267 ↔ 3294		By similarity
	Disulfide bond	3299 ↔ 3339		By similarity
	Disulfide bond	3325 ↔ 3352		By similarity
	Disulfide bond	3384 ↔ 3411		By similarity
	Disulfide bond	3416 ↔ 3456		By similarity
	Disulfide bond	3442 ↔ 3468		By similarity
	Disulfide bond	3504 ↔ 3514		By similarity
	Disulfide bond	3508 ↔ 3520		By similarity
	Disulfide bond	3522 ↔ 3531		By similarity
	Disulfide bond	3536 ↔ 3546		By similarity
	Disulfide bond	3540 ↔ 3552		By similarity
	Disulfide bond	3554 ↔ 3563		By similarity
Natural variations
	Alternative sequence	1 – 2074	2074	Missing in isoform 3.		VSP_031625
	Alternative sequence	868	1	P → N in isoform 2.		VSP_031626
	Alternative sequence	869 – 3571	2703	Missing in isoform 2.		VSP_031627
	Alternative sequence	1547 – 3571	2025	Missing in isoform 4.		VSP_031628
	Natural variant	332	1	G → A. Ref.3 Corresponds to variant rs3818764 [ dbSNP | Ensembl ].		VAR_039153
	Natural variant	428	1	G → S. Corresponds to variant rs10980419 [ dbSNP | Ensembl ].		VAR_039154
	Natural variant	507	1	V → I. Corresponds to variant rs872665 [ dbSNP | Ensembl ].		VAR_039155
	Natural variant	581	1	Q → H. Corresponds to variant rs10817033 [ dbSNP | Ensembl ].		VAR_039156
	Natural variant	637	1	I → V. Corresponds to variant rs13286541 [ dbSNP | Ensembl ].		VAR_039157
	Natural variant	899	1	K → R. Corresponds to variant rs10817025 [ dbSNP | Ensembl ].		VAR_039158
	Natural variant	1157	1	I → V. Corresponds to variant rs7038903 [ dbSNP | Ensembl ].		VAR_039159
	Natural variant	1330	1	L → M. Corresponds to variant rs10817021 [ dbSNP | Ensembl ].		VAR_039160
	Natural variant	1416	1	K → Q. Corresponds to variant rs1889323 [ dbSNP | Ensembl ].		VAR_039161
	Natural variant	1444	1	M → L. Corresponds to variant rs7863519 [ dbSNP | Ensembl ].		VAR_039162
	Natural variant	1648	1	L → V. Corresponds to variant rs7852962 [ dbSNP | Ensembl ].		VAR_039163
	Natural variant	1810	1	E → A. Corresponds to variant rs2986671 [ dbSNP | Ensembl ].		VAR_039164
	Natural variant	1953	1	R → K. Corresponds to variant rs17204832 [ dbSNP | Ensembl ].		VAR_039165
	Natural variant	2607	1	T → A. Corresponds to variant rs3802433 [ dbSNP | Ensembl ].		VAR_039166
	Natural variant	2750	1	A → V. Ref.3 Corresponds to variant rs7030192 [ dbSNP | Ensembl ].		VAR_039167
	Natural variant	2922	1	I → V. Corresponds to variant rs16914996 [ dbSNP | Ensembl ].		VAR_039168
	Natural variant	3161	1	F → I. Ref.6 Corresponds to variant rs3739451 [ dbSNP | Ensembl ].		VAR_039169
	Natural variant	3230	1	P → T. Corresponds to variant rs16914992 [ dbSNP | Ensembl ].		VAR_039170
	Natural variant	3559	1	T → M. Corresponds to variant rs17204533 [ dbSNP | Ensembl ].		VAR_039171
Experimental info
	Sequence conflict	429	1	S → L in CAF04067. Ref.1
	Sequence conflict	429	1	S → L in BAB55420. Ref.3
