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Protein

Ribonuclease P protein component

Gene

rnpA

Organism
Staphylococcus haemolyticus (strain JCSC1435)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonuclease, Hydrolase, Nuclease, RNA-binding
Biological processtRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein componentUniRule annotation (EC:3.1.26.5UniRule annotation)
Short name:
RNase P proteinUniRule annotation
Short name:
RNaseP proteinUniRule annotation
Alternative name(s):
Protein C5UniRule annotation
Gene namesi
Name:rnpAUniRule annotation
Ordered Locus Names:SH2677
OrganismiStaphylococcus haemolyticus (strain JCSC1435)
Taxonomic identifieri279808 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000000543 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000214731 – 114Ribonuclease P protein componentAdd BLAST114

Interactioni

Subunit structurei

Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.UniRule annotation

Protein-protein interaction databases

STRINGi279808.SH2677

Structurei

3D structure databases

ProteinModelPortaliQ4L2Z1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RnpA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105M7T Bacteria
COG0594 LUCA
HOGENOMiHOG000266301
KOiK03536
OMAiFEACIRR
OrthoDBiPOG091H01XK

Family and domain databases

Gene3Di3.30.230.101 hit
HAMAPiMF_00227 RNase_P, 1 hit
InterProiView protein in InterPro
IPR020568 Ribosomal_S5_D2-typ_fold
IPR014721 Ribosomal_S5_D2-typ_fold_subgr
IPR000100 RNase_P
IPR020539 RNase_P_CS
PANTHERiPTHR33992 PTHR33992, 1 hit
PfamiView protein in Pfam
PF00825 Ribonuclease_P, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD003629 Ribonuclease_P, 1 hit
SUPFAMiSSF54211 SSF54211, 1 hit
TIGRFAMsiTIGR00188 rnpA, 1 hit
PROSITEiView protein in PROSITE
PS00648 RIBONUCLEASE_P, 1 hit

Sequencei

Sequence statusi: Complete.

Q4L2Z1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKAYRIKKN TDFQTIYKRG KSVANRQFVV YTYNSNKDHF RLGISVSKKL
60 70 80 90 100
GNAVTRNRIK RAIRENFKIH KEDIIARDII VIARQPAKDM TTLEIQGSLE
110
HVLKIAKVFN KKIK
Length:114
Mass (Da):13,347
Last modified:August 2, 2005 - v1
Checksum:i9144A9D4BF8F574F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006716 Genomic DNA Translation: BAE05986.1
RefSeqiWP_011276916.1, NC_007168.1

Genome annotation databases

EnsemblBacteriaiBAE05986; BAE05986; SH2677
GeneIDi24248167
KEGGisha:SH2677

Similar proteinsi

Entry informationi

Entry nameiRNPA_STAHJ
AccessioniPrimary (citable) accession number: Q4L2Z1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 2, 2005
Last modified: April 25, 2018
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome