Q4L668 (Q4L668_STAHJ) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrA 3 HAMAP MF_01401
Short name=Protein-methionine-S-oxide reductase 3 HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401

Alternative name(s):
Peptide-methionine (S)-S-oxide reductase 3 HAMAP MF_01401

Gene names

Name:	msrA EMBL BAE04857.1
Synonyms:	msrA3 HAMAP MF_01401
Ordered Locus Names:	SH1548

Organism

Staphylococcus haemolyticus (strain JCSC1435) [Complete proteome] [HAMAP]

Taxonomic identifier

279808 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	168 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401
Catalytic activity	L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569 Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569
Sequence similarities	Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Ontologies

Keywords
Molecular function	Oxidoreductase HAMAP MF_01401 SAAS SAAS002569
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein modification process Inferred from electronic annotation. Source: HAMAP
Molecular function	peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	12	1	By similarity HAMAP MF_01401

Sequences

	Sequence		Length	Mass (Da)
	Q4L668 [UniParc]. Last modified August 2, 2005. Version 1. Checksum: EE34BA7C0B56B009	FASTA	168	19,464
	10 20 30 40 50 60 MNINTAYFAG GCFWCMTKPF DQFDGIETVT SGYMGGSTHN PTYEDVKSGT TGHYETVKIE 70 80 90 100 110 120 YDVALFSYNK LLEVFFSVID PIDDGGQFQD RGSQYRTAIF YTNEDQKRLA EQYVHQLEQT 130 140 150 160 IHSEKAIATK ILPASTFYKA EEYHQDFYKK NPERYAQEQQ DRANYKSN

References

[1]

"Whole-genome sequencing of Staphylococcus haemolyticus uncovers the extreme plasticity of its genome and the evolution of human-colonizing staphylococcal species." Takeuchi F., Watanabe S., Baba T., Yuzawa H., Ito T., Morimoto Y., Kuroda M., Cui L., Takahashi M., Ankai A., Baba S., Fukui S., Lee J.C., Hiramatsu K. J. Bacteriol. 187:7292-7308(2005) [PubMed: 16237012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP006716 Genomic DNA. Translation: BAE04857.1.
RefSeq	YP_253463.1. NC_007168.1.
3D structure databases
ProteinModelPortal	Q4L668.
ModBase	Search...
Protein-protein interaction databases
STRING	Q4L668.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTAT00000045203; EBSTAP00000043654; EBSTAG00000045200.
GeneID	3482063.
GenomeReviews	Gene locus SH1548 in contig AP006716_GR.
KEGG	sha:SH1548.
NMPDR	fig|279808.3.peg.2361.
PATRIC	19619203. VBIStaHae67511_1525.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0225.
GeneTree	EBGT00050000024265.
HOGENOM	HBG748152.
OMA	KIEYDVA.
PhylomeDB	Q4L668.
ProtClustDB	PRK14054.
Enzyme and pathway databases
BioCyc	SHAE279808:SH1548-MONOMER.
Family and domain databases
HAMAP	MF_01401. MsrA. [Tree]
InterPro	IPR002569. Peptide_Met_Sox_Rdtase_MsrA. [Graphical view]
Gene3D	G3DSA:3.30.1060.10. MsrA. 1 hit.
KO	K07304.
Pfam	PF01625. PMSR. 1 hit. [Graphical view]
SUPFAM	SSF55068. MsrA. 1 hit.
TIGRFAMs	TIGR00401. MsrA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q4L668_STAHJ

Accession

Primary (citable) accession number: Q4L668

Entry history

Integrated into UniProtKB/TrEMBL:	August 2, 2005
Last sequence update:	August 2, 2005
Last modified:	December 14, 2011
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)