	Sequence conflict	604	1	H → R in BAB14617. Ref.3
	Sequence conflict	822	1	F → L in BAB14617. Ref.3
	Sequence conflict	842	1	C → W in CAF04067. Ref.1
	Sequence conflict	842	1	C → W in BAB55420. Ref.3
	Sequence conflict	980	1	E → G in CAF04067. Ref.1
	Sequence conflict	980	1	E → G in BAB55420. Ref.3
	Sequence conflict	1063	1	Y → C in CAF04067. Ref.1
	Sequence conflict	1063	1	Y → C in BAB55420. Ref.3
	Sequence conflict	1442	1	D → V in CAF04067. Ref.1
	Sequence conflict	1442	1	D → V in BAB55420. Ref.3
	Sequence conflict	1546	1	P → PGMF in CAF04067. Ref.1
	Sequence conflict	1775	1	P → S in CAF04067. Ref.1
	Sequence conflict	2179	1	K → E in CAD97901. Ref.6
	Sequence conflict	2189	1	T → S in BAC11489. Ref.3
	Sequence conflict	2237	1	S → P in BAC11489. Ref.3
	Sequence conflict	2246	1	Q → H in BAC11489. Ref.3
	Sequence conflict	2259	1	C → W in BAC11489. Ref.3
	Sequence conflict	2299	1	D → G in CAD97988. Ref.6
	Sequence conflict	2454	1	Q → R in BAC11489. Ref.3
	Sequence conflict	2519	1	T → I in CAD97901. Ref.6
	Sequence conflict	2623	1	D → A in AAG48257. Ref.7
	Sequence conflict	2705	1	W → R in BAC11489. Ref.3
	Sequence conflict	2753	1	D → G in BAC11489. Ref.3
	Sequence conflict	2833	1	C → R in BAC11489. Ref.3
	Sequence conflict	2857	1	Y → H in CAD97901. Ref.6
	Sequence conflict	3005	1	C → F in BAC11489. Ref.3
	Sequence conflict	3186	1	N → S in CAD97988. Ref.6
	Sequence conflict	3302	1	P → Q in CAF04067. Ref.1
	Sequence conflict	3302	1	P → Q in BAC11489. Ref.3
	Sequence conflict	3398	1	C → Y in CAF04067. Ref.1
	Sequence conflict	3398	1	C → Y in BAC11489. Ref.3
	Sequence conflict	3565	1	R → G in CAD97988. Ref.6
	Sequence conflict	3567	1	R → G in CAD97988. Ref.6

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified May 18, 2010. Version 3. Checksum: 8F52DE456CED5DED	FASTA	3,571	390,170
	10 20 30 40 50 60 MWPRLAFCCW GLALVSGWAT FQQMSPSRNF SFRLFPETAP GAPGSIPAPP APGDEAAGSR 70 80 90 100 110 120 VERLGQAFRR RVRLLRELSE RLELVFLVDD SSSVGEVNFR SELMFVRKLL SDFPVVPTAT 130 140 150 160 170 180 RVAIVTFSSK NYVVPRVDYI STRRARQHKC ALLLQEIPAI SYRGGGTYTK GAFQQAAQIL 190 200 210 220 230 240 LHARENSTKV VFLITDGYSN GGDPRPIAAS LRDSGVEIFT FGIWQGNIRE LNDMASTPKE 250 260 270 280 290 300 EHCYLLHSFE EFEALARRAL HEDLPSGSFI QDDMVHCSYL CDEGKDCCDR MGSCKCGTHT 310 320 330 340 350 360 GHFECICEKG YYGKGLQYEC TACPSGTYKP EGSPGGISSC IPCPDENHTS PPGSTSPEDC 370 380 390 400 410 420 VCREGYRASG QTCELVHCPA LKPPENGYFI QNTCNNHFNA ACGVRCHPGF DLVGSSIILC 430 440 450 460 470 480 LPNGLWSGSE SYCRVRTCPH LRQPKHGHIS CSTREMLYKT TCLVACDEGY RLEGSDKLTC 490 500 510 520 530 540 QGNSQWDGPE PRCVERHCST FQMPKDVIIS PHNCGKQPAK FGTICYVSCR QGFILSGVKE 550 560 570 580 590 600 MLRCTTSGKW NVGVQAAVCK DVEAPQINCP KDIEAKTLEQ QDSANVTWQI PTAKDNSGEK 610 620 630 640 650 660 VSVHVHPAFT PPYLFPIGDV AIVYTATDLS