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Q4KLK5 (Q4KLK5_RAT) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length316 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

Ontologies

Gene Ontology (GO)
   Biological_processaging

Inferred from expression pattern PubMed 22206492. Source: RGD

cell-matrix adhesion

Inferred from electronic annotation. Source: InterPro

cellular extravasation

Inferred from mutant phenotype PubMed 10363598. Source: RGD

endothelial cell migration

Inferred from mutant phenotype PubMed 16825578. Source: RGD

integrin-mediated signaling pathway

Inferred from electronic annotation. Source: InterPro

leukocyte cell-cell adhesion

Inferred from mutant phenotype PubMed 11804664. Source: RGD

leukocyte migration involved in inflammatory response

Inferred from mutant phenotype PubMed 10363598. Source: RGD

natural killer cell activation

Inferred from mutant phenotype PubMed 9413744. Source: RGD

positive regulation of NF-kappaB transcription factor activity

Inferred from mutant phenotype PubMed 9062344. Source: RGD

positive regulation of angiogenesis

Inferred from mutant phenotype PubMed 16825578. Source: RGD

positive regulation of nitric oxide biosynthetic process

Inferred from mutant phenotype PubMed 9062344. Source: RGD

single organismal cell-cell adhesion

Inferred from mutant phenotype PubMed 16825578PubMed 8938183. Source: RGD

   Cellular_componentcell surface

Inferred from direct assay PubMed 16825578PubMed 8938183. Source: RGD

integrin complex

Inferred from electronic annotation. Source: InterPro

plasma membrane

Inferred from direct assay PubMed 14595007. Source: RGD

   Molecular_functionprotein complex binding

Inferred from physical interaction PubMed 10556544. Source: RGD

protein heterodimerization activity

Inferred from physical interaction PubMed 1672643. Source: RGD

receptor activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q4KLK5 [UniParc].

Last modified August 2, 2005. Version 1.
Checksum: 822785BF31B6F2A4

FASTA31634,629
        10         20         30         40         50         60 
MGVPIPGADL SATLPHHTRC ESGYIGKNCE CQTQGRSSQE LEGNCRKDNS SIVCSGLGDC 

        70         80         90        100        110        120 
ICGQCVCHTS DIPNKVIFGQ YCECDNFNCE RYDGQVCGGL KRGSCSCGQC NCKEGFEGSA 

       130        140        150        160        170        180 
CQCQRSTTGC LNARLVECSG RGRCQCNRCI CEKGYQPPLC EECPGCPLPC STYVFCAECL 

       190        200        210        220        230        240 
KFDKGPFQKN CSVQCANVTL QTVPFKKKPC KERDSEGCWI TYTLQQKDGN AYNIHVDDDR 

       250        260        270        280        290        300 
ECVKGPNVAA IIGGTVAGVV LIGVLLLVIW KALTHLTDLN EYRRFEKEKL KSQWNNDNPL 

       310 
FKSATTTVMN PKFAES 

« Hide

References

[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. expand/collapse author list , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Spleen EMBL AAH99151.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC099151 mRNA. Translation: AAH99151.1.
UniGeneRn.42962.

3D structure databases

ProteinModelPortalQ4KLK5.
SMRQ4KLK5. Positions 19-122.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

UCSCRGD:1305581. rat.

Organism-specific databases

RGD1305581. Itgb2.

Phylogenomic databases

InParanoidQ4KLK5.
PhylomeDBQ4KLK5.

Gene expression databases

GenevestigatorQ4KLK5.

Family and domain databases

InterProIPR015812. Integrin_bsu.
IPR015439. Integrin_bsu-2.
IPR014836. Integrin_bsu_cyt_dom.
IPR012896. Integrin_bsu_tail.
[Graphical view]
PANTHERPTHR10082. PTHR10082. 1 hit.
PTHR10082:SF15. PTHR10082:SF15. 1 hit.
PfamPF08725. Integrin_b_cyt. 1 hit.
PF07965. Integrin_B_tail. 1 hit.
[Graphical view]
PRINTSPR01186. INTEGRINB.
SUPFAMSSF69687. SSF69687. 1 hit.
PROSITEPS00243. INTEGRIN_BETA. 3 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ4KLK5_RAT
AccessionPrimary (citable) accession number: Q4KLK5
Entry history
Integrated into UniProtKB/TrEMBL: August 2, 2005
Last sequence update: August 2, 2005
Last modified: July 9, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)