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Protein

Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1

Gene

Arap1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Has a preference for ARF1 and ARF5 (By similarity).By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri552 – 57524C4-typePROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GTPase activation

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-MMU-194840. Rho GTPase cycle.
R-MMU-8849469. PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1.

Names & Taxonomyi

Protein namesi
Recommended name:
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1
Alternative name(s):
Centaurin-delta-2By similarity
Short name:
Cnt-d2By similarity
Gene namesi
Name:Arap1Imported
Synonyms:Centd2Imported, Kiaa0782Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:1916960. Arap1.

Subcellular locationi

  • Cytoplasm By similarity
  • Golgi apparatusGolgi stack membrane By similarity; Peripheral membrane protein By similarity
  • Cell membrane By similarity

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Cytoplasm, Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 14521452Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1PRO_0000367029Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei232 – 2321PhosphoserineBy similarity
Modified residuei430 – 4301PhosphoserineBy similarity
Modified residuei506 – 5061PhosphotyrosineBy similarity
Modified residuei740 – 7401PhosphoserineBy similarity
Modified residuei1430 – 14301PhosphoserineBy similarity
Modified residuei1437 – 14371PhosphoserineCombined sources

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ4LDD4.
MaxQBiQ4LDD4.
PaxDbiQ4LDD4.
PeptideAtlasiQ4LDD4.
PRIDEiQ4LDD4.

PTM databases

iPTMnetiQ4LDD4.
PhosphoSiteiQ4LDD4.

Expressioni

Gene expression databases

BgeeiQ4LDD4.
ExpressionAtlasiQ4LDD4. baseline and differential.
GenevisibleiQ4LDD4. MM.

Interactioni

Subunit structurei

Interacts with TNFRSF10A.By similarity

GO - Molecular functioni

Protein-protein interaction databases

BioGridi213630. 1 interaction.
IntActiQ4LDD4. 1 interaction.
STRINGi10090.ENSMUSP00000102624.

Structurei

3D structure databases

ProteinModelPortaliQ4LDD4.
SMRiQ4LDD4. Positions 9-61, 335-420, 539-855, 972-1116.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini6 – 7065SAMPROSITE-ProRule annotationAdd
BLAST
Domaini329 – 42193PH 1PROSITE-ProRule annotationAdd
BLAST
Domaini442 – 53190PH 2PROSITE-ProRule annotationAdd
BLAST
Domaini537 – 662126Arf-GAPPROSITE-ProRule annotationAdd
BLAST
Domaini745 – 852108PH 3PROSITE-ProRule annotationAdd
BLAST
Domaini956 – 1141186Rho-GAPPROSITE-ProRule annotationAdd
BLAST
Domaini1174 – 126390Ras-associatingPROSITE-ProRule annotationAdd
BLAST
Domaini1276 – 1398123PH 4PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 Arf-GAP domain.PROSITE-ProRule annotation
Contains 4 PH domains.PROSITE-ProRule annotation
Contains 1 Ras-associating domain.PROSITE-ProRule annotation
Contains 1 Rho-GAP domain.PROSITE-ProRule annotation
Contains 1 SAM (sterile alpha motif) domain.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri552 – 57524C4-typePROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG1117. Eukaryota.
COG5347. LUCA.
GeneTreeiENSGT00760000118874.
HOVERGENiHBG106625.
InParanoidiQ4LDD4.
KOiK18439.
OMAiGAPETSH.
OrthoDBiEOG7F24T4.
PhylomeDBiQ4LDD4.
TreeFamiTF105769.

Family and domain databases

Gene3Di1.10.150.50. 1 hit.
1.10.555.10. 1 hit.
2.30.29.30. 4 hits.
InterProiIPR001164. ArfGAP.
IPR011993. PH_dom-like.
IPR001849. PH_domain.
IPR000159. RA_dom.
IPR008936. Rho_GTPase_activation_prot.
IPR000198. RhoGAP_dom.
IPR001660. SAM.
IPR013761. SAM/pointed.
[Graphical view]
PfamiPF01412. ArfGap. 1 hit.
PF00169. PH. 3 hits.
PF00788. RA. 1 hit.
PF00620. RhoGAP. 1 hit.
PF07647. SAM_2. 1 hit.
[Graphical view]
PRINTSiPR00405. REVINTRACTNG.
SMARTiSM00105. ArfGap. 1 hit.
SM00233. PH. 5 hits.
SM00324. RhoGAP. 1 hit.
SM00454. SAM. 1 hit.
[Graphical view]
SUPFAMiSSF47769. SSF47769. 1 hit.
SSF48350. SSF48350. 1 hit.
SSF50729. SSF50729. 5 hits.
PROSITEiPS50115. ARFGAP. 1 hit.
PS50003. PH_DOMAIN. 4 hits.
PS50200. RA. 1 hit.
PS50238. RHOGAP. 1 hit.
PS50105. SAM_DOMAIN. 1 hit.
[Graphical view]

Sequences (3)i

Sequence statusi: Complete.

