Q4L873 (LACB_STAHJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Galactose-6-phosphate isomerase subunit lacB
EC=5.3.1.26

Gene names

Name:	lacB
Ordered Locus Names:	SH0843

Organism

Staphylococcus haemolyticus (strain JCSC1435) [Complete proteome] [HAMAP]

Taxonomic identifier

279808 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	171 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-galactose 6-phosphate = D-tagatose 6-phosphate. HAMAP MF_01556
Pathway	Carbohydrate metabolism; D-galactose 6-phosphate degradation; D-tagatose 6-phosphate from D-galactose 6-phosphate: step 1/1. HAMAP MF_01556
Subunit structure	Heteromultimeric protein consisting of lacA and lacB By similarity.
Sequence similarities	Belongs to the lacAB/rpiB family.

Ontologies

Keywords
Biological process	Lactose metabolism
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lactose catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	galactose-6-phosphate isomerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 171	171	Galactose-6-phosphate isomerase subunit lacB HAMAP MF_01556		PRO_0000208145

Sequences

	Sequence		Length	Mass (Da)
	Q4L873 [UniParc]. Last modified August 2, 2005. Version 1. Checksum: B47A3CFFE671DB87	FASTA	171	18,869
	10 20 30 40 50 60 MKIAIGCDHI VTDTKMEVSQ HLKAQGHEVI DVGTYDFTRT HYPIFGKKVG EKVASGEADL 70 80 90 100 110 120 GVCICGTGVG ISNAANKVPG VRTALVRDMT SALYSKEELN ANVVSFGGKV AGELFIFDIV 130 140 150 160 170 DAFIKAEYKP TEENKKLIAK INHLEAHNDN QANPHFFDEF LEKWDKGKYH D

References

[1]

"Whole-genome sequencing of Staphylococcus haemolyticus uncovers the extreme plasticity of its genome and the evolution of human-colonizing staphylococcal species." Takeuchi F., Watanabe S., Baba T., Yuzawa H., Ito T., Morimoto Y., Kuroda M., Cui L., Takahashi M., Ankai A., Baba S., Fukui S., Lee J.C., Hiramatsu K. J. Bacteriol. 187:7292-7308(2005) [PubMed: 16237012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: JCSC1435.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP006716 Genomic DNA. Translation: BAE04152.1.
RefSeq	YP_252758.1. NC_007168.1.
3D structure databases
ProteinModelPortal	Q4L873.
ModBase	Search...
Protein-protein interaction databases
STRING	Q4L873.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTAT00000045251; EBSTAP00000043702; EBSTAG00000045248.
GeneID	3482141.
GenomeReviews	Gene locus SH0843 in contig AP006716_GR.
KEGG	sha:SH0843.
NMPDR	fig|279808.3.peg.856.
PATRIC	19617704. VBIStaHae67511_0828.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0698.
GeneTree	EBGT00050000024803.
HOGENOM	HBG636953.
OMA	ETHHANQ.
PhylomeDB	Q4L873.
ProtClustDB	PRK08622.
Enzyme and pathway databases
BioCyc	SHAE279808:SH0843-MONOMER.
Family and domain databases
HAMAP	MF_01556. LacB. [Tree]
InterPro	IPR004784. LacB. IPR003500. Rib/Gal_isomrase. [Graphical view]
Gene3D	G3DSA:3.40.1400.10. Rib/Gal_isomrase. 1 hit.
KO	K01819.
Pfam	PF02502. LacAB_rpiB. 1 hit. [Graphical view]
PIRSF	PIRSF005384. RpiB_LacA_B. 1 hit.
SUPFAM	SSF89623. Rib/Gal_isomrase. 1 hit.
TIGRFAMs	TIGR01119. LacB. 1 hit. TIGR00689. RpiB_lacA_lacB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

LACB_STAHJ

Accession

Primary (citable) accession number: Q4L873

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 10, 2006
Last sequence update:	August 2, 2005
Last modified:	January 25, 2012
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program