GNQASCIFHI KVIDAEPPVI DWCRSPPPVQ 670 680 690 700 710 720 VSEKVHAASW DEPQFSDNSG AELVITRSHT QGDLFPQGET IVQYTATDPS GNNRTCDIHI 730 740 750 760 770 780 VIKGSPCEIP FTPVNGDFIC TPDNTGVNCT LTCLEGYDFT EGSTDKYYCA YEDGVWKPTY 790 800 810 820 830 840 TTEWPDCAKK RFANHGFKSF EMFYKAARCD DTDLMKKFSE AFETTLGKMV PSFCSDAEDI 850 860 870 880 890 900 DCRLEENLTK KYCLEYNYDY ENGFAIGPGG WGAANRLDYS YDDFLDTVQE TATSIGNAKS 910 920 930 940 950 960 SRIKRSAPLS DYKIKLIFNI TASVPLPDER NDTLEWENQQ RLLQTLETIT NKLKRTLNKD 970 980 990 1000 1010 1020 PMYSFQLASE ILIADSNSLE TKKASPFCRP GSVLRGRMCV NCPLGTYYNL EHFTCESCRI 1030 1040 1050 1060 1070 1080 GSYQDEEGQL ECKLCPSGMY TEYIHSRNIS DCKAQCKQGT YSYSGLETCE SCPLGTYQPK 1090 1100 1110 1120 1130 1140 FGSRSCLSCP ENTSTVKRGA VNISACGVPC PEGKFSRSGL MPCHPCPRDY YQPNAGKAFC 1150 1160 1170 1180 1190 1200 LACPFYGTTP FAGSRSITEC SSFSSTFSAA EESVVPPASL GHIKKRHEIS SQVFHECFFN 1210 1220 1230 1240 1250 1260 PCHNSGTCQQ LGRGYVCLCP LGYTGLKCET DIDECSPLPC LNNGVCKDLV GEFICECPSG 1270 1280 1290 1300 1310 1320 YTGQRCEENI NECSSSPCLN KGICVDGVAG YRCTCVKGFV GLHCETEVNE CQSNPCLNNA 1330 1340 1350 1360 1370 1380 VCEDQVGGFL CKCPPGFLGT RCGKNVDECL SQPCKNGATC KDGANSFRCL CAAGFTGSHC 1390 1400 1410 1420 1430 1440 ELNINECQSN PCRNQATCVD ELNSYSCKCQ PGFSGKRCET EQSTGFNLDF EVSGIYGYVM 1450 1460 1470 1480 1490 1500 LDGMLPSLHA LTCTFWMKSS DDMNYGTPIS YAVDNGSDNT LLLTDYNGWV LYVNGREKIT 1510 1520 1530 1540 1550 1560 NCPSVNDGRW HHIAITWTSA NGIWKVYIDG KLSDGGAGLS VGLPIPGGGA LVLGQEQDKK 1570 1580 1590 1600 1610 1620 GEGFSPAESF VGSISQLNLW DYVLSPQQVK SLATSCPEEL SKGNVLAWPD FLSGIVGKVK 1630 1640 1650 1660 1670 1680 IDSKSIFCSD CPRLGGSVPH LRTASEDLKP GSKVNLFCDP GFQLVGNPVQ YCLNQGQWTQ 1690 1700 1710 1720 1730 1740 PLPHCERISC GVPPPLENGF HSADDFYAGS TVTYQCNNGY YLLGDSRMFC TDNGSWNGVS 1750 1760 1770 1780 1790 1800 PSCLDVDECA VGSDCSEHAS CLNVDGSYIC SCVPPYTGDG KNCAEPIKCK APGNPENGHS 1810 1820 1830 1840 1850 1860 SGEIYTVGAE VTFSCQEGYQ LMGVTKITCL ESGEWNHLIP YCKAVSCGKP AIPENGCIEE 1870 1880 1890 1900 1910 1920 LAFTFGSKVT YRCNKGYTLA GDKESSCLAN SSWSHSPPVC EPVKCSSPEN INNGKYILSG 1930 1940 1950 1960 1970 1980 LTYLSTASYS CDTGYSLQGP SIIECTASGI WDRAPPACHL VFCGEPPAIK DAVITGNNFT 1990 2000 2010 2020 2030 2040 FRNTVTYTCK EGYTLAGLDT IECLADGKWS RSDQQCLAVS CDEPPIVDHA SPETAHRLFG 2050 2060 2070 2080 2090 2100 DIAFYYCSDG YSLADNSQLL CNAQGKWVPP EGQDMPRCIA HFCEKPPSVS YSILESVSKA 2110 2120 2130 2140 2150 2160 KFAAGSVVSF KCMEGFVLNT SAKIECMRGG QWNPSPMSIQ CIPVRCGEPP SIMNGYASGS 2170 2180 2190 2200 2210 2220 NYSFGAMVAY SCNKGFYIKG EKKSTCEATG QWSSPIPTCH PVSCGEPPKV ENGFLEHTTG 2230 2240 2250 2260 2270 2280 RIFESEVRYQ CNPGYKSVGS PVFVCQANRH WHSESPLMCV PLDCGKPPPI QNGFMKGENF 2290 2300 2310 2320 2330 2340 EVGSKVQFFC NEGYELVGDS SWTCQKSGKW NKKSNPKCMP AKCPEPPLLE NQLVLKELTT 2350 2360 2370 2380 2390 2400 EVGVVTFSCK EGHVLQGPSV LKCLPSQQWN DSFPVCKIVL CTPPPLISFG