This entry describes 3 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q4LDD4-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAEGYDAALS VAEWLRALHL EQYTALFEQH GLVWATECQG LSDAGLLDMG
60 70 80 90 100
MHLPGHRRRI LAGLHRAHAP PVPLPRPAPR PVPMKRHIFR SPPVPVTPPE
110 120 130 140 150
PPPTAGEDEG LPAAPPIPPR RSCLPPACFT PTSTAAPDPV LPPLPAKRHL
160 170 180 190 200
VEPSVPPVPP RTGPPYPQAS LLAKEELLLP SVSPRSQPEP AETPSTLLPA
210 220 230 240 250
FPQGPLQPPS PPPCPPVIPP KPPRLLPEFD DSDYDDVPEE GPGAPASVMT
260 270 280 290 300
KEEPLPSRVP RAVRVASLLS EGEELSGDDS EDDDDHAYEG IPNGGWPTSG
310 320 330 340 350
LNPPLRSLIP DLPLHPMDEL PGGPTPITPV IKAGWLDKNP PQGSYIYQKR
360 370 380 390 400
WVRLDADYLR YFDSNKDAYS KRFVPVACIC RVAPIGDQKF EVITNNRTFA
410 420 430 440 450
FRAESDVERN EWMQALQQAV VEHRARFRLS SASVLGVRGS EQPDRAGSLE
460 470 480 490 500
LRGFKNKLYV AVTGDKVQLY KNLEEFHLGI GITFIDMNVG NVKEVDRRSF
510 520 530 540 550
DLTTPYRIFS FSADSELEKE QWLEAMQGAI AEALSTSEVA ERIWAAAPNR
560 570 580 590 600
FCADCGAAQP DWASINLCVV ICKRCAGEHR GLGAGVSKVR SLKMDRKVWT
610 620 630 640 650
EALIQLFLHL GNGPGNHFWA ANVPPSEALE PSSSPGARRY HLEAKYREGK
660 670 680 690 700
YRRYHPLFGN QEELDKALCA AVTTTDLAET QALLGCGAGV SCFSGDPAAP
710 720 730 740 750
TPLALAEQAG QTLQMEFLRN NQSTEVPRLD SVKPLEKHYS VTLPTVSHSG
760 770 780 790 800
FLYKTASAGK PLQDRRAREE FSRRWCVLSD GVLSYYENER AVTPNGEIRA
810 820 830 840 850
SEIVCLAVSP LDTHGFEHTF EVYTEGERLY LFGLENAELA HEWVKCIAKA
860 870 880 890 900
FVPPLAEDLL ARDFERLGRL PCKAGLSLQQ AQEGWFALTG SELRAVFPEG
910 920 930 940 950
PWEEPLQLRK LQELSIQGDS ENQVLVLVER RRTLYIQGER RLDFMAWLGV
960 970 980 990 1000
IQKAAASLGD TLSEQQLGDS DIPVIVYRCV DYITQCGLTS EGIYRKCGQT
1010 1020 1030 1040 1050
SKTQRLLDSL RQDARSVHLK EGEQHVDDVS SALKRFLRDL PDGLFTRAQR
1060 1070 1080 1090 1100
LAWLEASEIE DEEEKISRYR ELLVHLPPVN RATVKALISH LYCVQCFSDT
1110 1120 1130 1140 1150
NQMNTHNLAI VFGPTLFQTD GQDYKAGKVV EDLINHYVVV FSVDEEELRK
1160 1170 1180 1190 1200
QREEVTAIVK MRVAGTASGT QHAGDFICTV YLEEKKVETE QHVKIPASMT
1210 1220 1230 1240 1250
AEELTLEILD RRNVSIREKD YWTCFEVNEK EEAERPLHFA EKVLPIVHGL
1260 1270 1280 1290 1300
GIDSHLVVKK YQSMEAMLLY LASRVGDTKH GMMKFREDRS LLGLGLPSGG
1310 1320 1330 1340 1350
FHDRYFILNS SCLRLYKEVR SQRPWSGAPE TSHRPEKEWP VKSLKVYLGV
1360 1370 1380 1390 1400
KKKLRPPTCW GFTVVHETEK HEKQQWYLCC DTQMELREWF ATFLSVQHDG
1410 1420 1430 1440 1450
LVWPSEPSRV SRAVPEVRMG SVSLIPLRGS ENEMRRSVAA FTADPLSLLR

HV
Length:1,452
Mass (Da):162,276
Last modified:March 24, 2009 - v2
Checksum:i1606F3534555D4F6
GO
Isoform 22 Publications (identifier: Q4LDD4-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1322-1332: Missing.

