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Protein

Transmembrane protein 186

Gene

Tmem186

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Transmembrane protein 186
Gene namesi
Name:Tmem186
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 10

Organism-specific databases

RGDi1561167. Tmem186.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei69 – 91HelicalSequence analysisAdd BLAST23
Transmembranei104 – 124HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002794411 – 216Transmembrane protein 186Add BLAST216

Proteomic databases

PaxDbiQ4KLZ1.
PRIDEiQ4KLZ1.

PTM databases

iPTMnetiQ4KLZ1.
PhosphoSitePlusiQ4KLZ1.

Expressioni

Gene expression databases

BgeeiENSRNOG00000027087.
GenevisibleiQ4KLZ1. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000062154.

Family & Domainsi

Sequence similaritiesi

Belongs to the TMEM186 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IZSW. Eukaryota.
ENOG4111SG0. LUCA.
GeneTreeiENSGT00390000000087.
HOGENOMiHOG000059619.
HOVERGENiHBG107416.
InParanoidiQ4KLZ1.
OMAiYRFDAIR.
OrthoDBiEOG091G0YC4.
PhylomeDBiQ4KLZ1.
TreeFamiTF326623.

Family and domain databases

InterProiView protein in InterPro
IPR026571. Tmem186.
PANTHERiPTHR13603. PTHR13603. 1 hit.

Sequencei

Sequence statusi: Complete.

Q4KLZ1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFLLRAVPR LQGPAAWRRP LQQLWCRAGQ GDSIRWVGSR SPPSQEKPPG
60 70 80 90 100
TETEKFHTIY RFNAIRALGF LSRLKLAQTA VTVVALPPGF YCYSQGLMTL
110 120 130 140 150
SSLGLMSGIA SFALVMLCWM SHFFRRLVGI LYVNESGTLL RVAHLTFWGW
160 170 180 190 200
RQDTYCAVSD MIPLSESEER VQDVFVRIQQ YSGKQTFYLT LRYGRILDRD
210
RFSQVFGTLA TLKNSK
Length:216
Mass (Da):24,641
Last modified:August 2, 2005 - v1
Checksum:i114C413E8A3429DA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC098933 mRNA. Translation: AAH98933.1.
RefSeqiNP_001020927.1. NM_001025756.1.
UniGeneiRn.34474.

Genome annotation databases

EnsembliENSRNOT00000030290; ENSRNOP00000062154; ENSRNOG00000027087.
GeneIDi497863.
KEGGirno:497863.
UCSCiRGD:1561167. rat.

Similar proteinsi

Entry informationi

Entry nameiTM186_RAT
AccessioniPrimary (citable) accession number: Q4KLZ1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 6, 2007
Last sequence update: August 2, 2005
Last modified: May 10, 2017
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families