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Protein

Sulfate adenylyltransferase

Gene

sat

Organism
Staphylococcus haemolyticus (strain JCSC1435)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + sulfate = diphosphate + adenylyl sulfate.UniRule annotation

Pathwayi: hydrogen sulfide biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes sulfite from sulfate.UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. Sulfate adenylyltransferase (sat)
  2. Adenylyl-sulfate kinase (cysC)
  3. Phosphoadenosine phosphosulfate reductase (cysH)
This subpathway is part of the pathway hydrogen sulfide biosynthesis, which is itself part of Sulfur metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes sulfite from sulfate, the pathway hydrogen sulfide biosynthesis and in Sulfur metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSHAE279808:GJX7-421-MONOMER.
UniPathwayiUPA00140; UER00204.

Names & Taxonomyi

Protein namesi
Recommended name:
Sulfate adenylyltransferaseUniRule annotation (EC:2.7.7.4UniRule annotation)
Alternative name(s):
ATP-sulfurylaseUniRule annotation
Sulfate adenylate transferaseUniRule annotation
Short name:
SATUniRule annotation
Gene namesi
Name:satUniRule annotation
Ordered Locus Names:SH0419
OrganismiStaphylococcus haemolyticus (strain JCSC1435)
Taxonomic identifieri279808 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000000543 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 392392Sulfate adenylyltransferasePRO_1000009043Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi279808.SH0419.

Family & Domainsi

Sequence similaritiesi

Belongs to the sulfate adenylyltransferase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107RIQ. Bacteria.
COG2046. LUCA.
HOGENOMiHOG000069044.
KOiK00958.
OMAiLQHMIIR.
OrthoDBiPOG091H0GMI.

Family and domain databases

CDDicd00517. ATPS. 1 hit.
Gene3Di3.40.50.620. 1 hit.
HAMAPiMF_00066. Sulf_adenylyltr. 1 hit.
InterProiIPR025980. ATP-Sase_PUA-like_dom.
IPR015947. PUA-like_domain.
IPR014729. Rossmann-like_a/b/a_fold.
IPR020792. SO4_adenylyltransferase_pro.
IPR024951. Sulfurylase_cat_dom.
IPR002650. Sulphate_adenylyltransferase.
[Graphical view]
PfamiPF01747. ATP-sulfurylase. 1 hit.
PF14306. PUA_2. 1 hit.
[Graphical view]
SUPFAMiSSF88697. SSF88697. 1 hit.
TIGRFAMsiTIGR00339. sopT. 1 hit.

Sequencei

Sequence statusi: Complete.

Q4L9E7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTHEQIINY TIKPHGGTLI NRVVEGEERD HLLEAAQSYK VITLNPWSIS
60 70 80 90 100
DLELIGIGGF SPLTGFMGVA DYTKVVEDTH LENGLVWSIP ITLPVTEEEA
110 120 130 140 150
DKLEIGDDIA LYGEDGELYG TLKLEEKYTY DKKKEAQNVY GTTDEAHPGV
160 170 180 190 200
KKVYDKGNVY LAGPIQLINR PKHDEFSDFH LDPAETRQLF HDLGWKTVVG
210 220 230 240 250
FQTRNPVHRA HEYIQKSALE IVDGLLLNPL VGETKSDDIP ANVRMESYQA
260 270 280 290 300
ILKNYFPKDR ARLVIYPAAM RYAGPREAIL HATVRKNYGC THFIVGRDHA
310 320 330 340 350
GVGDYYGTYE AQELISQFED ELDIQILKFE HAFYCEKCGN MATAKTCPHD
360 370 380 390
ASEHVHLSGT KVREKLRNGE SLPTKFSRPE VAEVLIKGLK QN
Length:392
Mass (Da):44,217
Last modified:August 2, 2005 - v1
Checksum:iAB6B2AAABD4531C6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006716 Genomic DNA. Translation: BAE03728.1.
RefSeqiWP_011274745.1. NC_007168.1.

Genome annotation databases

EnsemblBacteriaiBAE03728; BAE03728; SH0419.
GeneIDi24247263.
KEGGisha:SH0419.
PATRICi19616871. VBIStaHae67511_0412.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006716 Genomic DNA. Translation: BAE03728.1.
RefSeqiWP_011274745.1. NC_007168.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi279808.SH0419.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAE03728; BAE03728; SH0419.
GeneIDi24247263.
KEGGisha:SH0419.
PATRICi19616871. VBIStaHae67511_0412.

Phylogenomic databases

eggNOGiENOG4107RIQ. Bacteria.
COG2046. LUCA.
HOGENOMiHOG000069044.
KOiK00958.
OMAiLQHMIIR.
OrthoDBiPOG091H0GMI.

Enzyme and pathway databases

UniPathwayiUPA00140; UER00204.
BioCyciSHAE279808:GJX7-421-MONOMER.

Family and domain databases

CDDicd00517. ATPS. 1 hit.
Gene3Di3.40.50.620. 1 hit.
HAMAPiMF_00066. Sulf_adenylyltr. 1 hit.
InterProiIPR025980. ATP-Sase_PUA-like_dom.
IPR015947. PUA-like_domain.
IPR014729. Rossmann-like_a/b/a_fold.
IPR020792. SO4_adenylyltransferase_pro.
IPR024951. Sulfurylase_cat_dom.
IPR002650. Sulphate_adenylyltransferase.
[Graphical view]
PfamiPF01747. ATP-sulfurylase. 1 hit.
PF14306. PUA_2. 1 hit.
[Graphical view]
SUPFAMiSSF88697. SSF88697. 1 hit.
TIGRFAMsiTIGR00339. sopT. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiSAT_STAHJ
AccessioniPrimary (citable) accession number: Q4L9E7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 2, 2005
Last modified: September 7, 2016
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.