Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

D-specific D-2-hydroxyacid dehydrogenase

Gene

ddh

Organism
Staphylococcus haemolyticus (strain JCSC1435)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. NAD binding Source: InterPro
  2. oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Enzyme and pathway databases

BioCyciSHAE279808:GJX7-547-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
D-specific D-2-hydroxyacid dehydrogenaseImported
Gene namesi
Name:ddhImported
Ordered Locus Names:SH0545Imported
OrganismiStaphylococcus haemolyticus (strain JCSC1435)Imported
Taxonomic identifieri279808 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
ProteomesiUP000000543: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi279808.SH0545.

Structurei

3D structure databases

ProteinModelPortaliQ4L921.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1052.
HOGENOMiHOG000136695.
KOiK03778.
OMAiTWGLPIR.
OrthoDBiEOG61VZ8G.

Family and domain databases

Gene3Di3.40.50.720. 2 hits.
InterProiIPR006139. D-isomer_2_OHA_DH_cat_dom.
IPR029753. D-isomer_DH_CS.
IPR029752. D-isomer_DH_CS1.
IPR006140. D-isomer_DH_NAD-bd.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF00389. 2-Hacid_dh. 1 hit.
PF02826. 2-Hacid_dh_C. 1 hit.
[Graphical view]
PROSITEiPS00065. D_2_HYDROXYACID_DH_1. 1 hit.
PS00670. D_2_HYDROXYACID_DH_2. 1 hit.
PS00671. D_2_HYDROXYACID_DH_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4L921-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKIMFYGTR DYEKNDALNW GKANNVEVVT TEEILSEDTV DLAKGFDGVT
60 70 80 90 100
TMQFGKLADS VYPKLEEYGI KQIAQRTAGF DMYDLELAKK HGIIISNVPS
110 120 130 140 150
YSPETIAEYS VSIALQLVRR FPAIEKRVQE HNFKWAAPIM STPVKNMTVA
160 170 180 190 200
IIGTGRIGAA TGKIYAGFGA KVVGYDAYPN NSLDFLEYKD TVEEAIADAD
210 220 230 240 250
IISLHVPANK ESFHLFDADM FSKVKKGAVL VNAARGAVID TPELIKAIND
260 270 280 290 300
GTLYGAAIDT YENEAPYFTY DWTGKEIEDE TLLELIKHEN ILVTPHIAFF
310 320 330
SDEAVRNLVE GGLNAALSVI NTGKCETQLN
Length:330
Mass (Da):36,415
Last modified:August 2, 2005 - v1
Checksum:i68416525C8A1AF7E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006716 Genomic DNA. Translation: BAE03854.1.
RefSeqiYP_252460.1. NC_007168.1.

Genome annotation databases

EnsemblBacteriaiBAE03854; BAE03854; SH0545.
GeneIDi3482295.
KEGGisha:SH0545.
PATRICi19617117. VBIStaHae67511_0535.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006716 Genomic DNA. Translation: BAE03854.1.
RefSeqiYP_252460.1. NC_007168.1.

3D structure databases

ProteinModelPortaliQ4L921.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi279808.SH0545.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAE03854; BAE03854; SH0545.
GeneIDi3482295.
KEGGisha:SH0545.
PATRICi19617117. VBIStaHae67511_0535.

Phylogenomic databases

eggNOGiCOG1052.
HOGENOMiHOG000136695.
KOiK03778.
OMAiTWGLPIR.
OrthoDBiEOG61VZ8G.

Enzyme and pathway databases

BioCyciSHAE279808:GJX7-547-MONOMER.

Family and domain databases

Gene3Di3.40.50.720. 2 hits.
InterProiIPR006139. D-isomer_2_OHA_DH_cat_dom.
IPR029753. D-isomer_DH_CS.
IPR029752. D-isomer_DH_CS1.
IPR006140. D-isomer_DH_NAD-bd.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF00389. 2-Hacid_dh. 1 hit.
PF02826. 2-Hacid_dh_C. 1 hit.
[Graphical view]
PROSITEiPS00065. D_2_HYDROXYACID_DH_1. 1 hit.
PS00670. D_2_HYDROXYACID_DH_2. 1 hit.
PS00671. D_2_HYDROXYACID_DH_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Whole-genome sequencing of Staphylococcus haemolyticus uncovers the extreme plasticity of its genome and the evolution of human-colonizing staphylococcal species."
    Takeuchi F., Watanabe S., Baba T., Yuzawa H., Ito T., Morimoto Y., Kuroda M., Cui L., Takahashi M., Ankai A., Baba S., Fukui S., Lee J.C., Hiramatsu K.
    J. Bacteriol. 187:7292-7308(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JCSC1435Imported.

Entry informationi

Entry nameiQ4L921_STAHJ
AccessioniPrimary (citable) accession number: Q4L921
Entry historyi
Integrated into UniProtKB/TrEMBL: August 2, 2005
Last sequence update: August 2, 2005
Last modified: March 4, 2015
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.