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Q4L8N5 (FENR_STAHJ) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferredoxin--NADP reductase
Short name=FNR
Short name=Fd-NADP+ reductase
EC=1.18.1.2
Gene names
Ordered Locus Names:SH0681
OrganismStaphylococcus haemolyticus (strain JCSC1435) [Complete proteome] [HAMAP]
Taxonomic identifier279808 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length343 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH. HAMAP MF_01685

Cofactor

Binds 1 FAD per subunit By similarity. HAMAP MF_01685

Subunit structure

Homodimer By similarity. HAMAP MF_01685

Sequence similarities

Belongs to the ferredoxin--NADP reductase type 2 family.

Ontologies

Keywords
   LigandFAD
Flavoprotein
NADP
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functionferredoxin-NADP+ reductase activity

Inferred from electronic annotation. Source: EC

flavin adenine dinucleotide binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 343343Ferredoxin--NADP reductase HAMAP MF_01685
PRO_0000364948

Sites

Binding site311FAD By similarity
Binding site391FAD By similarity
Binding site431FAD By similarity
Binding site831FAD; via amide nitrogen and carbonyl oxygen By similarity
Binding site1181FAD; via amide nitrogen By similarity
Binding site2851FAD By similarity
Binding site3261FAD By similarity

Sequences

Sequence LengthMass (Da)Tools
Q4L8N5 [UniParc].

Last modified August 2, 2005. Version 1.
Checksum: 069BD6E6E9DDE53E

FASTA34337,953
        10         20         30         40         50         60 
MQDVTIIGGG PAGLFASFYA GLRGMSVRII DVQDKLGGKM QIYPEKIIWD IGGVAPKPCN 

        70         80         90        100        110        120 
EIIKDMINQG LHFNPKVNLN ERVTDIRKIA ERHFEVETDS GQIYESKAVI FAVGGGIINP 

       130        140        150        160        170        180 
KPLQIKDAER YRLTNLHYVV QSFSKFKGKD ILISGGGNTA LDWARDLANI ANSITLVYRK 

       190        200        210        220        230        240 
SDIKGYEAMI SVLKALNVNL LPKTQIKELI GDNKCECIKE VKLENIETGE VTTQAFDDVI 

       250        260        270        280        290        300 
VSHGFDHENP LLKDCTSKLD LYDEYRVKGF GNTTTNIPGI FACGDIVHHD AKVHLIASAF 

       310        320        330        340 
SDAGNAANLA KTYINPDAYK EGYVSSHNDV FKESNKKVIN QYI

« Hide

References

[1]"Whole-genome sequencing of Staphylococcus haemolyticus uncovers the extreme plasticity of its genome and the evolution of human-colonizing staphylococcal species."
Takeuchi F., Watanabe S., Baba T., Yuzawa H., Ito T., Morimoto Y., Kuroda M., Cui L., Takahashi M., Ankai A., Baba S., Fukui S., Lee J.C., Hiramatsu K.
J. Bacteriol. 187:7292-7308(2005) [PubMed: 16237012] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JCSC1435.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP006716 Genomic DNA. Translation: BAE03990.1.
RefSeqYP_252596.1. NC_007168.1.

3D structure databases

ProteinModelPortalQ4L8N5.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ4L8N5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBSTAT00000046007; EBSTAP00000044458; EBSTAG00000046004.
GeneID3484270.
GenomeReviewsGene locus SH0681 in contig AP006716_GR.
KEGGsha:SH0681.
NMPDRfig|279808.3.peg.769.
PATRIC19617384. VBIStaHae67511_0668.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0492.
GeneTreeEBGT00050000023768.
HOGENOMHBG669726.
OMAFNTSITK.
PhylomeDBQ4L8N5.
ProtClustDBCLSK885935.

Enzyme and pathway databases

BioCycSHAE279808:SH0681-MONOMER.

Family and domain databases

HAMAPMF_01685. FENR2.
[Tree]
InterProIPR013027. FAD_pyr_nucl-diS_OxRdtase.
IPR022890. Fd--NADP_Rdtase_type_2.
IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD.
IPR001327. Pyr_OxRdtase_NAD-bd_dom.
IPR000103. Pyridine_nuc-diS_OxRdtase_2.
[Graphical view]
KOK00384.
PANTHERPTHR22912:SF53. PTHR22912:SF53. 1 hit.
PfamPF00070. Pyr_redox. 1 hit.
PF07992. Pyr_redox_2. 1 hit.
[Graphical view]
PRINTSPR00368. FADPNR.
PR00469. PNDRDTASEII.
ProtoNetSearch...

Entry information

Entry nameFENR_STAHJ
AccessionPrimary (citable) accession number: Q4L8N5
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: August 2, 2005
Last modified: January 25, 2012
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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