VPIPSSALHF 2410 2420 2430 2440 2450 2460 GSTVKYSCVG GFFLRGNSTT LCQPDGTWSS PLPECVPVEC PQPEEIPNGI IDVQGLAYLS 2470 2480 2490 2500 2510 2520 TALYTCKPGF ELVGNTTTLC GENGHWLGGK PTCKAIECLK PKEILNGKFS YTDLHYGQTV 2530 2540 2550 2560 2570 2580 TYSCNRGFRL EGPSALTCLE TGDWDVDAPS CNAIHCDSPQ PIENGFVEGA DYSYGAIIIY 2590 2600 2610 2620 2630 2640 SCFPGFQVAG HAMQTCEESG WSSSIPTCMP IDCGLPPHID FGDCTKLKDD QGYFEQEDDM 2650 2660 2670 2680 2690 2700 MEVPYVTPHP PYHLGAVAKT WENTKESPAT HSSNFLYGTM VSYTCNPGYE LLGNPVLICQ 2710 2720 2730 2740 2750 2760 EDGTWNGSAP SCISIECDLP TAPENGFLRF TETSMGSAVQ YSCKPGHILA GSDLRLCLEN 2770 2780 2790 2800 2810 2820 RKWSGASPRC EAISCKKPNP VMNGSIKGSN YTYLSTLYYE CDPGYVLNGT ERRTCQDDKN 2830 2840 2850 2860 2870 2880 WDEDEPICIP VDCSSPPVSA NGQVRGDEYT FQKEIEYTCN EGFLLEGARS RVCLANGSWS 2890 2900 2910 2920 2930 2940 GATPDCVPVR CATPPQLANG VTEGLDYGFM KEVTFHCHEG YILHGAPKLT CQSDGNWDAE 2950 2960 2970 2980 2990 3000 IPLCKPVNCG PPEDLAHGFP NGFSFIHGGH IQYQCFPGYK LHGNSSRRCL SNGSWSGSSP 3010 3020 3030 3040 3050 3060 SCLPCRCSTP VIEYGTVNGT DFDCGKAARI QCFKGFKLLG LSEITCEADG QWSSGFPHCE 3070 3080 3090 3100 3110 3120 HTSCGSLPMI PNAFISETSS WKENVITYSC RSGYVIQGSS DLICTEKGVW SQPYPVCEPL 3130 3140 3150 3160 3170 3180 SCGSPPSVAN AVATGEAHTY ESEVKLRCLE GYTMDTDTDT FTCQKDGRWF PERISCSPKK 3190 3200 3210 3220 3230 3240 CPLPENITHI LVHGDDFSVN RQVSVSCAEG YTFEGVNISV CQLDGTWEPP FSDESCSPVS 3250 3260 3270 3280 3290 3300 CGKPESPEHG FVVGSKYTFE STIIYQCEPG YELEGNRERV CQENRQWSGG VAICKETRCE 3310 3320 3330 3340 3350 3360 TPLEFLNGKA DIENRTTGPN VVYSCNRGYS LEGPSEAHCT ENGTWSHPVP LCKPNPCPVP 3370 3380 3390 3400 3410 3420 FVIPENALLS EKEFYVDQNV SIKCREGFLL QGHGIITCNP DETWTQTSAK CEKISCGPPA 3430 3440 3450 3460 3470 3480 HVENAIARGV HYQYGDMITY SCYSGYMLEG FLRSVCLENG TWTSPPICRA VCRFPCQNGG 3490 3500 3510 3520 3530 3540 ICQRPNACSC PEGWMGRLCE EPICILPCLN GGRCVAPYQC DCPPGWTGSR CHTAVCQSPC 3550 3560 3570 LNGGKCVRPN RCHCLSSWTG HNCSRKRRTG F
	Isoform 2 [UniParc]. Checksum: 516974CD450855FD	FASTA	868	96,134
	10 20 30 40 50 60 MWPRLAFCCW GLALVSGWAT FQQMSPSRNF SFRLFPETAP GAPGSIPAPP APGDEAAGSR 70 80 90 100 110 120 VERLGQAFRR RVRLLRELSE RLELVFLVDD SSSVGEVNFR SELMFVRKLL SDFPVVPTAT 130 140 150 160 170 180 RVAIVTFSSK NYVVPRVDYI STRRARQHKC ALLLQEIPAI SYRGGGTYTK GAFQQAAQIL 190 200 210 220 230 240 LHARENSTKV VFLITDGYSN GGDPRPIAAS LRDSGVEIFT FGIWQGNIRE LNDMASTPKE 250 260 270 280 290 300 EHCYLLHSFE EFEALARRAL HEDLPSGSFI QDDMVHCSYL CDEGKDCCDR MGSCKCGTHT 310 320 330 340 350 360 GHFECICEKG YYGKGLQYEC TACPSGTYKP EGSPGGISSC IPCPDENHTS PPGSTSPEDC 370 380 390 400 410 420 VCREGYRASG QTCELVHCPA LKPPENGYFI QNTCNNHFNA ACGVRCHPGF DLVGSSIILC 430 440 450 460 470 480 LPNGLWSGSE SYCRVRTCPH LRQPKHGHIS CSTREMLYKT TCLVACDEGY RLEGSDKLTC 490 500 510 520 530 540 QGNSQWDGPE PRCVERHCST FQMPKDVIIS PHNCGKQPAK FGTICYVSCR QGFILSGVKE 550 560 570 580 590 