Q4L320 (UXAC_STAHJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uronate isomerase
EC=5.3.1.12

Alternative name(s):
Glucuronate isomerase
Uronic isomerase

Gene names

Name:	uxaC
Ordered Locus Names:	SH2648

Organism

Staphylococcus haemolyticus (strain JCSC1435) [Complete proteome] [HAMAP]

Taxonomic identifier

279808 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	467 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-glucuronate = D-fructuronate. HAMAP MF_00675 D-galacturonate = D-tagaturonate. HAMAP MF_00675
Pathway	Carbohydrate metabolism; pentose and glucuronate interconversion. HAMAP MF_00675
Sequence similarities	Belongs to the uronate isomerase family.

Ontologies

Keywords
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glucuronate catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	glucuronate isomerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 467	467	Uronate isomerase HAMAP MF_00675		PRO_1000044779

Sequences

	Sequence		Length	Mass (Da)
	Q4L320 [UniParc]. Last modified August 2, 2005. Version 1. Checksum: D3DE78446DD3CE1A	FASTA	467	54,328
	10 20 30 40 50 60 MAFINEHFML NNETGKHLYH DFAKDMPIYD YHCHLDPKQI SDNVACDNIT DLWLSGDHYK 70 80 90 100 110 120 WRAMRAQGIE EQYITGDAAP LDKFKKWTET LENSVGNPLY HWSQLELKMY FDIEDLLTSD 130 140 150 160 170 180 NAEAIYHRAN DYLKQHHTTT QSLITDSNVN LICTTDNPTD DLNYHDAIKA KDGFNTTVLP 190 200 210 220 230 240 AFRPDDVFKV GDPAFTDLLQ KLENLTHPIT TPSDFIEALY KRIQYFHDKG GRLADHGLEE 250 260 270 280 290 300 MHFEAYTDQA IQDIFKKALN HADISTYERF QFQSYMLNEL SKAYYERGWV MQIHFGAIRN 310 320 330 340 350 360 NNTKMFEKVG KDAGFDSIRD QDNLAYHLNA TLDMMEQEGH LPKTILYNLN PIYNDIVGST 370 380 390 400 410 420 IANFQTEPGI KSKVQHGAGW WFNDTKRGML RQMSSLADQG LLMHFVGMLT DSRSFISYSR 430 440 450 460 HDYFRRILSS FIGDLVEKGE IPNDDQLLKR MIENICYNNA YNYFKLI

References

[1]

"Whole-genome sequencing of Staphylococcus haemolyticus uncovers the extreme plasticity of its genome and the evolution of human-colonizing staphylococcal species." Takeuchi F., Watanabe S., Baba T., Yuzawa H., Ito T., Morimoto Y., Kuroda M., Cui L., Takahashi M., Ankai A., Baba S., Fukui S., Lee J.C., Hiramatsu K. J. Bacteriol. 187:7292-7308(2005) [PubMed: 16237012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: JCSC1435.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP006716 Genomic DNA. Translation: BAE05957.1.
RefSeq	YP_254563.1. NC_007168.1.
3D structure databases
HSSP	HSSP built from PDB template 1J5S based on UniProtKB Q9WXR9.
ProteinModelPortal	Q4L320.
ModBase	Search...
Protein-protein interaction databases
STRING	Q4L320.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTAT00000044899; EBSTAP00000043350; EBSTAG00000044897.
GeneID	3482553.
GenomeReviews	Gene locus SH2648 in contig AP006716_GR.
KEGG	sha:SH2648.
NMPDR	fig|279808.3.peg.1468.
PATRIC	19621387. VBIStaHae67511_2596.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1904.
HOGENOM	HBG297087.
OMA	KAFARTL.
PhylomeDB	Q4L320.
ProtClustDB	PRK02925.
Enzyme and pathway databases
BioCyc	SHAE279808:SH2648-MONOMER.
Family and domain databases
HAMAP	MF_00675. UxaC. [Tree]
InterPro	IPR003766. Uronate_isomerase. IPR023177. Uronate_isomerase_dom2. [Graphical view]
Gene3D	G3DSA:1.10.2020.10. Uronate_isomerase_dom2. 1 hit.
KO	K01812.
Pfam	PF02614. UxaC. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

UXAC_STAHJ

Accession

Primary (citable) accession number: Q4L320

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	August 2, 2005
Last modified:	January 25, 2012
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program