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Q4L7Z6

- PTPB_STAHJ

UniProt

Q4L7Z6 - PTPB_STAHJ

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Protein

Low molecular weight protein-tyrosine-phosphatase PtpB

Gene

ptpB

Organism
Staphylococcus haemolyticus (strain JCSC1435)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Dephosphorylates the phosphotyrosine-containing proteins.By similarity

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei7 – 71NucleophileBy similarity
Active sitei13 – 131By similarity
Active sitei111 – 1111Proton donorBy similarity

GO - Molecular functioni

  1. protein tyrosine phosphatase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Enzyme and pathway databases

BioCyciSHAE279808:GJX7-931-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Low molecular weight protein-tyrosine-phosphatase PtpB (EC:3.1.3.48)
Alternative name(s):
Phosphotyrosine phosphatase B
Short name:
PTPase B
Gene namesi
Name:ptpB
Ordered Locus Names:SH0920
OrganismiStaphylococcus haemolyticus (strain JCSC1435)
Taxonomic identifieri279808 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
ProteomesiUP000000543: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 138138Low molecular weight protein-tyrosine-phosphatase PtpBPRO_0000300682Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi279808.SH0920.

Structurei

3D structure databases

ProteinModelPortaliQ4L7Z6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0394.
HOGENOMiHOG000273091.
KOiK01104.
OMAiPMAMALL.
OrthoDBiEOG6MH5JB.

Family and domain databases

InterProiIPR023485. Ptyr_pPase_SF.
IPR000106. Tyr_phospatase/Ars_reductase.
IPR017867. Tyr_phospatase_low_mol_wt.
[Graphical view]
PANTHERiPTHR11717:SF14. PTHR11717:SF14. 1 hit.
PfamiPF01451. LMWPc. 1 hit.
[Graphical view]
PRINTSiPR00719. LMWPTPASE.
SMARTiSM00226. LMWPc. 1 hit.
[Graphical view]
SUPFAMiSSF52788. SSF52788. 1 hit.

Sequencei

Sequence statusi: Complete.

Q4L7Z6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRITFVCTGN TCRSPIAESI AKKMLVDDTI NSRGLFAIDG QSVSPESLEV
60 70 80 90 100
IMEHNLPEPT VAKQFSEKDL NSDLILTMTD MHKQQLVSHY GDNGRIYQLS
110 120 130
EYVGEIGDIV DPFGGSIDTY RQTFEQLLYL IGKLRTNS
Length:138
Mass (Da):15,463
Last modified:August 2, 2005 - v1
Checksum:i0AF4C3E3F8D6BC25
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP006716 Genomic DNA. Translation: BAE04229.1.
RefSeqiYP_252835.1. NC_007168.1.

Genome annotation databases

EnsemblBacteriaiBAE04229; BAE04229; SH0920.
GeneIDi3481613.
KEGGisha:SH0920.
PATRICi19617881. VBIStaHae67511_0907.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP006716 Genomic DNA. Translation: BAE04229.1 .
RefSeqi YP_252835.1. NC_007168.1.

3D structure databases

ProteinModelPortali Q4L7Z6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 279808.SH0920.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAE04229 ; BAE04229 ; SH0920 .
GeneIDi 3481613.
KEGGi sha:SH0920.
PATRICi 19617881. VBIStaHae67511_0907.

Phylogenomic databases

eggNOGi COG0394.
HOGENOMi HOG000273091.
KOi K01104.
OMAi PMAMALL.
OrthoDBi EOG6MH5JB.

Enzyme and pathway databases

BioCyci SHAE279808:GJX7-931-MONOMER.

Family and domain databases

InterProi IPR023485. Ptyr_pPase_SF.
IPR000106. Tyr_phospatase/Ars_reductase.
IPR017867. Tyr_phospatase_low_mol_wt.
[Graphical view ]
PANTHERi PTHR11717:SF14. PTHR11717:SF14. 1 hit.
Pfami PF01451. LMWPc. 1 hit.
[Graphical view ]
PRINTSi PR00719. LMWPTPASE.
SMARTi SM00226. LMWPc. 1 hit.
[Graphical view ]
SUPFAMi SSF52788. SSF52788. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Whole-genome sequencing of Staphylococcus haemolyticus uncovers the extreme plasticity of its genome and the evolution of human-colonizing staphylococcal species."
    Takeuchi F., Watanabe S., Baba T., Yuzawa H., Ito T., Morimoto Y., Kuroda M., Cui L., Takahashi M., Ankai A., Baba S., Fukui S., Lee J.C., Hiramatsu K.
    J. Bacteriol. 187:7292-7308(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JCSC1435.

Entry informationi

Entry nameiPTPB_STAHJ
AccessioniPrimary (citable) accession number: Q4L7Z6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: August 2, 2005
Last modified: October 29, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3