Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q4KKR7 (SYGA_PSEF5) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glycine--tRNA ligase alpha subunit

EC=6.1.1.14
Alternative name(s):
Glycyl-tRNA synthetase alpha subunit
Short name=GlyRS
Gene names
Name:glyQ
Ordered Locus Names:PFL_0014
OrganismPseudomonas fluorescens (strain Pf-5 / ATCC BAA-477) [Complete proteome] [HAMAP]
Taxonomic identifier220664 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length317 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP-Rule MF_00254

Subunit structure

Tetramer of two alpha and two beta subunits By similarity.

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00254.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycyl-tRNA aminoacylation

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

glycine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 317317Glycine--tRNA ligase alpha subunit HAMAP-Rule MF_00254
PRO_1000047470

Sequences

Sequence LengthMass (Da)Tools
Q4KKR7 [UniParc].

Last modified August 2, 2005. Version 1.
Checksum: 0BB3AFD6CCB2A600

FASTA31736,247
        10         20         30         40         50         60 
MSQPTPAVRT FQDLILALQQ YWAEQGCVVL QPYDMEVGAG TFHTATFLRA IGPETWNAAY 

        70         80         90        100        110        120 
VQPSRRPTDG RYGENPNRLQ HYYQFQVVLK PNPENFQELY LGSLKHVGLD PLVHDIRFVE 

       130        140        150        160        170        180 
DNWESPTLGA WGLGWEVWLN GMEVTQFTYF QQAGGIECYP VTGEITYGLE RLAMYLQGVD 

       190        200        210        220        230        240 
SVYDLVWADG PFGKVTYGDV FHQNEVEQST YNFEHANVEK LFELFDFYES EAKRLIELDQ 

       250        260        270        280        290        300 
PLPLPSYEMV LKASHTFNLL DARRAISVTA RQQYILRVRT LARSVAQAYL LARAKLGFPM 

       310 
ATPDLRDEVL AKLEAAQ 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000076 Genomic DNA. Translation: AAY95432.1.
RefSeqYP_257166.1. NC_004129.6.

3D structure databases

ProteinModelPortalQ4KKR7.
SMRQ4KKR7. Positions 11-294.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING220664.PFL_0014.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAY95432; AAY95432; PFL_0014.
GeneID3480614.
KEGGpfl:PFL_0014.
PATRIC19869133. VBIPseFlu72549_0014.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0752.
HOGENOMHOG000264291.
KOK01878.
OMADEYHASS.
OrthoDBEOG661H9S.

Enzyme and pathway databases

BioCycPFLU220664:GIX8-14-MONOMER.

Family and domain databases

HAMAPMF_00254. Gly_tRNA_synth_alpha.
InterProIPR006194. Gly-tRNA-synth_heterodimer.
IPR002310. Gly-tRNA_ligase_asu.
[Graphical view]
PfamPF02091. tRNA-synt_2e. 1 hit.
[Graphical view]
PRINTSPR01044. TRNASYNTHGA.
TIGRFAMsTIGR00388. glyQ. 1 hit.
PROSITEPS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYGA_PSEF5
AccessionPrimary (citable) accession number: Q4KKR7
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 2, 2005
Last modified: May 14, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries