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Q4L7V5 (Q4L7V5_STAHJ) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Alanine racemase 1 HAMAP MF_01201
EC=5.1.1.1 HAMAP MF_01201
Gene names
Name:alr1 HAMAP MF_01201 EMBL BAE04270.1
Ordered Locus Names:SH0961
OrganismStaphylococcus haemolyticus (strain JCSC1435) [Complete proteome] [HAMAP]
Taxonomic identifier279808 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length382 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Provides the D-alanine required for cell wall biosynthesis By similarity. HAMAP MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP MF_01201

Cofactor

Pyridoxal phosphate By similarity. HAMAP MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP MF_01201

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site391Proton acceptor; specific for D-alanine By similarity HAMAP MF_01201
Active site2651Proton acceptor; specific for L-alanine By similarity HAMAP MF_01201

Amino acid modifications

Modified residue391N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_01201

Sequences

Sequence LengthMass (Da)Tools
Q4L7V5 [UniParc].

Last modified August 2, 2005. Version 1.
Checksum: 9EF9081F6941FAF2

FASTA38242,894
        10         20         30         40         50         60 
MSDKFYRSTY LNVDLSAILN NYNTVRTLHS DKTVIPVVKA NSYGLGSVKI AQHLMKNGAD 

        70         80         90        100        110        120 
FFAVATLDEA IELRMHGINA QILILGVIPL EDINKAIQHR VALTVPSLQW LQHAIELISD 

       130        140        150        160        170        180 
DNEKNLWLHV KLDTGMGRLG IKSLEEYKEV IDLIQSHPHL VFEGVYTHFA NADEPGDLMD 

       190        200        210        220        230        240 
HQYEQFETLV TQAEKPKFIH SQNSAGSLLR NFELCNAVRL GISLYGYYPS AYVKEKVETE 

       250        260        270        280        290        300 
LQPSAQLLTQ VVQTKYLKVG ESVSYGSTFT ATEDIKIAIL PIGYADGYLR SMQGAFVNVK 

       310        320        330        340        350        360 
GHQCEVIGRV CMDQMIIKVP DDVKEGDSVT LLDNAYDSPQ SAETLAQKQD TISYEVLCNL 

       370        380 
GRRLPRIYQV DDEMHVTNEL LK

« Hide

References

[1]"Whole-genome sequencing of Staphylococcus haemolyticus uncovers the extreme plasticity of its genome and the evolution of human-colonizing staphylococcal species."
Takeuchi F., Watanabe S., Baba T., Yuzawa H., Ito T., Morimoto Y., Kuroda M., Cui L., Takahashi M., Ankai A., Baba S., Fukui S., Lee J.C., Hiramatsu K.
J. Bacteriol. 187:7292-7308(2005) [PubMed: 16237012] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP006716 Genomic DNA. Translation: BAE04270.1.
RefSeqYP_252876.1. NC_007168.1.

3D structure databases

ProteinModelPortalQ4L7V5.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ4L7V5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBSTAT00000044918; EBSTAP00000043369; EBSTAG00000044916.
GeneID3482410.
GenomeReviewsGene locus SH0961 in contig AP006716_GR.
KEGGsha:SH0961.
NMPDRfig|279808.3.peg.1313.
PATRIC19617963. VBIStaHae67511_0948.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0787.
GeneTreeEBGT00050000023673.
HOGENOMHBG712172.
OMANWQIKAL.
PhylomeDBQ4L7V5.
ProtClustDBCLSK885747.

Enzyme and pathway databases

BioCycSHAE279808:SH0961-MONOMER.

Family and domain databases

HAMAPMF_01201. Ala_racemase.
[Tree]
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
[Graphical view]
Gene3DG3DSA:2.40.37.10. Ala_racemase/Decarboxylase_C. 1 hit.
KOK01775.
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMsTIGR00492. Alr. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ4L7V5_STAHJ
AccessionPrimary (citable) accession number: Q4L7V5
Entry history
Integrated into UniProtKB/TrEMBL: August 2, 2005
Last sequence update: August 2, 2005
Last modified: January 25, 2012
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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