Reviewed, UniProtKB/Swiss-Prot Q4L803 (ALD1_STAHJ)

Names and origin

Protein names

Recommended name:
    Putative aldehyde dehydrogenase SH0913
    EC=1.2.1.3

Gene names

Ordered Locus Names:

SH0913

Organism

Staphylococcus haemolyticus (strain JCSC1435) [Complete proteome] [HAMAP]

Taxonomic identifier

279808 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	475 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	An aldehyde + NAD+ + H2O = an acid + NADH.
Sequence similarities	Belongs to the aldehyde dehydrogenase family.

Ontologies

Keywords
Ligand	NAD
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	aldehyde dehydrogenase (NAD) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 475	475	Putative aldehyde dehydrogenase SH0913		PRO_0000293563
Regions
	Nucleotide binding	201 – 207	7	NAD By similarity
Sites
	Active site	245	1	By similarity
	Active site	279	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q4L803-1 [UniParc]. Last modified July 10, 2007. Version 2. Checksum: 8B75A796F9CDCCE7	FASTA	475	51,949
	10 20 30 40 50 60 MRNYTQQYIN GEWIDSDSNE TIEVINPATE EVIGKVAKGN SNDVEKAVEA ANNVYLEFRH 70 80 90 100 110 120 SSVKERKELL DKIVEEYKNR KQDIIEAITD ELGAPLTLSE NVHYQMGLNH FEEASRALDS 130 140 150 160 170 180 FEFEERRGDA LVTKEAIGVS GLVTPWNFPT NQTSLKLAAA FAAGSPVVLK PSEETPFAAV 190 200 210 220 230 240 ILAEIFDKVG VPKGVFNLVN GDGEGVGNPL SEHPKVRMMS FTGSGRTGSK IMEKASKDFK 250 260 270 280 290 300 KVSLELGGKS PYIVLDDVDV KEAAKATTGK VVNNTGQVCT AGTRILIPES KKEDFLTALK 310 320 330 340 350 360 EEFSKVKVGD PREEGTQVGP IISKKQFDTV QSYIDKGIEE GAELFYGGPG KPEGLNTGYF 370 380 390 400 410 420 ARPTIFINVD NDMTIAQEEI FGPVASVITY NNLDEAIKIA NDTKYGLAGY VIGKDKETLQ 430 440 450 460 470 KVARSIEAGR IEINEAGNQP DLPFGGYKQS GIGREWGDYG IEEFLEVKSI AGYFS

References

[1]

"Whole-genome sequencing of Staphylococcus haemolyticus uncovers the extreme plasticity of its genome and the evolution of human-colonizing staphylococcal species." Takeuchi F., Watanabe S., Baba T., Yuzawa H., Ito T., Morimoto Y., Kuroda M., Cui L., Takahashi M., Ankai A., Baba S., Fukui S., Lee J.C., Hiramatsu K. J. Bacteriol. 187:7292-7308(2005) [PubMed: 16237012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP006716 Genomic DNA. Translation: BAE04222.1. Different initiation.
RefSeq	YP_252828.1.
3D structure databases
HSSP	HSSP built from PDB template 2D4E based on UniProtKB Q5SJP9.
SMR	Q4L803. Positions 1-471.
ModBase	Search...
Protein-protein interaction databases
STRING	Q4L803.
Genome annotation databases
GeneID	3481610.
GenomeReviews	Gene locus SH0913 in contig AP006716_GR.
KEGG	sha:SH0913.
NMPDR	fig|279808.3.peg.1265.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1012.
HOGENOM	HBG752218.
OMA	QITINNA.
Enzyme and pathway databases
BioCyc	SHAE279808:SH0913-MONOMER.
Family and domain databases
InterPro	IPR016161. Ald_DH/histidinol_DH. IPR016160. Ald_DH_CS. IPR016162. Ald_DH_N. IPR015590. Aldehyde_DH. [Graphical view]
Gene3D	G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
PANTHER	PTHR11699. Aldehyde_dehyd. 1 hit.
Pfam	PF00171. Aldedh. 1 hit. [Graphical view]
PROSITE	PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit. PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ALD1_STAHJ

Accession

Primary (citable) accession number: Q4L803

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 10, 2007
Last sequence update:	July 10, 2007
Last modified:	January 19, 2010
This is version 33 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)