Show »
Length:1,441
Mass (Da):161,079
Checksum:i8F819926E3F6AC40
GO
Isoform 31 Publication (identifier: Q4LDD4-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-248: Missing.
     1322-1332: Missing.

Note: No experimental confirmation available.Curated
Show »
Length:1,193
Mass (Da):134,632
Checksum:i6F5078812234CFE2
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti153 – 1531P → S in AAI41180 (PubMed:15489334).Curated
Sequence conflicti280 – 2801S → A in AAI41180 (PubMed:15489334).Curated
Sequence conflicti924 – 9241V → G in CAF21318 (Ref. 1) Curated
Sequence conflicti1331 – 13311T → R in AAH57922 (PubMed:15489334).Curated

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 248248Missing in isoform 3. 1 PublicationVSP_053047Add
BLAST
Alternative sequencei1322 – 133211Missing in isoform 2 and isoform 3. 2 PublicationsVSP_053048Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ621558 mRNA. Translation: CAF21318.1.
AK137455 mRNA. Translation: BAE23358.1.
AK140646 mRNA. Translation: BAE24434.1.
AK150132 mRNA. Translation: BAE29329.1.
BC057922 mRNA. Translation: AAH57922.1.
BC091762 mRNA. Translation: AAH91762.1.
BC141179 mRNA. Translation: AAI41180.1.
AK129213 mRNA. Translation: BAC98023.1.
CCDSiCCDS21510.1. [Q4LDD4-3]
CCDS40041.1. [Q4LDD4-2]
RefSeqiNP_001035200.1. NM_001040111.1. [Q4LDD4-2]
NP_001035201.1. NM_001040112.1. [Q4LDD4-3]
NP_081456.2. NM_027180.3. [Q4LDD4-3]
NP_932764.1. NM_198096.1.
XP_006508249.1. XM_006508186.2. [Q4LDD4-1]
XP_006508250.1. XM_006508187.1. [Q4LDD4-1]
XP_006508251.1. XM_006508188.2. [Q4LDD4-1]
XP_011240199.1. XM_011241897.1. [Q4LDD4-1]
UniGeneiMm.277687.

Genome annotation databases

EnsembliENSMUST00000084895; ENSMUSP00000081957; ENSMUSG00000032812. [Q4LDD4-3]
ENSMUST00000084896; ENSMUSP00000081958; ENSMUSG00000032812. [Q4LDD4-1]
ENSMUST00000107010; ENSMUSP00000102624; ENSMUSG00000032812. [Q4LDD4-2]
GeneIDi69710.
KEGGimmu:69710.
UCSCiuc009iok.1. mouse. [Q4LDD4-2]
uc009iol.1. mouse. [Q4LDD4-1]
uc009iom.1. mouse. [Q4LDD4-3]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ621558 mRNA. Translation: CAF21318.1.
AK137455 mRNA. Translation: BAE23358.1.
AK140646 mRNA. Translation: BAE24434.1.
AK150132 mRNA. Translation: BAE29329.1.
BC057922 mRNA. Translation: AAH57922.1.
BC091762 mRNA. Translation: AAH91762.1.
BC141179 mRNA. Translation: AAI41180.1.
AK129213 mRNA. Translation: BAC98023.1.
CCDSiCCDS21510.1. [Q4LDD4-3]
CCDS40041.1. [Q4LDD4-2]
RefSeqiNP_001035200.1. NM_001040111.1. [Q4LDD4-2]
NP_001035201.1. NM_001040112.1. [Q4LDD4-3]
NP_081456.2. NM_027180.3. [Q4LDD4-3]
NP_932764.1. NM_198096.1.
XP_006508249.1. XM_006508186.2. [Q4LDD4-1]
XP_006508250.1. XM_006508187.1. [Q4LDD4-1]
XP_006508251.1. XM_006508188.2. [Q4LDD4-1]
XP_011240199.1. XM_011241897.1. [Q4LDD4-1]
UniGeneiMm.277687.

3D structure databases

ProteinModelPortaliQ4LDD4.
SMRiQ4LDD4. Positions 9-61, 335-420, 539-855, 972-1116.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi213630. 1 interaction.
IntActiQ4LDD4. 1 interaction.
STRINGi10090.ENSMUSP00000102624.

