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Protein

Low molecular weight protein-tyrosine-phosphatase PtpA

Gene

ptpA

Organism
Staphylococcus haemolyticus (strain JCSC1435)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Dephosphorylates the phosphotyrosine-containing proteins.By similarity

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei8NucleophileBy similarity1
Active sitei14By similarity1
Active sitei120Proton donorBy similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphatase

Names & Taxonomyi

Protein namesi
Recommended name:
Low molecular weight protein-tyrosine-phosphatase PtpA (EC:3.1.3.48)
Alternative name(s):
Phosphotyrosine phosphatase A
Short name:
PTPase A
Gene namesi
Name:ptpA
Ordered Locus Names:SH1075
OrganismiStaphylococcus haemolyticus (strain JCSC1435)
Taxonomic identifieri279808 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000000543 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003006681 – 154Low molecular weight protein-tyrosine-phosphatase PtpAAdd BLAST154

Interactioni

Protein-protein interaction databases

STRINGi279808.SH1075.

Structurei

3D structure databases

ProteinModelPortaliQ4L7J1.
SMRiQ4L7J1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4107ZCW. Bacteria.
COG0394. LUCA.
HOGENOMiHOG000273094.
KOiK01104.
OMAiAGTGSWH.
OrthoDBiPOG091H07J9.

Family and domain databases

InterProiView protein in InterPro
IPR023485. Ptyr_pPase_SF.
IPR017867. Tyr_phospatase_low_mol_wt.
PfamiView protein in Pfam
PF01451. LMWPc. 1 hit.
PRINTSiPR00719. LMWPTPASE.
SMARTiView protein in SMART
SM00226. LMWPc. 1 hit.
SUPFAMiSSF52788. SSF52788. 1 hit.

Sequencei

Sequence statusi: Complete.

Q4L7J1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVDVAFVCLG NICRSPMAEA IMRQRLIDRN ISGVNVYSKG TGKWNLGEPP
60 70 80 90 100
HEGTQDILNR HNIPFDGMIS ELFESSDDFD YIIAMDQSNV DNIQNINPNI
110 120 130 140 150
KGKLFKLLEF SNMEESDVPD PYYTNNFEGV YEMVQSSCDN LIDFIVKDAN

LKEG
Length:154
Mass (Da):17,450
Last modified:August 2, 2005 - v1
Checksum:i2B73F64676E5D9AE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006716 Genomic DNA. Translation: BAE04384.1.
RefSeqiWP_011275379.1. NC_007168.1.

Genome annotation databases

EnsemblBacteriaiBAE04384; BAE04384; SH1075.
GeneIDi24245803.
KEGGisha:SH1075.

Similar proteinsi

Entry informationi

Entry nameiPTPA_STAHJ
AccessioniPrimary (citable) accession number: Q4L7J1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: August 2, 2005
Last modified: August 30, 2017
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families