Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q4L3C1

- SLE1_STAHJ

UniProt

Q4L3C1 - SLE1_STAHJ

Protein

N-acetylmuramoyl-L-alanine amidase sle1

Gene

sle1

Organism
Staphylococcus haemolyticus (strain JCSC1435)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 1 (02 Aug 2005)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Peptidoglycan hydrolase involved in the splitting of the septum during cell division.By similarity

    Catalytic activityi

    Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.

    GO - Molecular functioni

    1. N-acetylmuramoyl-L-alanine amidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. barrier septum assembly Source: UniProtKB-KW
    2. cytolysis Source: UniProtKB-KW
    3. defense response to bacterium Source: UniProtKB-KW
    4. pathogenesis Source: UniProtKB-KW

    Keywords - Molecular functioni

    Antimicrobial, Bacteriolytic enzyme, Hydrolase

    Keywords - Biological processi

    Cell cycle, Cell division, Cell wall biogenesis/degradation, Septation, Virulence

    Enzyme and pathway databases

    BioCyciSHAE279808:GJX7-2622-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    N-acetylmuramoyl-L-alanine amidase sle1 (EC:3.5.1.28)
    Gene namesi
    Name:sle1
    Synonyms:aaa
    Ordered Locus Names:SH2547
    OrganismiStaphylococcus haemolyticus (strain JCSC1435)
    Taxonomic identifieri279808 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
    ProteomesiUP000000543: Chromosome

    Subcellular locationi

    Secreted By similarity. Cell surface By similarity

    GO - Cellular componenti

    1. cell surface Source: UniProtKB-SubCell
    2. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2626Sequence AnalysisAdd
    BLAST
    Chaini27 – 329303N-acetylmuramoyl-L-alanine amidase sle1PRO_0000231629Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi279808.SH2547.

    Structurei

    3D structure databases

    ProteinModelPortaliQ4L3C1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Repeati30 – 7243LysM 1Add
    BLAST
    Repeati90 – 13243LysM 2Add
    BLAST
    Repeati154 – 19643LysM 3Add
    BLAST
    Domaini205 – 329125Peptidase C51PROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 3 LysM repeats.Curated
    Contains 1 peptidase C51 domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat, Signal

    Phylogenomic databases

    eggNOGiCOG3942.
    HOGENOMiHOG000279823.
    OMAiEMNYSAS.
    OrthoDBiEOG6GTZPF.

    Family and domain databases

    Gene3Di3.10.350.10. 3 hits.
    InterProiIPR007921. CHAP_dom.
    IPR018392. LysM_dom.
    [Graphical view]
    PfamiPF05257. CHAP. 1 hit.
    PF01476. LysM. 3 hits.
    [Graphical view]
    SMARTiSM00257. LysM. 3 hits.
    [Graphical view]
    SUPFAMiSSF54106. SSF54106. 3 hits.
    PROSITEiPS50911. CHAP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q4L3C1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNKKILATAV LGTGALSTLF AHQAEASTTH TVRSGESLWS ISHHYGITVS    50
    KLKSLNGLSS NLIFPNQVLK VSGSSNYSSR SNYGNSSSTY TVRAGDSLSS 100
    IASRYGTTYR HIMNLNGLNS FLIFPGQQLK VSGSVSSNSH SSYNSNSGGS 150
    SSTYTVRYGD SLSSIASRYG TTYQHIMRLN GLNNFFIYPG QKLRVSGSAS 200
    SNTYSTRSAQ STYYSSPVFN HRNLYDWGQC TWHVFNRRAA IGKGISTYWW 250
    NANNWDNAAA RDGYRIDGNP TVGSIAQSDA GYYGHVAFVE RVNSNGSILV 300
    SEMNFSASPG ILTYRTIPAY QVRNYKFIH 329
    Length:329
    Mass (Da):36,019
    Last modified:August 2, 2005 - v1
    Checksum:i8C1645D548459455
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP006716 Genomic DNA. Translation: BAE05856.1.
    RefSeqiYP_254462.1. NC_007168.1.

    Genome annotation databases

    EnsemblBacteriaiBAE05856; BAE05856; SH2547.
    GeneIDi3482633.
    KEGGisha:SH2547.
    PATRICi19621195. VBIStaHae67511_2500.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP006716 Genomic DNA. Translation: BAE05856.1 .
    RefSeqi YP_254462.1. NC_007168.1.

    3D structure databases

    ProteinModelPortali Q4L3C1.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 279808.SH2547.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAE05856 ; BAE05856 ; SH2547 .
    GeneIDi 3482633.
    KEGGi sha:SH2547.
    PATRICi 19621195. VBIStaHae67511_2500.

    Phylogenomic databases

    eggNOGi COG3942.
    HOGENOMi HOG000279823.
    OMAi EMNYSAS.
    OrthoDBi EOG6GTZPF.

    Enzyme and pathway databases

    BioCyci SHAE279808:GJX7-2622-MONOMER.

    Family and domain databases

    Gene3Di 3.10.350.10. 3 hits.
    InterProi IPR007921. CHAP_dom.
    IPR018392. LysM_dom.
    [Graphical view ]
    Pfami PF05257. CHAP. 1 hit.
    PF01476. LysM. 3 hits.
    [Graphical view ]
    SMARTi SM00257. LysM. 3 hits.
    [Graphical view ]
    SUPFAMi SSF54106. SSF54106. 3 hits.
    PROSITEi PS50911. CHAP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Whole-genome sequencing of Staphylococcus haemolyticus uncovers the extreme plasticity of its genome and the evolution of human-colonizing staphylococcal species."
      Takeuchi F., Watanabe S., Baba T., Yuzawa H., Ito T., Morimoto Y., Kuroda M., Cui L., Takahashi M., Ankai A., Baba S., Fukui S., Lee J.C., Hiramatsu K.
      J. Bacteriol. 187:7292-7308(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: JCSC1435.

    Entry informationi

    Entry nameiSLE1_STAHJ
    AccessioniPrimary (citable) accession number: Q4L3C1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 4, 2006
    Last sequence update: August 2, 2005
    Last modified: October 1, 2014
    This is version 61 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Peptidase families
      Classification of peptidase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3