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Protein
Submitted name:

Vanin 1

Gene

Vnn1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei81Proton acceptorUniRule annotation1
Active sitei180Proton donorUniRule annotation1
Active sitei213NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-RNO-163125. Post-translational modification: synthesis of GPI-anchored proteins.
R-RNO-199220. Vitamin B5 (pantothenate) metabolism.
R-RNO-6798695. Neutrophil degranulation.

Names & Taxonomyi

Protein namesi
Submitted name:
Vanin 1Imported
Gene namesi
Name:Vnn1Imported
ORF Names:rCG_41942Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi1310075. Vnn1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_501142380924 – 512Sequence analysisAdd BLAST489

Expressioni

Gene expression databases

BgeeiENSRNOG00000016219.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000021694.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini41 – 308CN hydrolaseInterPro annotationAdd BLAST268

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG0806. Eukaryota.
COG0388. LUCA.
GeneTreeiENSGT00390000013823.
HOGENOMiHOG000007627.
HOVERGENiHBG003996.
KOiK08069.
OMAiVVNWTSY.
OrthoDBiEOG091G04QD.
TreeFamiTF323645.

Family and domain databases

CDDicd07567. biotinidase_like. 1 hit.
Gene3Di3.60.110.10. 1 hit.
InterProiView protein in InterPro
IPR012101. Biotinidase-like_euk.
IPR003010. C-N_Hydrolase.
IPR036526. C-N_Hydrolase_sf.
PfamiView protein in Pfam
PF00795. CN_hydrolase. 1 hit.
PIRSFiPIRSF011861. Biotinidase. 1 hit.
SUPFAMiSSF56317. SSF56317. 1 hit.
PROSITEiView protein in PROSITE
PS50263. CN_HYDROLASE. 1 hit.

Sequencei

Sequence statusi: Complete.

Q4KLZ0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLSRWLAWA AAFSVFCVLK VSSLDTFLAA VYEHAVILPK VTLLPVSHSE
60 70 80 90 100
ALALMNQNLD LLEGAILSAA KQGAHIIVTP EDGIYGVQFT RDTIYPYLED
110 120 130 140 150
IPDPQVNWIP CDNPERFGST PVQERLSCLA KNNSIYVVAN MGDKKPCNTS
160 170 180 190 200
DSHCPPDGRF QYNTDVVFDS RGKLVARYHK QNLFMGEEQF NAPPEPEVVT
210 220 230 240 250
FDTPFGKFGI FTCFDILFHD PAVTLVTEFQ VDTILFPTAW MDVLPHLAAI
260 270 280 290 300
EFHSAWAIGM GVNFLAANLH IPLRRMTGSG IYAPDSPRAF HYDRKTQEGK
310 320 330 340 350
LLLAQLDSHP SHSPVNWTSY ASSVEAPPTE KEEFRSFVFF DEFTFVELKG
360 370 380 390 400
ITGNYTVCQN DLCCHLSYQM SEKRADEVYA LGAFDGLHTV EGQYHLQICI
410 420 430 440 450
LLKCKTTNLR TCGSSVDTAS TRFEMFSLSG TFGTRYVFPE VLLSEVKLAP
460 470 480 490 500
GEFQVLSDGR LVSLKPTSGP VLTVGLFGRL YEKDWASNAS SDLIAHSLII
510
MLILAPIIHY LC
Length:512
Mass (Da):57,013
Last modified:August 2, 2005 - v1
Checksum:i3B812CED39D48812
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC128759 Genomic DNA. No translation available.
BC098934 mRNA. Translation: AAH98934.1.
CH474002 Genomic DNA. Translation: EDL87746.1.
RefSeqiNP_001020794.1. NM_001025623.1.
UniGeneiRn.16319.

Genome annotation databases

EnsembliENSRNOT00000021694; ENSRNOP00000021694; ENSRNOG00000016219.
GeneIDi29142.
KEGGirno:29142.

Similar proteinsi

Entry informationi

Entry nameiQ4KLZ0_RAT
AccessioniPrimary (citable) accession number: Q4KLZ0
Entry historyiIntegrated into UniProtKB/TrEMBL: August 2, 2005
Last sequence update: August 2, 2005
Last modified: December 20, 2017
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported