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Protein

Uronate isomerase

Gene

uxaC

Organism
Staphylococcus haemolyticus (strain JCSC1435)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucuronate = D-fructuronate.UniRule annotation
D-galacturonate = D-tagaturonate.UniRule annotation

Pathwayi: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

BioCyciSHAE279808:GJX7-2723-MONOMER.
UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Uronate isomeraseUniRule annotation (EC:5.3.1.12UniRule annotation)
Alternative name(s):
Glucuronate isomeraseUniRule annotation
Uronic isomeraseUniRule annotation
Gene namesi
Name:uxaCUniRule annotation
Ordered Locus Names:SH2648
OrganismiStaphylococcus haemolyticus (strain JCSC1435)
Taxonomic identifieri279808 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000000543 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 467467Uronate isomerasePRO_1000044779Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi279808.SH2648.

Structurei

3D structure databases

ProteinModelPortaliQ4L320.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uronate isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
HOGENOMiHOG000224075.
KOiK01812.
OMAiMAWAKTV.
OrthoDBiEOG6J1D95.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.

Sequencei

Sequence statusi: Complete.

Q4L320-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFINEHFML NNETGKHLYH DFAKDMPIYD YHCHLDPKQI SDNVACDNIT
60 70 80 90 100
DLWLSGDHYK WRAMRAQGIE EQYITGDAAP LDKFKKWTET LENSVGNPLY
110 120 130 140 150
HWSQLELKMY FDIEDLLTSD NAEAIYHRAN DYLKQHHTTT QSLITDSNVN
160 170 180 190 200
LICTTDNPTD DLNYHDAIKA KDGFNTTVLP AFRPDDVFKV GDPAFTDLLQ
210 220 230 240 250
KLENLTHPIT TPSDFIEALY KRIQYFHDKG GRLADHGLEE MHFEAYTDQA
260 270 280 290 300
IQDIFKKALN HADISTYERF QFQSYMLNEL SKAYYERGWV MQIHFGAIRN
310 320 330 340 350
NNTKMFEKVG KDAGFDSIRD QDNLAYHLNA TLDMMEQEGH LPKTILYNLN
360 370 380 390 400
PIYNDIVGST IANFQTEPGI KSKVQHGAGW WFNDTKRGML RQMSSLADQG
410 420 430 440 450
LLMHFVGMLT DSRSFISYSR HDYFRRILSS FIGDLVEKGE IPNDDQLLKR
460
MIENICYNNA YNYFKLI
Length:467
Mass (Da):54,328
Last modified:August 2, 2005 - v1
Checksum:iD3DE78446DD3CE1A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006716 Genomic DNA. Translation: BAE05957.1.
RefSeqiWP_011276887.1. NC_007168.1.

Genome annotation databases

EnsemblBacteriaiBAE05957; BAE05957; SH2648.
GeneIDi24246857.
KEGGisha:SH2648.
PATRICi19621387. VBIStaHae67511_2596.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006716 Genomic DNA. Translation: BAE05957.1.
RefSeqiWP_011276887.1. NC_007168.1.

3D structure databases

ProteinModelPortaliQ4L320.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi279808.SH2648.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAE05957; BAE05957; SH2648.
GeneIDi24246857.
KEGGisha:SH2648.
PATRICi19621387. VBIStaHae67511_2596.

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
HOGENOMiHOG000224075.
KOiK01812.
OMAiMAWAKTV.
OrthoDBiEOG6J1D95.

Enzyme and pathway databases

UniPathwayiUPA00246.
BioCyciSHAE279808:GJX7-2723-MONOMER.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Whole-genome sequencing of Staphylococcus haemolyticus uncovers the extreme plasticity of its genome and the evolution of human-colonizing staphylococcal species."
    Takeuchi F., Watanabe S., Baba T., Yuzawa H., Ito T., Morimoto Y., Kuroda M., Cui L., Takahashi M., Ankai A., Baba S., Fukui S., Lee J.C., Hiramatsu K.
    J. Bacteriol. 187:7292-7308(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JCSC1435.

Entry informationi

Entry nameiUXAC_STAHJ
AccessioniPrimary (citable) accession number: Q4L320
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 2, 2005
Last modified: June 8, 2016
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.