ID   DUPD1_XENLA             Reviewed;         209 AA.
AC   Q4KL92;
DT   24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   24-JUL-2007, sequence version 2.
DT   16-JUN-2009, entry version 22.
DE   RecName: Full=Dual specificity phosphatase DUPD1;
DE            EC=3.1.3.48;
DE            EC=3.1.3.16;
GN   Name=dupd1;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;
OC   Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: Protein tyrosine phosphate + H(2)O = protein
CC       tyrosine + phosphate.
CC   -!- CATALYTIC ACTIVITY: A phosphoprotein + H(2)O = a protein +
CC       phosphate.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the protein-tyrosine phosphatase family.
CC       Non-receptor class dual specificity subfamily.
CC   -!- SIMILARITY: Contains 1 tyrosine-protein phosphatase domain.
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DR   EMBL; BC099351; AAH99351.1; ALT_INIT; mRNA.
DR   EMBL; BC133235; AAI33236.1; ALT_INIT; mRNA.
DR   UniGene; Xl.51670; -.
DR   HSSP; P51452; 1VHR.
DR   Xenbase; XB-FEAT-5944518; dupd1.
DR   HOVERGEN; Q4KL92; -.
DR   BRENDA; 3.1.3.16; 648.
DR   BRENDA; 3.1.3.48; 648.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphata...; IEA:InterPro.
DR   GO; GO:0006470; P:protein amino acid dephosphorylation; IEA:InterPro.
DR   InterPro; IPR000387; Tyr_Pase.
DR   InterPro; IPR016130; Tyr_Pase_AS.
DR   InterPro; IPR000340; Tyr_Pase_dual_specific.
DR   Pfam; PF00782; DSPc; 1.
DR   SMART; SM00195; DSPc; 1.
DR   PROSITE; PS00383; TYR_PHOSPHATASE_1; FALSE_NEG.
DR   PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR   PROSITE; PS50054; TYR_PHOSPHATASE_DUAL; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Hydrolase; Protein phosphatase.
FT   CHAIN         1    209       Dual specificity phosphatase DUPD1.
FT                                /FTId=PRO_0000295891.
FT   DOMAIN       45    192       Tyrosine-protein phosphatase.
FT   ACT_SITE    138    138       Phosphocysteine intermediate (By
FT                                similarity).
SQ   SEQUENCE   209 AA;  23750 MW;  6BB945FAF4E4A539 CRC64;
     MPADTPIRKK PNAYASVVDP DTGYCTPGAF ELERLFWHGA PKYTHVNEVW PNLYIGDEKT
     ALDRYSLEKN GFTHILNAAH GRWNVDTGPE YYSDMTVEYY GVEAEDLPSF NLSQFFYPAA
     QFIHKALSTP NSKLLVNCAM GRSRSASLVL AYLMIYKNMT VVESITQVLK HRCILPNRGF
     LKQLRELDIK LALEKRDTHG TANKAQKDD
//