600 MLRCTTSGKW NVGVQAAVCK DVEAPQINCP KDIEAKTLEQ QDSANVTWQI PTAKDNSGEK 610 620 630 640 650 660 VSVHVHPAFT PPYLFPIGDV AIVYTATDLS GNQASCIFHI KVIDAEPPVI DWCRSPPPVQ 670 680 690 700 710 720 VSEKVHAASW DEPQFSDNSG AELVITRSHT QGDLFPQGET IVQYTATDPS GNNRTCDIHI 730 740 750 760 770 780 VIKGSPCEIP FTPVNGDFIC TPDNTGVNCT LTCLEGYDFT EGSTDKYYCA YEDGVWKPTY 790 800 810 820 830 840 TTEWPDCAKK RFANHGFKSF EMFYKAARCD DTDLMKKFSE AFETTLGKMV PSFCSDAEDI 850 860 DCRLEENLTK KYCLEYNYDY ENGFAIGN
	Isoform 3 [UniParc]. Checksum: 98D8650DB3B69DD4	FASTA	1,497	163,559
	10 20 30 40 50 60 MPRCIAHFCE KPPSVSYSIL ESVSKAKFAA GSVVSFKCME GFVLNTSAKI ECMRGGQWNP 70 80 90 100 110 120 SPMSIQCIPV RCGEPPSIMN GYASGSNYSF GAMVAYSCNK GFYIKGEKKS TCEATGQWSS 130 140 150 160 170 180 PIPTCHPVSC GEPPKVENGF LEHTTGRIFE SEVRYQCNPG YKSVGSPVFV CQANRHWHSE 190 200 210 220 230 240 SPLMCVPLDC GKPPPIQNGF MKGENFEVGS KVQFFCNEGY ELVGDSSWTC QKSGKWNKKS 250 260 270 280 290 300 NPKCMPAKCP EPPLLENQLV LKELTTEVGV VTFSCKEGHV LQGPSVLKCL PSQQWNDSFP 310 320 330 340 350 360 VCKIVLCTPP PLISFGVPIP SSALHFGSTV KYSCVGGFFL RGNSTTLCQP DGTWSSPLPE 370 380 390 400 410 420 CVPVECPQPE EIPNGIIDVQ GLAYLSTALY TCKPGFELVG NTTTLCGENG HWLGGKPTCK 430 440 450 460 470 480 AIECLKPKEI LNGKFSYTDL HYGQTVTYSC NRGFRLEGPS ALTCLETGDW DVDAPSCNAI 490 500 510 520 530 540 HCDSPQPIEN GFVEGADYSY GAIIIYSCFP GFQVAGHAMQ TCEESGWSSS IPTCMPIDCG 550 560 570 580 590 600 LPPHIDFGDC TKLKDDQGYF EQEDDMMEVP YVTPHPPYHL GAVAKTWENT KESPATHSSN 610 620 630 640 650 660 FLYGTMVSYT CNPGYELLGN PVLICQEDGT WNGSAPSCIS IECDLPTAPE NGFLRFTETS 670 680 690 700 710 720 MGSAVQYSCK PGHILAGSDL RLCLENRKWS GASPRCEAIS CKKPNPVMNG SIKGSNYTYL 730 740 750 760 770 780 STLYYECDPG YVLNGTERRT CQDDKNWDED EPICIPVDCS SPPVSANGQV RGDEYTFQKE 790 800 810 820 830 840 IEYTCNEGFL LEGARSRVCL ANGSWSGATP DCVPVRCATP PQLANGVTEG LDYGFMKEVT 850 860 870 880 890 900 FHCHEGYILH GAPKLTCQSD GNWDAEIPLC KPVNCGPPED LAHGFPNGFS FIHGGHIQYQ 910 920 930 940 950 960 CFPGYKLHGN SSRRCLSNGS WSGSSPSCLP CRCSTPVIEY GTVNGTDFDC GKAARIQCFK 970 980 990 1000 1010 1020 GFKLLGLSEI TCEADGQWSS GFPHCEHTSC GSLPMIPNAF ISETSSWKEN VITYSCRSGY 1030 1040 1050 1060 1070 1080 VIQGSSDLIC TEKGVWSQPY PVCEPLSCGS PPSVANAVAT GEAHTYESEV KLRCLEGYTM 1090 1100 1110 1120 1130 1140 DTDTDTFTCQ KDGRWFPERI SCSPKKCPLP ENITHILVHG DDFSVNRQVS VSCAEGYTFE 1150 1160 1170 1180 1190 1200 GVNISVCQLD GTWEPPFSDE SCSPVSCGKP ESPEHGFVVG SKYTFESTII YQCEPGYELE 1210 1220 1230 1240 1250 1260 GNRERVCQEN RQWSGGVAIC KETRCETPLE FLNGKADIEN RTTGPNVVYS CNRGYSLEGP 1270 1280 1290 1300 1310 1320 SEAHCTENGT WSHPVPLCKP NPCPVPFVIP ENALLSEKEF YVDQNVSIKC REGFLLQGHG 1330 1340 1350 1360 1370 1380 IITCNPDETW TQTSAKCEKI SCGPPAHVEN AIARGVHYQY GDMITYSCYS GYMLEGFLRS 1390 1400 1410 1420 1430 1440 VCLENGTWTS PPICRAVCRF PCQNGGICQR PNACSCPEGW MGRLCEEPIC ILPCLNGGRC 1450 1460 1470 1480 1490 VAPYQCDCPP GWTGSRCHTA VCQSPCLNGG KCVRPNRCHC LSSWTGHNCS RKRRTGF
