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Protein

Peptide methionine sulfoxide reductase MsrB

Gene

msrB

Organism
Staphylococcus haemolyticus (strain JCSC1435)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei114NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Peptide methionine sulfoxide reductase MsrBUniRule annotation (EC:1.8.4.12UniRule annotation)
Alternative name(s):
Peptide-methionine (R)-S-oxide reductaseUniRule annotation
Gene namesi
Name:msrBUniRule annotation
Ordered Locus Names:SH1483
OrganismiStaphylococcus haemolyticus (strain JCSC1435)
Taxonomic identifieri279808 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000000543 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001403031 – 142Peptide methionine sulfoxide reductase MsrBAdd BLAST142

Interactioni

Protein-protein interaction databases

STRINGi279808.SH1483.

Structurei

3D structure databases

ProteinModelPortaliQ4L6D3.
SMRiQ4L6D3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 125MsrBPROSITE-ProRule annotationAdd BLAST124

Sequence similaritiesi

Belongs to the MsrB Met sulfoxide reductase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105E0X. Bacteria.
COG0229. LUCA.
HOGENOMiHOG000243425.
KOiK07305.
OMAiYKASHKF.
OrthoDBiPOG091H064P.

Family and domain databases

HAMAPiMF_01400. MsrB. 1 hit.
InterProiView protein in InterPro
IPR028427. Met_Sox_Rdtase.
IPR002579. Met_Sox_Rdtase_MsrB.
IPR011057. Mss4-like.
PANTHERiPTHR10173. PTHR10173. 1 hit.
PfamiView protein in Pfam
PF01641. SelR. 1 hit.
SUPFAMiSSF51316. SSF51316. 1 hit.
TIGRFAMsiTIGR00357. TIGR00357. 1 hit.
PROSITEiView protein in PROSITE
PS51790. MSRB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q4L6D3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIKKDKNELN EMEYLVTQEN GTEPPFQNEY WNHFDKGIYV DKISGKPLFT
60 70 80 90 100
SEEKFESNCG WPSFSKSIDD DEIIELVDKT FGMIRTEVRS EDANSHLGHV
110 120 130 140
FNDGPKESGG LRYCINSAAI QFIPYDKLEE LGYGDLIPHF EK
Length:142
Mass (Da):16,377
Last modified:August 2, 2005 - v1
Checksum:i2138EB898A8E43A7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006716 Genomic DNA. Translation: BAE04792.1.
RefSeqiWP_011275778.1. NC_007168.1.

Genome annotation databases

EnsemblBacteriaiBAE04792; BAE04792; SH1483.
GeneIDi24247198.
KEGGisha:SH1483.

Similar proteinsi

Entry informationi

Entry nameiMSRB_STAHJ
AccessioniPrimary (citable) accession number: Q4L6D3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: August 2, 2005
Last modified: August 30, 2017
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families