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Q4KLK5

- Q4KLK5_RAT

UniProt

Q4KLK5 - Q4KLK5_RAT

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Protein
Submitted name:

Itgb2 protein

Gene

Itgb2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. protein complex binding Source: RGD
  2. protein heterodimerization activity Source: RGD
  3. receptor activity Source: InterPro

GO - Biological processi

  1. aging Source: RGD
  2. cell-matrix adhesion Source: InterPro
  3. cellular extravasation Source: RGD
  4. endothelial cell migration Source: RGD
  5. integrin-mediated signaling pathway Source: InterPro
  6. leukocyte cell-cell adhesion Source: RGD
  7. leukocyte migration involved in inflammatory response Source: RGD
  8. natural killer cell activation Source: RGD
  9. positive regulation of angiogenesis Source: RGD
  10. positive regulation of NF-kappaB transcription factor activity Source: RGD
  11. positive regulation of nitric oxide biosynthetic process Source: RGD
  12. single organismal cell-cell adhesion Source: RGD
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Itgb2 proteinImported
Gene namesi
Name:Itgb2Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi1305581. Itgb2.

Subcellular locationi

GO - Cellular componenti

  1. cell surface Source: RGD
  2. integrin complex Source: InterPro
  3. plasma membrane Source: RGD
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ4KLK5.

Structurei

3D structure databases

ProteinModelPortaliQ4KLK5.
SMRiQ4KLK5. Positions 19-122.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

PhylomeDBiQ4KLK5.

Family and domain databases

InterProiIPR015812. Integrin_bsu.
IPR015439. Integrin_bsu-2.
IPR014836. Integrin_bsu_cyt_dom.
IPR012896. Integrin_bsu_tail.
[Graphical view]
PANTHERiPTHR10082. PTHR10082. 1 hit.
PTHR10082:SF15. PTHR10082:SF15. 1 hit.
PfamiPF08725. Integrin_b_cyt. 1 hit.
PF07965. Integrin_B_tail. 1 hit.
[Graphical view]
PRINTSiPR01186. INTEGRINB.
SUPFAMiSSF69687. SSF69687. 1 hit.
PROSITEiPS00243. INTEGRIN_BETA. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4KLK5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGVPIPGADL SATLPHHTRC ESGYIGKNCE CQTQGRSSQE LEGNCRKDNS
60 70 80 90 100
SIVCSGLGDC ICGQCVCHTS DIPNKVIFGQ YCECDNFNCE RYDGQVCGGL
110 120 130 140 150
KRGSCSCGQC NCKEGFEGSA CQCQRSTTGC LNARLVECSG RGRCQCNRCI
160 170 180 190 200
CEKGYQPPLC EECPGCPLPC STYVFCAECL KFDKGPFQKN CSVQCANVTL
210 220 230 240 250
QTVPFKKKPC KERDSEGCWI TYTLQQKDGN AYNIHVDDDR ECVKGPNVAA
260 270 280 290 300
IIGGTVAGVV LIGVLLLVIW KALTHLTDLN EYRRFEKEKL KSQWNNDNPL
310
FKSATTTVMN PKFAES
Length:316
Mass (Da):34,629
Last modified:August 2, 2005 - v1
Checksum:i822785BF31B6F2A4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC099151 mRNA. Translation: AAH99151.1.
UniGeneiRn.42962.

Genome annotation databases

UCSCiRGD:1305581. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC099151 mRNA. Translation: AAH99151.1 .
UniGenei Rn.42962.

3D structure databases

ProteinModelPortali Q4KLK5.
SMRi Q4KLK5. Positions 19-122.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

UCSCi RGD:1305581. rat.

Organism-specific databases

RGDi 1305581. Itgb2.

Phylogenomic databases

PhylomeDBi Q4KLK5.

Gene expression databases

Genevestigatori Q4KLK5.

Family and domain databases

InterProi IPR015812. Integrin_bsu.
IPR015439. Integrin_bsu-2.
IPR014836. Integrin_bsu_cyt_dom.
IPR012896. Integrin_bsu_tail.
[Graphical view ]
PANTHERi PTHR10082. PTHR10082. 1 hit.
PTHR10082:SF15. PTHR10082:SF15. 1 hit.
Pfami PF08725. Integrin_b_cyt. 1 hit.
PF07965. Integrin_B_tail. 1 hit.
[Graphical view ]
PRINTSi PR01186. INTEGRINB.
SUPFAMi SSF69687. SSF69687. 1 hit.
PROSITEi PS00243. INTEGRIN_BETA. 3 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: SpleenImported.

Entry informationi

Entry nameiQ4KLK5_RAT
AccessioniPrimary (citable) accession number: Q4KLK5
Entry historyi
Integrated into UniProtKB/TrEMBL: August 2, 2005
Last sequence update: August 2, 2005
Last modified: October 29, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)