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Q4L7Z6

- PTPB_STAHJ

UniProt

Q4L7Z6 - PTPB_STAHJ

Protein

Low molecular weight protein-tyrosine-phosphatase PtpB

Gene

ptpB

Organism
Staphylococcus haemolyticus (strain JCSC1435)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 58 (01 Oct 2014)
      Sequence version 1 (02 Aug 2005)
      Previous versions | rss
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    Functioni

    Dephosphorylates the phosphotyrosine-containing proteins.By similarity

    Catalytic activityi

    Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei7 – 71NucleophileBy similarity
    Active sitei13 – 131By similarity
    Active sitei111 – 1111Proton donorBy similarity

    GO - Molecular functioni

    1. protein tyrosine phosphatase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Enzyme and pathway databases

    BioCyciSHAE279808:GJX7-931-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Low molecular weight protein-tyrosine-phosphatase PtpB (EC:3.1.3.48)
    Alternative name(s):
    Phosphotyrosine phosphatase B
    Short name:
    PTPase B
    Gene namesi
    Name:ptpB
    Ordered Locus Names:SH0920
    OrganismiStaphylococcus haemolyticus (strain JCSC1435)
    Taxonomic identifieri279808 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
    ProteomesiUP000000543: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 138138Low molecular weight protein-tyrosine-phosphatase PtpBPRO_0000300682Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi279808.SH0920.

    Structurei

    3D structure databases

    ProteinModelPortaliQ4L7Z6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0394.
    HOGENOMiHOG000273091.
    KOiK01104.
    OMAiPMAMALL.
    OrthoDBiEOG6MH5JB.

    Family and domain databases

    InterProiIPR023485. Ptyr_pPase_SF.
    IPR000106. Tyr_phospatase/Ars_reductase.
    IPR017867. Tyr_phospatase_low_mol_wt.
    [Graphical view]
    PANTHERiPTHR11717. PTHR11717. 1 hit.
    PfamiPF01451. LMWPc. 1 hit.
    [Graphical view]
    PRINTSiPR00719. LMWPTPASE.
    SMARTiSM00226. LMWPc. 1 hit.
    [Graphical view]
    SUPFAMiSSF52788. SSF52788. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q4L7Z6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRITFVCTGN TCRSPIAESI AKKMLVDDTI NSRGLFAIDG QSVSPESLEV    50
    IMEHNLPEPT VAKQFSEKDL NSDLILTMTD MHKQQLVSHY GDNGRIYQLS 100
    EYVGEIGDIV DPFGGSIDTY RQTFEQLLYL IGKLRTNS 138
    Length:138
    Mass (Da):15,463
    Last modified:August 2, 2005 - v1
    Checksum:i0AF4C3E3F8D6BC25
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP006716 Genomic DNA. Translation: BAE04229.1.
    RefSeqiWP_011275231.1. NC_007168.1.
    YP_252835.1. NC_007168.1.

    Genome annotation databases

    EnsemblBacteriaiBAE04229; BAE04229; SH0920.
    GeneIDi3481613.
    KEGGisha:SH0920.
    PATRICi19617881. VBIStaHae67511_0907.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP006716 Genomic DNA. Translation: BAE04229.1 .
    RefSeqi WP_011275231.1. NC_007168.1.
    YP_252835.1. NC_007168.1.

    3D structure databases

    ProteinModelPortali Q4L7Z6.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 279808.SH0920.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAE04229 ; BAE04229 ; SH0920 .
    GeneIDi 3481613.
    KEGGi sha:SH0920.
    PATRICi 19617881. VBIStaHae67511_0907.

    Phylogenomic databases

    eggNOGi COG0394.
    HOGENOMi HOG000273091.
    KOi K01104.
    OMAi PMAMALL.
    OrthoDBi EOG6MH5JB.

    Enzyme and pathway databases

    BioCyci SHAE279808:GJX7-931-MONOMER.

    Family and domain databases

    InterProi IPR023485. Ptyr_pPase_SF.
    IPR000106. Tyr_phospatase/Ars_reductase.
    IPR017867. Tyr_phospatase_low_mol_wt.
    [Graphical view ]
    PANTHERi PTHR11717. PTHR11717. 1 hit.
    Pfami PF01451. LMWPc. 1 hit.
    [Graphical view ]
    PRINTSi PR00719. LMWPTPASE.
    SMARTi SM00226. LMWPc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52788. SSF52788. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Whole-genome sequencing of Staphylococcus haemolyticus uncovers the extreme plasticity of its genome and the evolution of human-colonizing staphylococcal species."
      Takeuchi F., Watanabe S., Baba T., Yuzawa H., Ito T., Morimoto Y., Kuroda M., Cui L., Takahashi M., Ankai A., Baba S., Fukui S., Lee J.C., Hiramatsu K.
      J. Bacteriol. 187:7292-7308(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: JCSC1435.

    Entry informationi

    Entry nameiPTPB_STAHJ
    AccessioniPrimary (citable) accession number: Q4L7Z6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 11, 2007
    Last sequence update: August 2, 2005
    Last modified: October 1, 2014
    This is version 58 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3