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Protein
Submitted name:

Splicing factor proline/glutamine rich (Polypyrimidine tract binding protein associated)

Gene

Sfpq

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRNA-bindingPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Splicing factor proline/glutamine rich (Polypyrimidine tract binding protein associated)Imported
Gene namesi
Name:SfpqImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi727923 Sfpq

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PRIDEiQ4KM71

PTM databases

iPTMnetiQ4KM71
PhosphoSitePlusiQ4KM71

Expressioni

Gene expression databases

GenevisibleiQ4KM71 RN

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliQ4KM71
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini289 – 361RRMInterPro annotationAdd BLAST73
Domaini363 – 444RRMInterPro annotationAdd BLAST82

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili490 – 521Sequence analysisAdd BLAST32
Coiled coili524 – 587Sequence analysisAdd BLAST64

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0115 Eukaryota
ENOG410XQA0 LUCA
HOGENOMiHOG000231095
HOVERGENiHBG009801
KOiK13219
PhylomeDBiQ4KM71

Family and domain databases

CDDicd12948 NOPS_PSF, 1 hit
cd12587 RRM1_PSF, 1 hit
Gene3Di3.30.70.330, 2 hits
InterProiView protein in InterPro
IPR012975 NOPS
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR034526 PSF_NOPS
IPR034525 PSF_RRM1
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
PfamiView protein in Pfam
PF08075 NOPS, 1 hit
PF00076 RRM_1, 2 hits
SMARTiView protein in SMART
SM00360 RRM, 2 hits
SUPFAMiSSF54928 SSF54928, 1 hit
PROSITEiView protein in PROSITE
PS50102 RRM, 2 hits

Sequencei

Sequence statusi: Complete.

Q4KM71-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRDRFRSRG GGGGGFHRRG GGGGRGGLHD FRSPPPGMGL NQNRGPMGPG
60 70 80 90 100
PGGPKPPLPP PPPHQQQQQP PPQQPPPQQP PPHQQPPPHQ PPHQQPPPPP
110 120 130 140 150
QESKPVVPQG PGSAPGVSTA PPPAVSAPPA NPPTTGAPPG PGPTPTPPPA
160 170 180 190 200
VPSTAPGPPP PSTPSSGVST TPPQTGGPPP PPAGGAGPGP KQGPGPGGPK
210 220 230 240 250
GGKMPGGPKP GGGPGMGAPG GHPKPPHRGG GEPRGGRQHH APYHQQHHQG
260 270 280 290 300
PPPGGPGPRT EEKISDSEGF KANLSLLRRP GEKTYTQRCR LFVGNLPADI
310 320 330 340 350
TEDEFKRLFA KYGEPGEVFI NKGKGFGFIK LESRALAEIA KAELDDTPMR
360 370 380 390 400
GRQLRVRFAT HAAALSVRNL SPYVSNELLE EAFSQFGPIE RAVVIVDDRG
410 420 430 440 450
RSTGKGIVEF ASKPAARKAF ERCSEGVFLL TTTPRPVIVE PLEQLDDEDG
460 470 480 490 500
LPEKLAQKNP MYQKERETPP RFAQHGTFEY EYSQRWKSLD EMEKQQREQV
510 520 530 540 550
EKNMKDAKDK LESEMEDAYH EHQANLLRQD LMRRQEELRR MEELHSQEMQ
560 570 580 590 600
KRKEMQLRQE EERRRREEEM MIRQREMEEQ MRRQREESYS RMGYMDPRER
610 620 630 640 650
DMRMGGGGTM NMGDPYGSGG QKFPPLGGGG GIGYEANPGV PPATMSGSMM
660 670 680 690
GSDMRTERFG QGGAGPVGGQ GPRGMGPGTP AGYGRGREEY EGPNKKPRF
Length:699
Mass (Da):75,487
Last modified:August 2, 2005 - v1
Checksum:iE7BDCD191E4CE283
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC098731 mRNA Translation: AAH98731.1
RefSeqiNP_001020442.1, NM_001025271.1
UniGeneiRn.54645

Genome annotation databases

GeneIDi252855
KEGGirno:252855
UCSCiRGD:727923 rat

Similar proteinsi

Entry informationi

Entry nameiQ4KM71_RAT
AccessioniPrimary (citable) accession number: Q4KM71
Entry historyiIntegrated into UniProtKB/TrEMBL: August 2, 2005
Last sequence update: August 2, 2005
Last modified: March 28, 2018
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health