	Isoform 4 [UniParc]. Checksum: B304C96189C62CD1	FASTA	1,546	170,093
	10 20 30 40 50 60 MWPRLAFCCW GLALVSGWAT FQQMSPSRNF SFRLFPETAP GAPGSIPAPP APGDEAAGSR 70 80 90 100 110 120 VERLGQAFRR RVRLLRELSE RLELVFLVDD SSSVGEVNFR SELMFVRKLL SDFPVVPTAT 130 140 150 160 170 180 RVAIVTFSSK NYVVPRVDYI STRRARQHKC ALLLQEIPAI SYRGGGTYTK GAFQQAAQIL 190 200 210 220 230 240 LHARENSTKV VFLITDGYSN GGDPRPIAAS LRDSGVEIFT FGIWQGNIRE LNDMASTPKE 250 260 270 280 290 300 EHCYLLHSFE EFEALARRAL HEDLPSGSFI QDDMVHCSYL CDEGKDCCDR MGSCKCGTHT 310 320 330 340 350 360 GHFECICEKG YYGKGLQYEC TACPSGTYKP EGSPGGISSC IPCPDENHTS PPGSTSPEDC 370 380 390 400 410 420 VCREGYRASG QTCELVHCPA LKPPENGYFI QNTCNNHFNA ACGVRCHPGF DLVGSSIILC 430 440 450 460 470 480 LPNGLWSGSE SYCRVRTCPH LRQPKHGHIS CSTREMLYKT TCLVACDEGY RLEGSDKLTC 490 500 510 520 530 540 QGNSQWDGPE PRCVERHCST FQMPKDVIIS PHNCGKQPAK FGTICYVSCR QGFILSGVKE 550 560 570 580 590 600 MLRCTTSGKW NVGVQAAVCK DVEAPQINCP KDIEAKTLEQ QDSANVTWQI PTAKDNSGEK 610 620 630 640 650 660 VSVHVHPAFT PPYLFPIGDV AIVYTATDLS GNQASCIFHI KVIDAEPPVI DWCRSPPPVQ 670 680 690 700 710 720 VSEKVHAASW DEPQFSDNSG AELVITRSHT QGDLFPQGET IVQYTATDPS GNNRTCDIHI 730 740 750 760 770 780 VIKGSPCEIP FTPVNGDFIC TPDNTGVNCT LTCLEGYDFT EGSTDKYYCA YEDGVWKPTY 790 800 810 820 830 840 TTEWPDCAKK RFANHGFKSF EMFYKAARCD DTDLMKKFSE AFETTLGKMV PSFCSDAEDI 850 860 870 880 890 900 DCRLEENLTK KYCLEYNYDY ENGFAIGPGG WGAANRLDYS YDDFLDTVQE TATSIGNAKS 910 920 930 940 950 960 SRIKRSAPLS DYKIKLIFNI TASVPLPDER NDTLEWENQQ RLLQTLETIT NKLKRTLNKD 970 980 990 1000 1010 1020 PMYSFQLASE ILIADSNSLE TKKASPFCRP GSVLRGRMCV NCPLGTYYNL EHFTCESCRI 1030 1040 1050 1060 1070 1080 GSYQDEEGQL ECKLCPSGMY TEYIHSRNIS DCKAQCKQGT YSYSGLETCE SCPLGTYQPK 1090 1100 1110 1120 1130 1140 FGSRSCLSCP ENTSTVKRGA VNISACGVPC PEGKFSRSGL MPCHPCPRDY YQPNAGKAFC 1150 1160 1170 1180 1190 1200 LACPFYGTTP FAGSRSITEC SSFSSTFSAA EESVVPPASL GHIKKRHEIS SQVFHECFFN 1210 1220 1230 1240 1250 1260 PCHNSGTCQQ LGRGYVCLCP LGYTGLKCET DIDECSPLPC LNNGVCKDLV GEFICECPSG 1270 1280 1290 1300 1310 1320 YTGQRCEENI NECSSSPCLN KGICVDGVAG YRCTCVKGFV GLHCETEVNE CQSNPCLNNA 1330 1340 1350 1360 1370 1380 VCEDQVGGFL CKCPPGFLGT RCGKNVDECL SQPCKNGATC KDGANSFRCL CAAGFTGSHC 1390 1400 1410 1420 1430 1440 ELNINECQSN PCRNQATCVD ELNSYSCKCQ PGFSGKRCET EQSTGFNLDF EVSGIYGYVM 1450 1460 1470 1480 1490 1500 LDGMLPSLHA LTCTFWMKSS DDMNYGTPIS YAVDNGSDNT LLLTDYNGWV LYVNGREKIT 1510 1520 1530 1540 NCPSVNDGRW HHIAITWTSA NGIWKVYIDG KLSDGGAGLS VGLPIP

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Molecular and cellular characterization of SEL-OB/SVEP1 in osteogenic cells in vivo and in vitro." Shur I., Socher R., Hameiri M., Fried A., Benayahu D. J. Cell. Physiol. 206:420-427(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
