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Q4L6M3 (EX7S_STAHJ) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Exodeoxyribonuclease 7 small subunit

EC=3.1.11.6
Alternative name(s):
Exodeoxyribonuclease VII small subunit
Short name=Exonuclease VII small subunit
Gene names
Name:xseB
Ordered Locus Names:SH1393
OrganismStaphylococcus haemolyticus (strain JCSC1435) [Complete proteome] [HAMAP]
Taxonomic identifier279808 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesStaphylococcus

Protein attributes

Sequence length76 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides By similarity. HAMAP-Rule MF_00337

Catalytic activity

Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates. HAMAP-Rule MF_00337

Subunit structure

Heterooligomer composed of large and small subunits By similarity.

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00337.

Sequence similarities

Belongs to the XseB family.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionExonuclease
Hydrolase
Nuclease
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

exodeoxyribonuclease VII complex

Inferred from electronic annotation. Source: InterPro

   Molecular_functionexodeoxyribonuclease VII activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 7676Exodeoxyribonuclease 7 small subunit HAMAP-Rule MF_00337
PRO_0000303753

Sequences

Sequence LengthMass (Da)Tools
Q4L6M3 [UniParc].

Last modified August 2, 2005. Version 1.
Checksum: 8F5F0E30D9367C84

FASTA768,770
        10         20         30         40         50         60 
MSKDQQSFEE MMQELENIVQ KLDNETVSLE ESLELYQRGM KLSATCDATL KDAEKKVNQL 

        70 
IKDEAEDEEN GKEVNE 

« Hide

References

[1]"Whole-genome sequencing of Staphylococcus haemolyticus uncovers the extreme plasticity of its genome and the evolution of human-colonizing staphylococcal species."
Takeuchi F., Watanabe S., Baba T., Yuzawa H., Ito T., Morimoto Y., Kuroda M., Cui L., Takahashi M., Ankai A., Baba S., Fukui S., Lee J.C., Hiramatsu K.
J. Bacteriol. 187:7292-7308(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JCSC1435.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP006716 Genomic DNA. Translation: BAE04702.1.
RefSeqYP_253308.1. NC_007168.1.

3D structure databases

ProteinModelPortalQ4L6M3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING279808.SH1393.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAE04702; BAE04702; SH1393.
GeneID3483408.
KEGGsha:SH1393.
PATRIC19618899. VBIStaHae67511_1373.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1722.
HOGENOMHOG000228798.
KOK03602.
OMACEELLRT.
OrthoDBEOG69KV31.
ProtClustDBPRK14068.

Enzyme and pathway databases

BioCycSHAE279808:GJX7-1447-MONOMER.

Family and domain databases

Gene3D1.10.287.1040. 1 hit.
HAMAPMF_00337. Exonuc_7_S.
InterProIPR003761. Exonuc_VII_S.
[Graphical view]
PfamPF02609. Exonuc_VII_S. 1 hit.
[Graphical view]
PIRSFPIRSF006488. Exonuc_VII_S. 1 hit.
ProDomPD028235. Exonuc_VII_S. 1 hit.
[Graphical view] [Entries sharing at least one domain]
TIGRFAMsTIGR01280. xseB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameEX7S_STAHJ
AccessionPrimary (citable) accession number: Q4L6M3
Entry history
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: August 2, 2005
Last modified: April 16, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families