Unreviewed, UniProtKB/TrEMBL Q4KLL6 (Q4KLL6_RAT)

Names and origin

Protein names

Submitted name:
    Hras protein EMBL AAH99130.1

Gene names

Name:

Hras RGD 2827

Organism

Rattus norvegicus (Rat) EMBL AAH99130.1

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	251 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level.

Ontologies

Keywords
Ligand	GTP-binding RuleBase RU003312V0 Spearmint SPM003577 Nucleotide-binding
Gene Ontology (GO)
Biological process	Ras protein signal transduction Inferred from mutant phenotype. Source: RGD actin cytoskeleton organization Inferred from electronic annotation. Source: Compara apoptosis Inferred from mutant phenotype. Source: RGD cell aging Inferred from electronic annotation. Source: Compara endocytosis Inferred from electronic annotation. Source: Compara negative regulation of neuron apoptosis Inferred from electronic annotation. Source: Compara positive regulation of DNA replication Inferred from mutant phenotype. Source: RGD positive regulation of Rac protein signal transduction Inferred from electronic annotation. Source: Compara positive regulation of cell proliferation Inferred from electronic annotation. Source: Compara protein heterooligomerization Inferred from physical interaction. Source: RGD regulation of long-term neuronal synaptic plasticity Inferred from electronic annotation. Source: Compara regulation of synaptic transmission, GABAergic Inferred from electronic annotation. Source: Compara striated muscle cell differentiation Inferred from electronic annotation. Source: Compara visual learning Inferred from electronic annotation. Source: Compara
Cellular component	intracellular Inferred from electronic annotation. Source: InterPro membrane fraction Inferred from electronic annotation. Source: Compara plasma membrane Inferred from mutant phenotype. Source: RGD
Molecular function	GTP binding Inferred from electronic annotation. Source: UniProtKB-KW GTPase activity Inferred from electronic annotation. Source: InterPro protein C-terminus binding Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAH99130.1

Sequences

	Sequence		Length	Mass (Da)
	Q4KLL6-1 [UniParc]. Last modified August 2, 2005. Version 1. Checksum: 8D790D29A9709F82	FASTA	251	27,050
	10 20 30 40 50 60 AKSPPSAPGA RSPSRTRRGR SPCAGPVGAR PRPRPAPAPA PGAVAPASGG AGAPGLAAPV 70 80 90 100 110 120 EAMTEYKLVV VGAGGVGKSA LTIQLIQNHF VDEYDPTIED SYRKQVVIDG ETCLLDILDT 130 140 150 160 170 180 AGQEEYSAMR DQYMRTGEGF LCVFAINNTK SFEDIHQYRE QIKRVKDSDD VPMVLVGNKC 190 200 210 220 230 240 DLAARTVESR QAQDLARSYG IPYIETSAKT RQGVEDAFYT LVREIRQHKL RKLNPPDESG 250 PGCMSCKCVL S

References

[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Thymus EMBL AAH99130.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC099130 mRNA. Translation: AAH99130.1.
IPI	IPI00763926.
RefSeq	NP_001091711.1.
UniGene	Rn.102180 Rn.129785
3D structure databases
SMR	Q4KLL6. Positions 63-233.
ModBase	Search...
Protein-protein interaction databases
STRING	Q4KLL6.
Genome annotation databases
Ensembl	ENSRNOT00000022363; ENSRNOP00000022363; ENSRNOG00000016611; Rattus norvegicus. [Genome view]
GeneID	293621.
KEGG	rno:293621.
Organism-specific databases
CTD	293621.
Phylogenomic databases
HOVERGEN	Q4KLL6.
PhylomeDB	Q4KLL6.
Gene expression databases
Genevestigator	Q4KLL6.
Family and domain databases
InterPro	IPR003577. GTPase_Ras. IPR013753. Ras. IPR001806. Ras_GTPase. IPR015592. Ras_Ras_related. IPR020849. Ras_small_GTPase. IPR005225. Small_GTP_bd. [Graphical view]
PANTHER	PTHR11708:SF125. Ras_Ras_related. 1 hit.
Pfam	PF00071. Ras. 1 hit. [Graphical view]
PRINTS	PR00449. RASTRNSFRMNG.
SMART	SM00173. RAS. 1 hit. [Graphical view]
TIGRFAMs	TIGR00231. small_GTP. 1 hit.
PROSITE	PS51421. RAS. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q4KLL6_RAT

Accession

Primary (citable) accession number: Q4KLL6

Entry history

Integrated into UniProtKB/TrEMBL:	August 2, 2005
Last sequence update:	August 2, 2005
Last modified:	February 9, 2010
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)