[2]	Han J., Fang Y., Yan J., Ye Q. Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3). Tissue: Mammary gland.
[3]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 195-3571 (ISOFORM 4), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 318-868 (ISOFORM 2), VARIANTS ALA-332 AND VAL-2750. Tissue: Placenta.
[4]	"DNA sequence and analysis of human chromosome 9." Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L. , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I. Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[5]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2). Tissue: Placenta.
[6]	"The full-ORF clone resource of the German cDNA consortium." Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I. BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 2131-3571, VARIANT ILE-3161. Tissue: Colon endothelium.
[7]	"Humoral immunity to human breast cancer: antigen definition and quantitative analysis of mRNA expression." Scanlan M.J., Gout I., Gordon C.M., Williamson B., Stockert E., Gure A.O., Jaeger D., Chen Y.-T., Mackay A., O'Hare M.J., Old L.J. Cancer Immun. 1:4-4(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 2269-2756. Tissue: Mammary gland.
[8]	"Polydom: a secreted protein with pentraxin, complement control protein, epidermal growth factor and von Willebrand factor A domains." Gilges D., Vinit M.-A., Callebaut I., Coulombel L., Cacheux V., Romeo P.-H., Vigon I. Biochem. J. 352:49-59(2000) [PubMed] [Europe PMC] [Abstract] Cited for: TISSUE SPECIFICITY.
[9]	"Human urinary glycoproteomics; attachment site specific analysis of N-and O-linked glycosylations by CID and ECD." Halim A., Nilsson J., Ruetschi U., Hesse C., Larson G. Mol. Cell. Proteomics 0:0-0(2011) [PubMed] [Europe PMC] [Abstract] Cited for: GLYCOSYLATION, STRUCTURE OF CARBOHYDRATES, MASS SPECTROMETRY.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ619977 mRNA. Translation: CAF04067.1. AY916667 mRNA. Translation: AAX12481.1. AK023591 mRNA. Translation: BAB14617.1. Different initiation. AK075235 mRNA. Translation: BAC11489.1. AK027870 mRNA. Translation: BAB55420.1. Different initiation. AL158158 Genomic DNA. Translation: CAI14071.1. AL592463, AL354982 Genomic DNA. Translation: CAH73557.1. Different initiation. AL592463, AL158158, AL354982 Genomic DNA. Translation: CAH73558.1. Sequence problems. AL354982, AL592463 Genomic DNA. Translation: CAH74138.1. Different initiation. AL354982, AL158158, AL592463 Genomic DNA. Translation: CAH74139.1. Sequence problems. AL158158, AL354982, AL592463 Genomic DNA. Translation: CAI14068.1. Sequence problems. BC030816 mRNA. Translation: AAH30816.1. BX537918 mRNA. Translation: CAD97901.1. BX538049 mRNA. Translation: CAD97988.1. AF308289 mRNA. Translation: AAG48257.1. Sequence problems.
