Q4KLJ8 (PDCL3_RAT) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosducin-like protein 3

Gene names

Name:

Pdcl3

Organism

Rattus norvegicus (Rat) [Reference proteome]

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	240 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Modulates the activation of caspases during apoptosis By similarity.
Subcellular location	Cytoplasm By similarity.
Post-translational modification	Phosphorylated By similarity.
Sequence similarities	Belongs to the phosducin family.

Ontologies

Keywords
Biological process	Apoptosis Host-virus interaction
Cellular component	Cytoplasm
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	apoptotic process Inferred from electronic annotation. Source: UniProtKB-KW virus-host interaction Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 240	240	Phosducin-like protein 3		PRO_0000246160
Amino acid modifications
	Modified residue	235	1	Phosphoserine By similarity
	Modified residue	237	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q4KLJ8 [UniParc]. Last modified August 2, 2005. Version 1. Checksum: 950F1D9C0A4498E8	FASTA	240	27,699
	10 20 30 40 50 60 MQDPNADTEW NDILRKKGIL PPKESLKELE EEEEGKEEQR LQQSVVKTYE DMTLEELQEN 70 80 90 100 110 120 EDEFSEEDER AIEMYRQQRL AEWKATQLRN KFGEVLEISG KDYVQEVTKA GEGLWVVLHL 130 140 150 160 170 180 YKQGIPLCSL INHHLSGLAR KFPDVKFIKA ISTTCIPNYP DRNLPTVFVY REGDIKAQFI 190 200 210 220 230 240 GPLVFGGMNL TIDELEWKLS ESGAIKTELE ENPKKAIKDV LLSSVRDPVP MRRDSDSEDD

References

[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Thymus.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC099162 mRNA. Translation: AAH99162.1.
IPI	IPI00362201.
RefSeq	NP_001020880.1. NM_001025709.1.
UniGene	Rn.103207.
3D structure databases
ProteinModelPortal	Q4KLJ8.
ModBase	Search...
Protein-protein interaction databases
STRING	10116.ENSRNOP00000017882.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSRNOT00000017882; ENSRNOP00000017882; ENSRNOG00000013286.
GeneID	316348.
KEGG	rno:316348.
Organism-specific databases
CTD	79031.
RGD	1309663. Pdcl3.
Phylogenomic databases
eggNOG	NOG294106.
GeneTree	ENSGT00530000062970.
HOGENOM	HOG000184445.
HOVERGEN	HBG108238.
InParanoid	Q4KLJ8.
OrthoDB	EOG4ZCT5P.
Gene expression databases
Genevestigator	Q4KLJ8.
GermOnline	ENSRNOG00000013286. Rattus norvegicus.
Family and domain databases
Gene3D	3.40.30.10. 1 hit.
InterPro	IPR006442. Antitoxin_Phd/YefM. IPR024253. Phosducin_thioredoxin-like_dom. IPR012336. Thioredoxin-like_fold. [Graphical view]
Pfam	PF02114. Phosducin. 1 hit. [Graphical view]
SUPFAM	SSF52833. Thiordxn-like_fd. 1 hit.
TIGRFAMs	TIGR01552. phd_fam. 1 hit.
ProtoNet	Search...
Other
NextBio	670753.

Entry information

Entry name

PDCL3_RAT

Accession

Primary (citable) accession number: Q4KLJ8

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 25, 2006
Last sequence update:	August 2, 2005
Last modified:	April 3, 2013
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program