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Q4L7Z6 (PTPB_STAHJ) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Low molecular weight protein-tyrosine-phosphatase PtpB

EC=3.1.3.48
Alternative name(s):
Phosphotyrosine phosphatase B
Short name=PTPase B
Gene names
Name:ptpB
Ordered Locus Names:SH0920
OrganismStaphylococcus haemolyticus (strain JCSC1435) [Complete proteome] [HAMAP]
Taxonomic identifier279808 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesStaphylococcus

Protein attributes

Sequence length138 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Dephosphorylates the phosphotyrosine-containing proteins By similarity.

Catalytic activity

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Sequence similarities

Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

Ontologies

Keywords
   Molecular functionHydrolase
Protein phosphatase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular_functionprotein tyrosine phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 138138Low molecular weight protein-tyrosine-phosphatase PtpB
PRO_0000300682

Sites

Active site71Nucleophile By similarity
Active site131 By similarity
Active site1111Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
Q4L7Z6 [UniParc].

Last modified August 2, 2005. Version 1.
Checksum: 0AF4C3E3F8D6BC25

FASTA13815,463
        10         20         30         40         50         60 
MRITFVCTGN TCRSPIAESI AKKMLVDDTI NSRGLFAIDG QSVSPESLEV IMEHNLPEPT 

        70         80         90        100        110        120 
VAKQFSEKDL NSDLILTMTD MHKQQLVSHY GDNGRIYQLS EYVGEIGDIV DPFGGSIDTY 

       130 
RQTFEQLLYL IGKLRTNS 

« Hide

References

[1]"Whole-genome sequencing of Staphylococcus haemolyticus uncovers the extreme plasticity of its genome and the evolution of human-colonizing staphylococcal species."
Takeuchi F., Watanabe S., Baba T., Yuzawa H., Ito T., Morimoto Y., Kuroda M., Cui L., Takahashi M., Ankai A., Baba S., Fukui S., Lee J.C., Hiramatsu K.
J. Bacteriol. 187:7292-7308(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JCSC1435.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP006716 Genomic DNA. Translation: BAE04229.1.
RefSeqYP_252835.1. NC_007168.1.

3D structure databases

ProteinModelPortalQ4L7Z6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING279808.SH0920.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAE04229; BAE04229; SH0920.
GeneID3481613.
KEGGsha:SH0920.
PATRIC19617881. VBIStaHae67511_0907.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0394.
HOGENOMHOG000273091.
KOK01104.
OMAPMAMALL.
OrthoDBEOG6MH5JB.
ProtClustDBCLSK2462322.

Enzyme and pathway databases

BioCycSHAE279808:GJX7-931-MONOMER.

Family and domain databases

InterProIPR023485. Ptyr_pPase_SF.
IPR000106. Tyr_phospatase/Ars_reductase.
IPR017867. Tyr_phospatase_low_mol_wt.
[Graphical view]
PANTHERPTHR11717. PTHR11717. 1 hit.
PfamPF01451. LMWPc. 1 hit.
[Graphical view]
PRINTSPR00719. LMWPTPASE.
SMARTSM00226. LMWPc. 1 hit.
[Graphical view]
SUPFAMSSF52788. SSF52788. 1 hit.
ProtoNetSearch...

Entry information

Entry namePTPB_STAHJ
AccessionPrimary (citable) accession number: Q4L7Z6
Entry history
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: August 2, 2005
Last modified: April 16, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families