IPI	IPI00885181. IPI00939415. IPI00965068. IPI01012873.
RefSeq	NP_699197.3. NM_153366.3.
UniGene	Hs.522334. Hs.726867.
3D structure databases
HSSP	HSSP built from PDB template 1NZI based on UniProtKB Q9UCV4.
ProteinModelPortal	Q4LDE5.
SMR	Q4LDE5. Positions 79-255, 313-507, 1195-1419, 1445-3565.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q4LDE5. 6 interactions.
MINT	MINT-1197821.
PTM databases
PhosphoSite	Q4LDE5.
Polymorphism databases
DMDM	296452942.
Proteomic databases
PaxDb	Q4LDE5.
PRIDE	Q4LDE5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000297826; ENSP00000297826; ENSG00000165124. ENST00000374461; ENSP00000363585; ENSG00000165124. ENST00000374469; ENSP00000363593; ENSG00000165124. ENST00000401783; ENSP00000384917; ENSG00000165124.
GeneID	79987.
KEGG	hsa:79987.
UCSC	uc004beu.2. human. uc010mty.3. human. uc010mtz.3. human. uc010mua.1. human.
Organism-specific databases
CTD	79987.
GeneCards	GC09M113127.
H-InvDB	HIX0008277. HIX0035094.
HGNC	HGNC:15985. SVEP1.
HPA	HPA020610. HPA021520.
MIM	611691. gene.
neXtProt	NX_Q4LDE5.
PharmGKB	PA25971.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG12793.
HOVERGEN	HBG108523.
OMA	IDCRLED.
Gene expression databases
ArrayExpress	Q4LDE5.
Bgee	Q4LDE5.
Genevestigator	Q4LDE5.
Family and domain databases
Gene3D	2.40.155.10. 1 hit. 2.60.120.200. 1 hit.
InterPro	IPR008985. ConA-like_lec_gl_sf. IPR013320. ConA-like_subgrp. IPR000742. EG-like_dom. IPR001881. EGF-like_Ca-bd. IPR013032. EGF-like_CS. IPR000152. EGF-type_Asp/Asn_hydroxyl_site. IPR018097. EGF_Ca-bd_CS. IPR023413. GFP_like. IPR009030. Growth_fac_rcpt. IPR003410. Hyalin. IPR001759. Pentaxin. IPR000436. Sushi_SCR_CCP. IPR011641. Tyr-kin_ephrin_A/B_rcpt-like. IPR002035. VWF_A. [Graphical view]
Pfam	PF00008. EGF. 5 hits. PF07645. EGF_CA. 1 hit. PF07699. GCC2_GCC3. 4 hits. PF12661. hEGF. 1 hit. PF02494. HYR. 2 hits. PF00354. Pentaxin. 1 hit. PF00084. Sushi. 32 hits. PF00092. VWA. 1 hit. [Graphical view]
PRINTS	PR00895. PENTAXIN.
SMART	SM00032. CCP. 34 hits. SM00181. EGF. 4 hits. SM00179. EGF_CA. 6 hits. SM00327. VWA. 1 hit. [Graphical view]
SUPFAM	SSF57535. Complement_control_module. 33 hits. SSF49899. ConA_like_lec_gl. 1 hit. SSF57184. Grow_fac_recept. 2 hits.
PROSITE	PS00010. ASX_HYDROXYL. 6 hits. PS00022. EGF_1. 9 hits. PS01186. EGF_2. 11 hits. PS50026. EGF_3. 9 hits. PS01187. EGF_CA. 6 hits. PS50825. HYR. 2 hits. PS50923. SUSHI. 34 hits. PS50234. VWFA. 1 hit. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	79987.
NextBio	70034.
SOURCE	Search...

Entry information

Entry name

SVEP1_HUMAN

Accession

Primary (citable) accession number: Q4LDE5
Secondary accession number(s): Q0P675 , Q5D213, Q5T938, Q5VTE4, Q5VTE5, Q7Z387, Q7Z3G3, Q8NBT9, Q96JU7, Q9H284, Q9H8J9

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 26, 2008
Last sequence update:	May 18, 2010
Last modified:	May 1, 2013
This is version 81 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.