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Protein

Sulfate adenylyltransferase

Gene

sat

Organism
Staphylococcus haemolyticus (strain JCSC1435)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + sulfate = diphosphate + adenylyl sulfate.UniRule annotation

Pathwayi: hydrogen sulfide biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes sulfite from sulfate.UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. Sulfate adenylyltransferase (sat)
  2. Adenylyl-sulfate kinase (cysC)
  3. Phosphoadenosine phosphosulfate reductase (cysH)
This subpathway is part of the pathway hydrogen sulfide biosynthesis, which is itself part of Sulfur metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes sulfite from sulfate, the pathway hydrogen sulfide biosynthesis and in Sulfur metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferase, Transferase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSHAE279808:G1G27-393-MONOMER
UniPathwayiUPA00140; UER00204

Names & Taxonomyi

Protein namesi
Recommended name:
Sulfate adenylyltransferaseUniRule annotation (EC:2.7.7.4UniRule annotation)
Alternative name(s):
ATP-sulfurylaseUniRule annotation
Sulfate adenylate transferaseUniRule annotation
Short name:
SATUniRule annotation
Gene namesi
Name:satUniRule annotation
Ordered Locus Names:SH0419
OrganismiStaphylococcus haemolyticus (strain JCSC1435)
Taxonomic identifieri279808 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000000543 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000090431 – 392Sulfate adenylyltransferaseAdd BLAST392

Interactioni

Protein-protein interaction databases

STRINGi279808.SH0419

Structurei

3D structure databases

SMRiQ4L9E7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the sulfate adenylyltransferase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107RIQ Bacteria
COG2046 LUCA
HOGENOMiHOG000069044
KOiK00958
OMAiRMRCYEI
OrthoDBiPOG091H0GMI

Family and domain databases

CDDicd00517 ATPS, 1 hit
Gene3Di3.40.50.620, 1 hit
HAMAPiMF_00066 Sulf_adenylyltr, 1 hit
InterProiView protein in InterPro
IPR025980 ATP-Sase_PUA-like_dom
IPR015947 PUA-like_sf
IPR014729 Rossmann-like_a/b/a_fold
IPR020792 SO4_adenylyltransferase_pro
IPR024951 Sulfurylase_cat_dom
IPR002650 Sulphate_adenylyltransferase
PfamiView protein in Pfam
PF01747 ATP-sulfurylase, 1 hit
PF14306 PUA_2, 1 hit
SUPFAMiSSF88697 SSF88697, 1 hit
TIGRFAMsiTIGR00339 sopT, 1 hit

Sequencei

Sequence statusi: Complete.

Q4L9E7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTHEQIINY TIKPHGGTLI NRVVEGEERD HLLEAAQSYK VITLNPWSIS
60 70 80 90 100
DLELIGIGGF SPLTGFMGVA DYTKVVEDTH LENGLVWSIP ITLPVTEEEA
110 120 130 140 150
DKLEIGDDIA LYGEDGELYG TLKLEEKYTY DKKKEAQNVY GTTDEAHPGV
160 170 180 190 200
KKVYDKGNVY LAGPIQLINR PKHDEFSDFH LDPAETRQLF HDLGWKTVVG
210 220 230 240 250
FQTRNPVHRA HEYIQKSALE IVDGLLLNPL VGETKSDDIP ANVRMESYQA
260 270 280 290 300
ILKNYFPKDR ARLVIYPAAM RYAGPREAIL HATVRKNYGC THFIVGRDHA
310 320 330 340 350
GVGDYYGTYE AQELISQFED ELDIQILKFE HAFYCEKCGN MATAKTCPHD
360 370 380 390
ASEHVHLSGT KVREKLRNGE SLPTKFSRPE VAEVLIKGLK QN
Length:392
Mass (Da):44,217
Last modified:August 2, 2005 - v1
Checksum:iAB6B2AAABD4531C6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006716 Genomic DNA Translation: BAE03728.1
RefSeqiWP_011274745.1, NC_007168.1

Genome annotation databases

EnsemblBacteriaiBAE03728; BAE03728; SH0419
GeneIDi24247263
KEGGisha:SH0419

Similar proteinsi

Entry informationi

Entry nameiSAT_STAHJ
AccessioniPrimary (citable) accession number: Q4L9E7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 2, 2005
Last modified: April 25, 2018
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health