PTM databases

iPTMnetiQ4LDD4.
PhosphoSiteiQ4LDD4.

Proteomic databases

EPDiQ4LDD4.
MaxQBiQ4LDD4.
PaxDbiQ4LDD4.
PeptideAtlasiQ4LDD4.
PRIDEiQ4LDD4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000084895; ENSMUSP00000081957; ENSMUSG00000032812. [Q4LDD4-3]
ENSMUST00000084896; ENSMUSP00000081958; ENSMUSG00000032812. [Q4LDD4-1]
ENSMUST00000107010; ENSMUSP00000102624; ENSMUSG00000032812. [Q4LDD4-2]
GeneIDi69710.
KEGGimmu:69710.
UCSCiuc009iok.1. mouse. [Q4LDD4-2]
uc009iol.1. mouse. [Q4LDD4-1]
uc009iom.1. mouse. [Q4LDD4-3]

Organism-specific databases

CTDi116985.
MGIiMGI:1916960. Arap1.
RougeiSearch...

Phylogenomic databases

eggNOGiKOG1117. Eukaryota.
COG5347. LUCA.
GeneTreeiENSGT00760000118874.
HOVERGENiHBG106625.
InParanoidiQ4LDD4.
KOiK18439.
OMAiGAPETSH.
OrthoDBiEOG7F24T4.
PhylomeDBiQ4LDD4.
TreeFamiTF105769.

Enzyme and pathway databases

ReactomeiR-MMU-194840. Rho GTPase cycle.
R-MMU-8849469. PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1.

Miscellaneous databases

ChiTaRSiArap1. mouse.
PROiQ4LDD4.
SOURCEiSearch...

Gene expression databases

BgeeiQ4LDD4.
ExpressionAtlasiQ4LDD4. baseline and differential.
GenevisibleiQ4LDD4. MM.

Family and domain databases

Gene3Di1.10.150.50. 1 hit.
1.10.555.10. 1 hit.
2.30.29.30. 4 hits.
InterProiIPR001164. ArfGAP.
IPR011993. PH_dom-like.
IPR001849. PH_domain.
IPR000159. RA_dom.
IPR008936. Rho_GTPase_activation_prot.
IPR000198. RhoGAP_dom.
IPR001660. SAM.
IPR013761. SAM/pointed.
[Graphical view]
PfamiPF01412. ArfGap. 1 hit.
PF00169. PH. 3 hits.
PF00788. RA. 1 hit.
PF00620. RhoGAP. 1 hit.
PF07647. SAM_2. 1 hit.
[Graphical view]
PRINTSiPR00405. REVINTRACTNG.
SMARTiSM00105. ArfGap. 1 hit.
SM00233. PH. 5 hits.
SM00324. RhoGAP. 1 hit.
SM00454. SAM. 1 hit.
[Graphical view]
SUPFAMiSSF47769. SSF47769. 1 hit.
SSF48350. SSF48350. 1 hit.
SSF50729. SSF50729. 5 hits.
PROSITEiPS50115. ARFGAP. 1 hit.
PS50003. PH_DOMAIN. 4 hits.
PS50200. RA. 1 hit.
PS50238. RHOGAP. 1 hit.
PS50105. SAM_DOMAIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "ARAP1 splice variants in man and mouse."
    Krugmann S., Coadwell J., Stephens L.R., Hawkins P.T.
    Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
    Strain: C57BL/6J.
  2. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3).
    Strain: C57BL/6JImported.
    Tissue: BoneImported, Bone marrow macrophageImported and CerebellumImported.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1320-1452 (ISOFORM 2/3).
    Strain: FVB/NImported.
    Tissue: BrainImported and LiverImported.
  4. "Prediction of the coding sequences of mouse homologues of KIAA gene: III. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
    Okazaki N., Kikuno R., Ohara R., Inamoto S., Koseki H., Hiraoka S., Saga Y., Nagase T., Ohara O., Koga H.
    DNA Res. 10:167-180(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 295-1452 (ISOFORM 2/3).
    Tissue: BrainImported.
  5. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1437, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Brain, Brown adipose tissue, Kidney, Lung, Pancreas, Spleen and Testis.

Entry informationi

Entry nameiARAP1_MOUSE
AccessioniPrimary (citable) accession number: Q4LDD4
Secondary accession number(s): B2RUJ3
, Q3UDD2, Q3US99, Q58ET6, Q6PEQ9, Q6ZQ48
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: March 24, 2009
Last modified: July 6, 2016
This is version 111 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.