Q4L874 (LACA_STAHJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Galactose-6-phosphate isomerase subunit lacA
EC=5.3.1.26

Gene names

Name:	lacA
Ordered Locus Names:	SH0842

Organism

Staphylococcus haemolyticus (strain JCSC1435) [Complete proteome] [HAMAP]

Taxonomic identifier

279808 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	142 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-galactose 6-phosphate = D-tagatose 6-phosphate. HAMAP MF_01555
Pathway	Carbohydrate metabolism; D-galactose 6-phosphate degradation; D-tagatose 6-phosphate from D-galactose 6-phosphate: step 1/1. HAMAP MF_01555
Subunit structure	Heteromultimeric protein consisting of lacA and lacB By similarity.
Sequence similarities	Belongs to the lacAB/rpiB family.

Ontologies

Keywords
Biological process	Lactose metabolism
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lactose catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	galactose-6-phosphate isomerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 142	142	Galactose-6-phosphate isomerase subunit lacA HAMAP MF_01555		PRO_0000208114

Sequences

	Sequence		Length	Mass (Da)
	Q4L874 [UniParc]. Last modified August 2, 2005. Version 1. Checksum: 7E21D1FEFA09B7C0	FASTA	142	15,509
	10 20 30 40 50 60 MTIFIGSDVA GQRLKDVVKT FLKENNHDVV DVTEGKELDF VDSTLAVVHE VQKNDDNLGI 70 80 90 100 110 120 AVDAYGAGSF IVATKVKGMI AAEVSDERSA YMTRSHNNAC MITMGSEIVG DTLAKNIAKE 130 140 FVNGHYDGGR HQIRVDMLNK MC

References

[1]

"Whole-genome sequencing of Staphylococcus haemolyticus uncovers the extreme plasticity of its genome and the evolution of human-colonizing staphylococcal species." Takeuchi F., Watanabe S., Baba T., Yuzawa H., Ito T., Morimoto Y., Kuroda M., Cui L., Takahashi M., Ankai A., Baba S., Fukui S., Lee J.C., Hiramatsu K. J. Bacteriol. 187:7292-7308(2005) [PubMed: 16237012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: JCSC1435.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP006716 Genomic DNA. Translation: BAE04151.1.
RefSeq	YP_252757.1. NC_007168.1.
3D structure databases
ProteinModelPortal	Q4L874.
ModBase	Search...
Protein-protein interaction databases
STRING	Q4L874.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTAT00000046564; EBSTAP00000045015; EBSTAG00000046561.
GeneID	3482140.
GenomeReviews	Gene locus SH0842 in contig AP006716_GR.
KEGG	sha:SH0842.
NMPDR	fig|279808.3.peg.855.
PATRIC	19617702. VBIStaHae67511_0827.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0698.
GeneTree	EBGT00050000024804.
HOGENOM	HBG636953.
OMA	ARMITVG.
ProtClustDB	PRK08621.
Enzyme and pathway databases
BioCyc	SHAE279808:SH0842-MONOMER.
Family and domain databases
HAMAP	MF_01555. LacA. [Tree]
InterPro	IPR004783. Gal-6-P_isomerase_su_LacA. IPR003500. Rib/Gal_isomrase. [Graphical view]
Gene3D	G3DSA:3.40.1400.10. Rib/Gal_isomrase. 1 hit.
KO	K01819.
Pfam	PF02502. LacAB_rpiB. 1 hit. [Graphical view]
PIRSF	PIRSF005384. RpiB_LacA_B. 1 hit.
SUPFAM	SSF89623. Rib/Gal_isomrase. 1 hit.
TIGRFAMs	TIGR01118. LacA. 1 hit. TIGR00689. RpiB_lacA_lacB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

LACA_STAHJ

Accession

Primary (citable) accession number: Q4L874

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 20, 2005
Last sequence update:	August 2, 2005
Last modified:	January 25, 2012
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program